Disease details

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

10 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03424733 (ClinicalTrials.gov)	September 25, 2017	31/1/2018	Evaluating the Use of Prednisone to Decrease Pegylated Interferon Beta-1a Side Effects	A Trial of Prednisone and Acetaminophen Versus Acetaminophen Alone in Minimizing Flu-like Symptoms From Pegylated Interferon Beta-1a	Multiple Sclerosis	Drug: Plegridy;Drug: Prednisone;Drug: Tylenol Pill	Holy Name Medical Center, Inc.	Biogen	Recruiting	18 Years	N/A	All	50	Phase 4	United States
2	NCT02784210 (ClinicalTrials.gov)	October 5, 2016	26/5/2016	Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques	The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded Study	Multiple Sclerosis	Drug: Methylprednisolone;Drug: Prednisone	National Institute of Neurological Disorders and Stroke (NINDS)	NULL	Recruiting	18 Years	N/A	All	30	Phase 2	United States
3	NCT02809079 (ClinicalTrials.gov)	January 2016	12/6/2016	Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients	Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients	Neuromyelitis Optica Spectrum Disorders;Mycophenolate Mofetil;Efficacy and Safety	Drug: Mycophenolate mofetil;Drug: Prednisone	Third Affiliated Hospital, Sun Yat-Sen University	Zhongshan Ophthalmic Centre, Sun Yat-sen University;Nangfang Hospital, Southern Medical University	Enrolling by invitation	18 Years	65 Years	Both	100	Phase 4	NULL
4	NCT01411514 (ClinicalTrials.gov)	August 2011	26/5/2011	Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis	Phase IV Study of Oral Prednisone Taper vs. Placebo Following Intravenous Steroids for the Treatment of Acute Relapses in Multiple Sclerosis Within the Ticino Cohort	Multiple Sclerosis	Drug: Prednisone;Drug: Placebo	Claudio Gobbi	Ente Ospedaliero Cantonale, Ticino, Switzerland	Terminated	18 Years	80 Years	Both	27	Phase 4	Switzerland
5	NCT00716066 (ClinicalTrials.gov)	June 2008	15/7/2008	Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases	High-Dose Immunosuppressive Therapy Using Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) + Thymoglobulin Followed by Syngeneic or Autologous Hematopoietic Cell Transplantation for Patients With Autoimmune Neurologic Diseases	Autoimmune Disease;Neurologic Autoimmune Disease;Autologous Transplant Autoimmune;Multiple Sclerosis Transplant;MS Stem Cell Transplant;Multiple Sclerosis Stem Cell Transplant;Stiff Person Syndrome;HCT for Neurologic Autoimmune Disorders;CIDP Transplant;Myasthenia Gravis Transplant;Autoimmune Nervous System Disorder;Central Nervous System Vasculitis;Cerebellar Degeneration;Chronic Inflammatory Demyelinating Polyneuropathy;Lambert Eaton Myasthenic Syndrome;Myasthenia Gravis;Neuromyelitis Optica;Opsoclonus Myoclonus Syndrome;Rasmussen Subacute Encephalitis	Biological: Anti-Thymocyte Globulin;Procedure: Autologous Hematopoietic Stem Cell Transplantation;Drug: Carmustine;Drug: Cytarabine;Drug: Etoposide;Other: Laboratory Biomarker Analysis;Drug: Melphalan;Procedure: Peripheral Blood Stem Cell Transplantation;Drug: Prednisone;Procedure: Syngeneic Bone Marrow Transplantation	Fred Hutchinson Cancer Research Center	NULL	Recruiting	N/A	71 Years	All	40	Phase 2	United States
6	NCT00288626 (ClinicalTrials.gov)	July 2006	7/2/2006	High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study	A Phase II Study of High-Dose Immunosuppressive Therapy Using Carmustine, Etoposide, Cytarabine, Melphalan, Thymoglobulin and Autologous CD34+ Hematopoietic Stem Cell Transplant for the Treatment of Poor Prognosis Multiple Sclerosis	Relapsing-Remitting Multiple Sclerosis	Drug: Granulocyte-colony stimulating factor (G-CSF) and prednisone;Drug: Carmustine , etoposide, cytarabine, and melphalan (BEAM);Procedure: Autologous hematopoietic stem cell transplant	National Institute of Allergy and Infectious Diseases (NIAID)	Immune Tolerance Network (ITN)	Completed	18 Years	60 Years	All	25	Phase 2	United States
7	NCT00203047 (ClinicalTrials.gov)	January 2005	13/9/2005	Assessment Study of Steroid Effect in Relapsing Multiple Sclerosis Subjects Treated With Glatiramer Acetate	A Multi-Centered, Randomized, Double-Blind, Placebo Controlled Study Assessing the Add-on Effect of Oral Steroids in Relapsing Remitting Multiple Sclerosis Subjects Treated With Glatiramer Acetate (GA)	Relapsing Remitting Multiple Sclerosis	Drug: Glatiramer Acetate;Drug: Placebo;Drug: Prednisone	Teva Pharmaceutical Industries	NULL	Terminated	18 Years	55 Years	All	414	Phase 4	Canada;United States
8	NCT00014755 (ClinicalTrials.gov)	December 1997	10/4/2001	Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple Sclerosis		Multiple Sclerosis	Drug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: filgrastim;Drug: prednisone;Procedure: peripheral blood stem cell transplantation;Procedure: irradiation	Fred Hutchinson Cancer Research Center	NULL	Completed	18 Years	60 Years	Both	35	Phase 1	United States
9	NCT00000147 (ClinicalTrials.gov)	July 1988	23/9/1999	Longitudinal Optic Neuritis Study (LONS)		Multiple Sclerosis;Optic Neuritis	Drug: Methylprednisolone;Drug: Prednisone	National Eye Institute (NEI)	NULL	Active, not recruiting	18 Years	46 Years	Both		N/A	United States
10	NCT00000146 (ClinicalTrials.gov)	July 1988	23/9/1999	Optic Neuritis Treatment Trial (ONTT)		Multiple Sclerosis;Optic Neuritis	Drug: Methylprednisolone;Drug: Prednisone	National Eye Institute (NEI)	NULL	Active, not recruiting	18 Years	46 Years	Both		Phase 3	United States

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