167. マルファン症候群 Marfan syndrome Clinical trials / Disease details

臨床試験数 : 20 / 薬物数 : 39 - (DrugBank : 10) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 50

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04970459 (ClinicalTrials.gov)	January 25, 2022	9/7/2021	Biological Collection for Marfan and Related Syndromes	Constitution of a Biological Collection to Study the Pathophysiology in Marfan Syndromeand Related S ...	Marfan Syndrome	Biological: collection of samples of blood and urine	University Hospital, Toulouse	NULL	Not yet recruiting	3 Years	99 Years	All	300		France
2	NCT01949233 (ClinicalTrials.gov)	October 2013	6/8/2013	The Oxford Marfan Trial	A Randomised, Double-blind, Placebo-controlled Pilot Trial of Irbesartan, Doxycycline and a Combinat ...	Marfan Syndrome	Drug: Irbesartan 150-300mg capsules daily for 6 months;Drug: Doxycycline 100-200mg capsules daily for ...	University of Oxford	Oxford University Hospitals NHS Trust	Recruiting	13 Years	N/A	Both	56	Phase 2	United Kingdom
3	EUCTR2010-023612-14-GB (EUCTR)	08/03/2013	20/12/2012	The Oxford Marfan Trial	A randomised, double-blind, placebo-controlled pilot trial of irbesartan, doxycycline and a combinat ...	Marfan syndrome. MedDRA version: 14.1;Level: PT;Classification code 10026829;Term: Marfan's syndrome ...	Trade Name: Aprovel Product Name: Aprovel INN or Proposed INN: Irbesartan Trade Name: Vibrox 100mg Capsu ...	Clinical Trials and Research Governance	NULL	Not Recruiting			Female: yes Male: yes	56	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United Kingdom
4	EUCTR2010-019302-16-GB (EUCTR)	13/09/2010	17/08/2010	A prospective, randomised, placebo-controlled, double blind, multi-centre study of the effects of Ir ...	A prospective, randomised, placebo-controlled, double blind, multi-centre study of the effects of Ir ...	Marfan Syndrome	Trade Name: Aprovel Product Name: Aprovel INN or Proposed INN: Irbesartan INN or Proposed INN: Irbesart ...	Royal Brompton and Harefield NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes	490	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom
5	NCT01715207 (ClinicalTrials.gov)	June 2010	24/10/2012	Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS	Comparison Study of the Effect of Aliskiren Versus Negative Controls on Aortic Stiffness in Patients ...	Marfan Syndrome	Drug: Aliskiren;Drug: Atenolol	Samsung Medical Center	NULL	Completed	14 Years	55 Years	All	30	Phase 3	Korea, Republic of
6	NCT00782327 (ClinicalTrials.gov)	June 2009	29/10/2008	Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic ...	Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic ...	Marfan Syndrome	Drug: Losartan;Drug: Placebo	University Hospital, Ghent	Agentschap voor Innovatie door Wetenschap en Technologie	Recruiting	10 Years	N/A	Both	174	Phase 3	Belgium
7	EUCTR2007-005862-10-BE (EUCTR)	29/05/2009	07/01/2009	Randomized, double-blind study for the evaluation of the effect of losartan versus placebo on aortic ...	Randomized, double-blind study for the evaluation of the effect of losartan versus placebo on aortic ...	Marfan syndrome MedDRA version: 9.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome	Trade Name: Cozaar Product Name: Losartan INN or Proposed INN: Losartan potassium Trade Name: Coozar Prod ...	University Hospital Ghent	NULL	Not Recruiting			Female: yes Male: yes			Belgium
8	EUCTR2008-001462-81-IT (EUCTR)	27/10/2008	17/03/2008	Effects of Losartan versus Nebivolol versus the association of both on the progression of aortic roo ...	Effects of Losartan versus Nebivolol versus the association of both on the progression of aortic roo ...	Marfan Syndrome MedDRA version: 9.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome	Trade Name: LORTAAN 28CPR RIV DIV 50MG INN or Proposed INN: Losartan Trade Name: LOBIVON 28CPR 5MG INN ...	OSPEDALE POLICLINICO S. MATTEO	NULL	Not Recruiting			Female: yes Male: yes		Phase 3	Italy
9	NCT01145612 (ClinicalTrials.gov)	October 2008	15/6/2010	Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome	A Clinical Trial to Assess the Efficacy and Safety of Losartan Versus Atenolol in the Prevention of ...	Marfan Syndrome	Drug: Losartan;Drug: Atenolol	Forteza, Albert, M.D.	Ministry of Health, Spain	Active, not recruiting	5 Years	60 Years	Both	140	Phase 3	Spain
10	NCT00763893 (ClinicalTrials.gov)	September 2008	30/9/2008	Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome	Multicenter, Randomised, Double Blind Study of the Efficacy of Losartan on Aortic Dilatation in Pati ...	Marfan Syndrome	Drug: placebo;Drug: Losartan	Assistance Publique - Hôpitaux de Paris	NULL	Terminated	10 Years	N/A	Both	303	Phase 3	France

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