13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

37 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2012-005450-30-AT (EUCTR)	08/01/2014	11/11/2013	Investigation of neutralising antibodies against interferon-beta in patients with multiple sclerosis ...	Anti-Biopharmaceutical Immunization: Prediction and analysis of clinical relevance to minimize the r ...	Development of neutralising antibodies against Interferon-beta in the treatment of multiple sclerosi ...	Trade Name: Avonex INN or Proposed INN: Interferon-beta 1a Other descriptive name: INTERFERON BETA -1A Tr ...	Medizinische Universität Innsbruck	NULL	Not Recruiting			Female: yes Male: yes	100	Phase 4	Austria;Sweden
2	EUCTR2009-017003-28-IT (EUCTR)	12/04/2010	08/04/2010	Relationship between IL-6 and TNF-α polymorphism and flu-like syndrome development in multiple scler ...	Relationship between IL-6 and TNF-α polymorphism and flu-like syndrome development in multiple scler ...	multiple sclerosis MedDRA version: 9.1;Level: SOC;Classification code 10029205 MedDRA version: 9.1;L ...	Trade Name: AVONEX INN or Proposed INN: Interferon beta -1a	BIOGEN-DOMPE` SRL	NULL	Not Recruiting			Female: yes Male: yes			Italy
3	EUCTR2008-004954-34-AT (EUCTR)	21/01/2010	09/12/2008	Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX)	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono S.A. - Geneva, an affiliate of Merck KGaA, Darmstadt, Germany	NULL	Not Recruiting			Female: yes Male: yes	492		Portugal;Serbia;Estonia;Morocco;Slovakia;Greece;Spain;Lebanon;Israel;Russian Federation;Italy;France ...
4	EUCTR2008-004954-34-PL (EUCTR)	09/09/2009	05/06/2009	Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX)	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono S.A. - Geneva, an affiliate of Merck KGaA, Darmstadt, Germany	NULL	Not Recruiting			Female: yes Male: yes	492		Serbia;Portugal;Estonia;Slovakia;Morocco;Greece;Spain;Lebanon;Russian Federation;Israel;Italy;France ...
5	EUCTR2008-004954-34-BG (EUCTR)	28/05/2009	29/05/2009	Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX)	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono S.A. - Geneva, an affiliate of Merck KGaA, Darmstadt, Germany	NULL	Not Recruiting			Female: yes Male: yes	492		Portugal;Serbia;Estonia;Morocco;Slovakia;Greece;Spain;Lebanon;Israel;Russian Federation;Italy;France ...
6	EUCTR2008-004954-34-GR (EUCTR)	19/05/2009	06/03/2009	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono International, a branch of Laboratoires Serono SA an affiliate of Merck KGaA, Darmstadt ...	NULL	Not Recruiting			Female: yes Male: yes	492		Portugal;Estonia;Greece;Finland;Spain;Austria;Italy;France;Czech Republic;Poland;Belgium;Bulgaria;Ge ...
7	EUCTR2008-004954-34-DE (EUCTR)	05/05/2009	15/01/2009	Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX)	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono S.A. - Geneva, an affiliate of Merck KGaA, Darmstadt, Germany	NULL	Not Recruiting			Female: yes Male: yes	492		Serbia;Portugal;Estonia;Slovakia;Morocco;Greece;Spain;Lebanon;Russian Federation;Israel;Italy;France ...
8	EUCTR2008-004954-34-FR (EUCTR)	08/04/2009	17/03/2009	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono S.A.- Geneva, an affiliate of Merck KGaA, Darmstadt, Germany	NULL	Not Recruiting			Female: yes Male: yes	492	Phase 3	Portugal;Estonia;Slovakia;Greece;Finland;Spain;Austria;Italy;France;Czech Republic;Poland;Belgium;Bu ...
9	EUCTR2007-004452-36-GB (EUCTR)	24/03/2009	01/02/2008	A multi-center double-blind parallel-group placebo-controlled study of the efficacy and safety of te ...	A multi-center double-blind parallel-group placebo-controlled study of the efficacy and safety of te ...	Multiple sclerosis MedDRA version: 15.0;Level: PT;Classification code 10028245;Term: Multiple sclero ...	Product Name: Teriflunomide Product Code: HMR 1726D INN or Proposed INN: Teriflunomide Product Name: Te ...	Sanofi-aventis recherche & développement	NULL	Not Recruiting			Female: yes Male: yes	1110	Phase 3	Belarus;United States;Philippines;Estonia;Slovakia;Greece;Spain;Thailand;Ukraine;Chile;France;Austra ...
10	EUCTR2008-004954-34-LV (EUCTR)	12/03/2009	27/02/2009	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Double-blind extension of the study 27025 (REFLEX) to obtain long-term follow-up data in patients wi ...	Subjects of high risk of converting to Multiple Sclerosis or subjects already converted to Multiple ...	Trade Name: Rebif INN or Proposed INN: Interferon-beta 1a	Merck Serono S.A. - Geneva, an affiliate of Merck KGaA, Darmstadt, Germany	NULL	Not Recruiting			Female: yes Male: yes	492		Portugal;Estonia;Greece;Finland;Spain;Austria;Italy;France;Czech Republic;Poland;Belgium;Bulgaria;La ...

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