118. 脊髄髄膜瘤 Myelomeningocele Clinical trials / Disease details


臨床試験数 : 10 薬物数 : 18 - (DrugBank : 7) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 12

  
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PhaseCountries
1NCT04652908
(ClinicalTrials.gov)
June 21, 202125/11/2020Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe TrialPhase 1/2a Trial of Placental Mesenchymal Stem Cells for Repair of Fetal MyelomeningoceleMyelomeningoceleBiological: Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix;Other: Untreated contemporaneous cohortDiana Lee FarmerCalifornia Institute for Regenerative Medicine (CIRM)Recruiting19 Weeks25 WeeksAll55Phase 1/Phase 2United States
2NCT04738539
(ClinicalTrials.gov)
March 2, 20211/2/2021Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic StudiesEfficacy of Contrast Enhanced Voiding Urosonography for Urodynamic StudiesMyelomeningocele;Neurogenic Bladder;Tethered Cord Syndrome;Bladder, Neurogenic;Urologic Diseases;Neurologic DysfunctionDrug: Contrast Enhanced Voiding Urosonography with Urodynamic Testing;Diagnostic Test: Urodynamic TestingUniversity of VirginiaNULLRecruitingN/A18 YearsAll105United States
3JPRN-UMIN000040088
2019/07/0107/04/2020Safety Assessment Clinical Test of Fetal Surgery for MyelomeningoceleSafety Assessment Clinical Test of Fetal Surgery for Myelomeningocele - Safety Assessment Clinical Test of Fetal Surgery for Myelomeningocele MyelomeningoceleMMC(Myelomeningocele) open fetal surgeryOSAKA UniversityDepartment of MedicineDivision of Obstetrics and GynecologyNULLRecruiting20years-oldNot applicableFemale15Not selectedJapan
4NCT04027374
(ClinicalTrials.gov)
July 1, 201916/7/2019Stress-associated Epigenetic Alterations in Newborns After Fetal SurgeryEpigenetic Alterations in Stress Regulation Genes Among Newborns After Fetal Surgery for Myelomeningocele Repair: An Exploratory StudyMeningomyeloceleProcedure: Fetal surgery for MMC repairUniversity Children's Hospital, ZurichUniversity of Zurich;Psychiatric University Hospital, ZurichRecruitingN/A3 MonthsAll90Switzerland
5NCT03936322
(ClinicalTrials.gov)
May 7, 20191/5/2019Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot StudyMinimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot StudySpina Bifida;Myelomeningocele;Neural Tube DefectsDevice: Minimally invasive fetoscopic repair of MMCMayo ClinicNULLActive, not recruiting18 YearsN/AFemale3N/AUnited States
6NCT04362592
(ClinicalTrials.gov)
November 2, 201824/3/2020In-Utero Endoscopic Correction of Spina BifidaIn-Utero Endoscopic Correction of Spina Bifida: Laparotomy or PercutaneousNeural Tube Defects;Spina Bifida;MyelomeningoceleDevice: In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique;Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization TechniqueUniversity of Southern CaliforniaNULLRecruiting18 Years52 YearsFemale33N/AUnited States
7NCT02390895
(ClinicalTrials.gov)
May 17, 201715/2/2015Prenatal Endoscopic Repair of Fetal Spina BifidaPrenatal Endoscopic Repair of Fetal Spina BifidaMyelomeningoceleProcedure: endoscopic repair of myelomeningocele before 26 SAAssistance Publique - Hôpitaux de ParisNULLActive, not recruiting18 YearsN/AFemale7N/AFrance
8NCT04468568
(ClinicalTrials.gov)
January 8, 20171/3/2020In Utero Repair of Myelomeningocele: Atosiban Versus TerbutalineAssessment of Maternal Blood Gas Changes When Using Atosiban and Terbutaline as Tocolytic Agents, During in Utero Repair of MyelomeningoceleMyelomeningocele;Terbutaline Adverse Reaction;Pregnancy; Malformation Central Nervous SystemDrug: Atosiban;Drug: TerbutalineUniversity of Sao Paulo General HospitalNULLRecruiting18 Years40 YearsFemale28N/ABrazil
9NCT04186338
(ClinicalTrials.gov)
December 1, 20162/12/2019Daily Physical Activity in MyelomeningoceleDaily Physical Activity in Children and Adolescents With Low Lumbar and Sacral Level MyelomeningocelePhysical ActivityDevice: Omnidirectional accelerometer monitor (3x3 cm and 16 g, Actical®, Philips Respironics)Marmara UniversityNULLCompleted6 Years16 YearsAll20NULL
10NCT00175123
(ClinicalTrials.gov)
May 20059/9/2005Effect of Botulinum Toxin in Neurogenic Bladders in Children With MyelomeningocelePhase 4 Study of the Effect of Botulinum-A Toxin Injected in Neurogenic Overactive Bladders of Children Born With MyelomeningoceleMyelomeningocele;Bladder, NeurogenicDrug: Botulinum A toxinUniversity of AarhusAarhus University HospitalActive, not recruiting2 Years16 YearsBoth30Phase 4Denmark