13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

241 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-004128-41-BG (EUCTR)	15/02/2022	15/10/2021	A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimodin Children and ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE SAFETY AND EFFICAC ...	Relapsing-Remitting Multiple Sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063399;T ...	Trade Name: Ocrevus INN or Proposed INN: Ocrelizumab Other descriptive name: OCRELIZUMAB Trade Name: Gi ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	233	Phase 3	United States;Serbia;Portugal;Greece;Spain;Ukraine;Russian Federation;Italy;Switzerland;France;Denma ...
2	NCT05123703 (ClinicalTrials.gov)	February 4, 2022	16/11/2021	A Study To Evaluate Safety And Efficacy Of Ocrelizumab In Comparison With FingolimodIn Children And ...	A Phase III Multicenter, Randomized, Double-Blind, Double-Dummy Study To Evaluate Safety And Efficac ...	Relapsing-Remitting Multiple Sclerosis	Drug: Ocrelizumab;Other: Ocrelizumab Placebo;Drug: Fingolimod;Other: Fingolimod Placebo	Hoffmann-La Roche	PPD	Recruiting	10 Years	17 Years	All	233	Phase 3	United States;Argentina;Spain;Ukraine;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Denmark;Germa ...
3	EUCTR2020-004128-41-NL (EUCTR)	22/12/2021	14/09/2021	A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimodin Children and ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE SAFETY AND EFFICAC ...	Relapsing-Remitting Multiple Sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063399;T ...	Trade Name: Ocrevus INN or Proposed INN: Ocrelizumab Other descriptive name: OCRELIZUMAB Trade Name: Gi ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	233	Phase 3	United States;Serbia;Portugal;Greece;Spain;Ukraine;Russian Federation;Italy;Switzerland;France;Austr ...
4	EUCTR2020-004128-41-BE (EUCTR)	10/12/2021	10/12/2021	A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimodin Children and ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE SAFETY AND EFFICAC ...	Relapsing-Remitting Multiple Sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063399;T ...	Trade Name: Ocrevus INN or Proposed INN: Ocrelizumab Other descriptive name: OCRELIZUMAB Trade Name: Gi ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	233	Phase 3	United States;Serbia;Portugal;Greece;Spain;Ukraine;Russian Federation;Italy;Switzerland;France;Denma ...
5	EUCTR2020-002700-39-HR (EUCTR)	29/11/2021	06/12/2021	Efficacy and safety of ofatumumab and siponimod compared to fingolimodin pediatric patients with mul ...	A 2-year randomized, 3-arm, double-blind, non-inferiority study comparing the efficacy and safety of ...	Multiple Sclerosis in pediatric patients MedDRA version: 20.1;Level: PT;Classification code 10028245 ...	Trade Name: Kesimpta Product Name: ofatumumab Product Code: OMB157 INN or Proposed INN: OFATUMUMAB Trade ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	180	Phase 3	United States;Serbia;Portugal;Taiwan;Estonia;Slovakia;Spain;Ukraine;Chile;Israel;Russian Federation; ...
6	EUCTR2020-004128-41-GR (EUCTR)	23/11/2021	06/10/2021	A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimodin Children and ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE SAFETY AND EFFICAC ...	Relapsing-Remitting Multiple Sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063399;T ...	Trade Name: Ocrevus INN or Proposed INN: Ocrelizumab Other descriptive name: OCRELIZUMAB Trade Name: Gi ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	233	Phase 3	United States;Serbia;Portugal;Greece;Spain;Ukraine;Russian Federation;Switzerland;Italy;France;Austr ...
7	EUCTR2020-004128-41-IT (EUCTR)	11/10/2021	07/10/2021	A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimodin Children and ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE SAFETY AND EFFICAC ...	Relapsing-Remitting Multiple Sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063399;T ...	Trade Name: GILENYA - 0.5 MG - CAPSULE RIGIDE - USO ORALE Product Name: N/A Product Code: [N/A] INN or ...	F. HOFFMANN - LA ROCHE LTD.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	233	Phase 3	United States;Serbia;Portugal;Greece;Spain;Ukraine;Russian Federation;Italy;Switzerland;France;Austr ...
8	NCT04926818 (ClinicalTrials.gov)	October 5, 2021	14/6/2021	Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimodin Pediatric Patients With Mul ...	A 2-year Randomized, 3-arm, Double-blind, Non-inferiority Study Comparing the Efficacy and Safety of ...	Multiple Sclerosis (MS)	Drug: Fingolimod;Drug: Ofatumumab;Drug: Siponimod;Other: Fingolimodplacebo;Other: Siponimodplacebo;O ...	Novartis Pharmaceuticals	NULL	Recruiting	10 Years	17 Years	All	180	Phase 3	United States;Australia;Austria;Belgium;France;Germany;India;Latvia;Mexico;Poland;Portugal;Russian F ...
9	EUCTR2020-004128-41-PL (EUCTR)	04/10/2021	13/09/2021	A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimodin Children and ...	A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE SAFETY AND EFFICAC ...	Relapsing-Remitting Multiple Sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063399;T ...	Trade Name: Ocrevus INN or Proposed INN: Ocrelizumab Other descriptive name: OCRELIZUMAB Trade Name: Gi ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	233	Phase 3	United States;Serbia;Portugal;Greece;Spain;Ukraine;Russian Federation;Italy;Switzerland;France;Austr ...
10	EUCTR2020-002700-39-SK (EUCTR)	04/10/2021	16/06/2021	Efficacy and safety of ofatumumab and siponimod compared to fingolimodin pediatric patients with mul ...	A 2-year randomized, 3-arm, double-blind, non-inferiority study comparing the efficacy and safety of ...	Multiple Sclerosis in pediatric patients MedDRA version: 20.1;Level: PT;Classification code 10028245 ...	Trade Name: Kesimpta Product Name: ofatumumab Product Code: OMB157 INN or Proposed INN: OFATUMUMAB Trade ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	180	Phase 3	United States;Portugal;Serbia;Taiwan;Estonia;Slovakia;Spain;Ukraine;Chile;Israel;Russian Federation; ...

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