162. 類天疱瘡（後天性表皮水疱症を含む。） Pemphigoid Clinical trials / Disease details

臨床試験数 : 83 / 薬物数 : 128 - (DrugBank : 51) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 142

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04128176 (ClinicalTrials.gov)	May 25, 2023	12/10/2019	Efficacy and Safety of Rituximab Combined With Omalizumab in Patients With Bullous Pemphigoid	An Open-Label Study to Evaluate the Efficacy and Safety of Rituximab Combined With Omalizumab in Pat ...	Bullous Pemphigoid	Drug: Rituximab combined with Omalizumab	University of California, Davis	NULL	Not yet recruiting	18 Years	90 Years	All	15	Phase 3	United States
2	NCT05267600 (ClinicalTrials.gov)	March 2022	14/2/2022	A Phase 2/3 Study of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid (BALLAD)	A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Investigate the ...	Bullous Pemphigoid	Biological: EFG PH20 SC;Other: PBO;Drug: Prednisone	argenx	NULL	Not yet recruiting	18 Years	N/A	All	160	Phase 2/Phase 3	NULL
3	NCT05263505 (ClinicalTrials.gov)	February 21, 2022	16/2/2022	Baricitinib for the Treatment of Ocular Mucous Membrane Pemphigoid	Baricitinib for the Treatment of Ocular Mucous Membrane Pemphigoid	Mucous Membrane Pemphigoid;Cicatrizing Conjunctivitis	Drug: Baricitinib 2 MG [Olumiant];Drug: Methotrexate;Drug: Azathioprine;Drug: Mycophenolate	Washington University School of Medicine	Eli Lilly and Company	Recruiting	18 Years	N/A	All	20	Phase 2	United States
4	EUCTR2020-005987-67-DE (EUCTR)	22/12/2021	16/07/2021	A study to see if 24-weeks of treatment with nomacopan works and is safe in adult patients with bull ...	A randomized, part A partial blinded and part B double blinded, placebo-controlled 24-week clinical ...	moderate to severe bullous pemphigoid MedDRA version: 21.1;Level: LLT;Classification code 10006567;T ...	Product Name: nomacopan Product Code: rVA576 INN or Proposed INN: NOMACOPAN Other descriptive name: rVA ...	Akari Therapeutics Plc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	48	Phase 3	United States;Germany
5	EUCTR2020-000287-32-GR (EUCTR)	04/11/2021	13/09/2021	A study to investigate the use of benralizumab in patients with bullous pemphigoid	A Multinational, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Investigate t ...	Bullous Pemphigoid MedDRA version: 21.1;Level: LLT;Classification code 10006567;Term: Bullous pemphi ...	Trade Name: Fasenra Product Name: benralizumab Product Code: MEDI-563 INN or Proposed INN: benralizumab ...	AstraZeneca AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	120	Phase 3	France;United States;Greece;Spain;Australia;Bulgaria;Israel;Germany;Italy;Japan;China
6	NCT05061771 (ClinicalTrials.gov)	September 2021	15/9/2021	Nomacopan Therapy in Adult Patients With Bullous PemphigoidReceiving Adjunct Oral Corticosteroid The ...	A Randomized, Part A Partial Blinded and Part B Double Blinded, Placebo-controlled 24-week Clinical ...	Bullous Pemphigoid	Drug: nomacopan (rVA576);Other: Placebo	AKARI Therapeutics	NULL	Not yet recruiting	18 Years	99 Years	All	148	Phase 3	NULL
7	EUCTR2020-000287-32-DE (EUCTR)	12/04/2021	16/10/2020	A study to investigate the use of benralizumab in patients with bullous pemphigoid	A Multinational, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Investigate t ...	Bullous Pemphigoid MedDRA version: 21.1;Level: LLT;Classification code 10006567;Term: Bullous pemphi ...	Trade Name: Fasenra Product Name: benralizumab Product Code: MEDI-563 INN or Proposed INN: benralizumab ...	AstraZeneca AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	120	Phase 3	United States;France;Greece;Spain;Australia;Israel;Bulgaria;Germany;Japan;Italy;China
8	NCT04612790 (ClinicalTrials.gov)	March 31, 2021	12/10/2020	A Study to Investigate the Use of Benralizumab in Patients With Bullous Pemphigoid.	A Multinational, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Investigate t ...	Bullous Pemphigoid	Biological: Benralizumab;Biological: Placebo	AstraZeneca	NULL	Recruiting	18 Years	130 Years	All	120	Phase 3	United States;Australia;Bulgaria;China;France;Germany;Greece;Israel;Italy;Japan;Spain
9	NCT04776694 (ClinicalTrials.gov)	March 29, 2021	25/2/2021	Compassionate Use of Dupilumab		Bullous Pemphigoid;Eosinophilic Esophagitis (EoE);Pediatric Asthma;Pediatric and Adolescent Chronic ...	Drug: Dupilumab	Regeneron Pharmaceuticals	NULL	Available						NULL
10	JPRN-jRCT2071210014	26/03/2021	26/04/2021	A Multinational, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Investigate t ...	The purpose of this study is to investigate the use of benralizumab is effective in the treatment of ...	Bullous Pemphigoid	This study is designed to assess the efficacy and safety of a benralizumab60 mg loading dose followe ...	Hibi Kazushige	NULL	Recruiting	>= 18age old	Not applicable	Both	12	Phase 3	United States;Australia;Bulgaria;France;Germany;Israel;Italy;Spain;Japan

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