Disease details

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

3 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01973491 (ClinicalTrials.gov)	February 28, 2014	23/10/2013	ATX-MS-1467 in Multiple Sclerosis	An Open-label, One-arm, Proof of Concept Trial to Evaluate the Safety of ATX-MS-1467 (MSC2358825A) and Its Effect on Immune Tolerance in Subjects With Relapsing Multiple Sclerosis	Multiple Sclerosis	Drug: ATX-MS-1467	Merck KGaA	NULL	Completed	18 Years	65 Years	All	37	Phase 2	Germany
2	EUCTR2013-002916-28-LV (EUCTR)	12/12/2013	16/10/2013	An Open-label, One-arm, Proof of Concept Trial to Evaluate the Safety of ATX-MS-1467 (MSC2358825A) and its Effect on Immune Tolerance in Subjects with Relapsing Multiple Sclerosis	An Open-label, One-arm, Proof of Concept Trial to Evaluate the Safety of ATX-MS-1467 (MSC2358825A) and its Effect on Immune Tolerance in Subjects with Relapsing Multiple Sclerosis	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10067063;Term: Progressive relapsing multiple sclerosis;System Organ Class: 10029205 - Nervous system disorders ;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Product Name: ATX-MS-1467 Product Code: MSC2358825A INN or Proposed INN: MSC2304479A INN or Proposed INN: MSC2304480A INN or Proposed INN: MSC2304481A INN or Proposed INN: MSC2304482A	Merck KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): no	Russian Federation;Latvia
3	NCT01097668 (ClinicalTrials.gov)	March 2010	31/3/2010	ATX-MS-1467 in Patients With Relapsing Forms of Multiple Sclerosis	SAFETY AND PROOF OF PRINCIPLE STUDY OF ATX-MS-1467 IN PATIENTS WITH RELAPSING MULTIPLE SCLEROSIS: OPEN LABEL UPWARD TITRATION OVER FIVE DOSE LEVELS AND USING TWO ROUTES OF ADMINISTRATION (INTRADERMAL AND SUBCUTANEOUS).	Relapsing Remitting Multiple Sclerosis	Biological: ATX-MS-1467	Apitope Technology (Bristol) Ltd.	Aptiv Solutions;ClinStar, LLC	Completed	18 Years	55 Years	All	43	Phase 1	Russian Federation;United Kingdom