13. 多発性硬化症／視神経脊髄炎 Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

8 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03161028 (ClinicalTrials.gov)	July 1, 2018	18/5/2017	Lipoic Acid for Progressive Multiple Sclerosis (MS)	Lipoic Acid for the Treatment of Progressive Multiple Sclerosis	Multiple Sclerosis	Drug: Lipoic acid;Drug: Placebo	VA Office of Research and Development	NULL	Recruiting	18 Years	70 Years	All	118	Phase 2	United States;Canada
2	NCT03493841 (ClinicalTrials.gov)	June 8, 2018	21/3/2018	Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis	Comparing Gastrointestinal Tolerability and Absorption of Racemic Lipoic Acidand R-lipoic Acidin Pro ...	Multiple Sclerosis;Progressive Multiple Sclerosis;Secondary Progressive Multiple Sclerosis;Primary P ...	Drug: Alpha Lipoic Acid	Rebecca Spain	NULL	Completed	18 Years	N/A	All	20	Phase 1	United States
3	NCT02133664 (ClinicalTrials.gov)	June 2014	6/5/2014	Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis	Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis	Multiple Sclerosis;Cognition	Drug: lipoic acid and omega-3 fatty acids;Drug: Placebo	Oregon Health and Science University	National Multiple Sclerosis Society	Completed	18 Years	65 Years	All	54	Phase 1/Phase 2	United States
4	NCT01381354 (ClinicalTrials.gov)	October 2010	26/5/2011	Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis ...	Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis ...	Multiple Sclerosis	Other: Progressive exercise;Device: Neuromuscular electrical stimulation delivered using the electri ...	University of Iowa	Direct MS Canada;DJO Incorporated;Pinnaclife Inc.;TZ Press, LLC	Completed	18 Years	65 Years	All	38	Phase 1	United States
5	NCT01188811 (ClinicalTrials.gov)	October 2010	25/8/2010	Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)	Lipoic Acid for Neuroprotection in Secondary Progressive MS	Multiple Sclerosis, Chronic Progressive	Drug: lipoic acid;Drug: Placebo	VA Office of Research and Development	Oregon Health and Science University	Completed	40 Years	70 Years	All	54	Phase 2/Phase 3	United States
6	NCT00997438 (ClinicalTrials.gov)	August 2010	16/10/2009	Defining the Anti-inflammatory Role of Lipoic Acid in Multiple Sclerosis	Defining the Anti-inflammatory Role of Lipoic Acid in Multiple Sclerosis	Multiple Sclerosis	Dietary Supplement: Lipoic Acid	Portland VA Medical Center	Oregon Health and Science University	Completed	18 Years	N/A	All	69	Phase 1	United States
7	NCT00676156 (ClinicalTrials.gov)	December 2005	7/5/2008	A Study of the Pharmacokinetics and Immunologic Effects of Lipoic Acid in Multiple Sclerosis	A Pilot Trial to Study the Pharmacokinetics of Oral Lipoic Acid(LA) and Immunological Effects of LA ...	Multiple Sclerosis	Drug: oral lipoic acid(LA);Drug: lipoic acid (LA) with fish oil and LA without fish oil;Drug: R lipoi ...	Oregon Health and Science University	National Center for Complementary and Integrative Health (NCCIH)	Completed	18 Years	80 Years	Both	40	Phase 1	United States
8	NCT00010842 (ClinicalTrials.gov)	September 1999	2/2/2001	Natural Antioxidants in the Treatment of Multiple Sclerosis	Natural Antioxidants in the Treatment of Multiple Sclerosis	Multiple Sclerosis	Drug: Ginkgo biloba;Drug: Alpha-lipoic acid;Drug: Vitamin E/Selenium;Drug: Essential fatty acids	National Center for Complementary and Integrative Health (NCCIH)	NULL	Completed	N/A	N/A	Both		Phase 1/Phase 2	United States

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