17. 多系統萎縮症 Multiple system atrophy Clinical trials / Disease details
臨床試験数 : 118 / 薬物数 : 163 - (DrugBank : 49) / 標的遺伝子数 : 61 - 標的パスウェイ数 : 112
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04782830 (ClinicalTrials.gov) | February 5, 2021 | 1/3/2021 | Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms | Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms | Orthostatic; Hypotension, Neurogenic;Autonomic Failure;Pure Autonomic Failure;Multiple System Atrophy; Hypotension, Parkinsonism | Device: Accelerometer;Drug: placebo pill;Drug: Midodrine or atomoxetine pill | Vanderbilt University Medical Center | NULL | Recruiting | 40 Years | 80 Years | All | 29 | N/A | United States |
| 2 | NCT04620382 (ClinicalTrials.gov) | November 9, 2020 | 27/10/2020 | Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients | Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients | Neurogenic Orthostatic Hypotension;Autonomic Failure;Pure Autonomic Failure;Multiple System Atrophy;Parkinson Disease | Drug: Midodrine;Drug: Placebo pill;Device: Abdominal compression;Device: sham compression | Vanderbilt University Medical Center | National Heart, Lung, and Blood Institute (NHLBI) | Recruiting | 40 Years | 80 Years | All | 31 | Early Phase 1 | United States |
| 3 | NCT03482297 (ClinicalTrials.gov) | March 1, 2018 | 22/3/2018 | Automated Abdominal Binder for Orthostatic Hypotension | Randomized, Double-blind, Sham-controlled to Evaluate the Effects of an Automated Abdominal Binder in Improving Orthostatic Tolerance in Autonomic Failure Patients With Disabling Orthostatic Hypotension | Orthostatic Hypotension;Autonomic Failure;Pure Autonomic Failure;Multiple System Atrophy | Device: automated abdominal binder;Device: Sham binder;Drug: Placebo;Drug: Midodrine | Vanderbilt University Medical Center | National Heart, Lung, and Blood Institute (NHLBI) | Recruiting | 40 Years | 80 Years | All | 31 | Phase 1/Phase 2 | United States |
| 4 | NCT02897063 (ClinicalTrials.gov) | September 2016 | 7/9/2016 | Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure | The Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure Aim 2 of RDCRN (Rare Diseases Clinical Research Network) Project 2 | Autonomic Failure;Pure Autonomic Failure;Multiple System Atrophy;Parkinson Disease;Orthostatic Hypotension | Drug: Droxidopa;Drug: Midodrine;Drug: Placebo | Vanderbilt University Medical Center | NULL | Recruiting | 40 Years | 80 Years | All | 34 | Phase 1 | United States |
| 5 | NCT02429557 (ClinicalTrials.gov) | April 2015 | 21/4/2015 | Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure | Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure | Orthostatic Hypotension;Pure Autonomic Failure;Multiple System Atrophy;Autonomic Failure | Other: Abdominal compression;Other: Sham abdominal compression;Drug: Placebo pill;Drug: midodrine | Vanderbilt University Medical Center | National Heart, Lung, and Blood Institute (NHLBI) | Recruiting | 18 Years | 80 Years | All | 29 | Phase 1 | United States |