DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
2. 筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
Clinical trials
/
Disease details
臨床試験数
:
624
/
薬物数
:
611
- (
DrugBank
:
160
) /
標的遺伝子数
:
172
-
標的パスウェイ数
:
225
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Phase
Countries
1
NCT02962050
(
ClinicalTrials.gov
)
May 31, 2017
4/11/2016
Delineating Swallowing Impairment and Decline in ALS
Delineating Physiologic Mechanisms of Swallowing Impairment and Decline in ALS
Amyotrophic Lateral Sclerosis
Procedure:
Videofluoroscopic Swallowing Study (VFSS)
;Device:
Voluntary Peak Cough Flow Testing
;Device:
Iowa Oral Performance Instrument
;Drug:
Capsaicin
Challenge
;Device:
Pulmonary Function Testing
;
Other: Eating Assessment Tool 10
;
Other: The Center for Neurologic Study Bulbar Function Scale
Procedure:
Videofluoroscopic Swallowing Study (VFSS)
;Device:
Voluntary Peak Cough Flow Testing
;Devic ...
University of Florida
National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting
18 Years
90 Years
All
110
United States
2
NCT02710110
(
ClinicalTrials.gov
)
April 2016
26/2/2016
Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS)
The Impact of Respiratory Strength Training in Individuals With Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
Device:
PowerLung trainer
;Device:
Micro Mouth Pressure Meter
;Procedure:
Pulmonary Function Testing
;Procedure:
Videofluoroscopic swallowing study
;
Other: Swallowing Quality of Life Questionnaire
;Device:
Iowa Oral Pressure Instrument
;Drug:
Capsaicin
Device:
PowerLung trainer
;Device:
Micro Mouth Pressure Meter
;Procedure:
Pulmonary Function Testing
;P ...
University of Florida
ALS Association
Completed
21 Years
85 Years
All
50
Early Phase 1
United States
3
NCT02710162
(
ClinicalTrials.gov
)
April 2016
29/2/2016
Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
Determination of Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
Device:
Micro Mouth Pressure Meter
;Device:
Iowa Oral Performance Instrument
;Device:
Electrical Impedance Myography
;Drug:
Capsaicin
;Procedure:
Videofluoroscopic Swallowing Study
;Procedure:
Pulmonary Function Testing
;
Other: Swallowing Related Quality of Life Questionnaire
;
Other: Functional Oral Intake Scale
;
Other: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised
;
Other: Eating Assessment Tool-10
;
Other: Communicative Effectiveness Survey
;
Other: The Center for Neurologic Studies Bulbar Function Scale
Device:
Micro Mouth Pressure Meter
;Device:
Iowa Oral Performance Instrument
;Device:
Electrical Imped
...
University of Florida
NULL
Completed
21 Years
85 Years
All
21
Early Phase 1
United States