191. ウェルナー症候群 Werner syndrome Clinical trials / Disease details
臨床試験数 : 3 / 薬物数 : 4 - (DrugBank : 3) / 標的遺伝子数 : 1 - 標的パスウェイ数 : 5
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | JPRN-jRCTs031190141 | 19/03/2021 | 27/11/2019 | Cross-over trial to verify safety and effectiveness of nicotinamide riboside for patients with Werner syndrome | Prospective, single-center, cross-over trial to verify safety and effectiveness of nicotinamide riboside for patients with Werner syndrome - EMPOWER | Werner syndrome Werner syndrome;C16.320.925 / C18.452.284.960 | Subjects ingest oral capsules of NR (nicotinamide riboside) once daily (total daily dose: nicotinamide riboside 1000 mg). | Yokote Koutaro | NULL | Recruiting | >= 20age old | Not applicable | Both | 30 | Phase 1-2 | Japan |
2 | NCT04512963 (ClinicalTrials.gov) | August 24, 2020 | 6/8/2020 | Phase I Study of Progerinin in Healthy Volunteers | A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose (SAD) Study Including a Food Interaction Study, Followed by a Multiple Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Profile of Progerinin in Healthy Volunteers | Hutchinson-Gilford Progeria Syndrome;Werner Syndrome | Drug: Progerinin;Drug: Placebo | PRG Science & Technology Co., Ltd. | Amarex Clinical Research | Completed | 18 Years | 45 Years | All | 64 | Phase 1 | United States |
3 | NCT00004815 (ClinicalTrials.gov) | May 1992 | 24/2/2000 | Descriptive Study of Recombinant Human Insulin-Like Growth Factor for Osteoporosis in Werner's Syndrome | Werner's Syndrome | Drug: growth hormone | National Center for Research Resources (NCRR) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS);University of Texas | Completed | N/A | N/A | Both | 1 | N/A | NULL |