2. 筋萎縮性側索硬化症 Amyotrophic lateral sclerosis Clinical trials / Disease details


臨床試験数 : 624 薬物数 : 611 - (DrugBank : 160) / 標的遺伝子数 : 172 - 標的パスウェイ数 : 225

  
9 trials found
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PhaseCountries
1NCT00982150
(ClinicalTrials.gov)
September 200922/9/2009Extension Study of Talampanel for Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Open Label Phase to Assess Tolerability and Safety of Talampanel 50mg Tid in Subjects With Amyotrophic Lateral Sclerosis (ALS)Amyotrophic Lateral SclerosisDrug: TalampanelTeva Pharmaceutical IndustriesNULLTerminated18 Years80 YearsBoth446Phase 2United States;Belgium;Canada;France;Germany;Hungary;Israel;Italy;Netherlands;Spain
2EUCTR2008-002062-62-NL
(EUCTR)
14/10/200802/06/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
3EUCTR2008-002062-62-FR
(EUCTR)
22/09/200819/06/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Phase 2France;Hungary;Belgium;Spain;Germany;Netherlands;Italy
4EUCTR2008-002062-62-HU
(EUCTR)
17/09/200817/12/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS).A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
5EUCTR2008-002062-62-DE
(EUCTR)
08/09/200819/01/2009A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). - ALSTARA Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). - ALSTAR Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
6NCT00696332
(ClinicalTrials.gov)
September 200810/6/2008Talampanel for Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of Talampanel in Subjects With Amyotrophic Lateral Sclerosis (ALS)ALSDrug: Talampanel;Other: placeboTeva Pharmaceutical IndustriesNULLCompleted18 Years80 YearsBoth559Phase 2United States;Belgium;Canada;France;Germany;Hungary;Israel;Italy;Netherlands;Spain
7EUCTR2008-002062-62-ES
(EUCTR)
13/08/200826/06/2008Estudio multinacional, multicéntrico, randomizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia, tolerabilidad y seguridad de Talampanel en pacientes con Esclerosis Lateral Amiotrófica (ELA)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS)Estudio multinacional, multicéntrico, randomizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia, tolerabilidad y seguridad de Talampanel en pacientes con Esclerosis Lateral Amiotrófica (ELA)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) Esclerosis Lateral Amiotrófica (ELA).Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Phase 2France;Hungary;Belgium;Spain;Germany;Netherlands;Italy
8EUCTR2008-002062-62-BE
(EUCTR)
31/07/200811/07/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS).A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
9EUCTR2008-002062-62-IT
(EUCTR)
16/06/200827/06/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) - ALSTARA Multinational, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) - ALSTAR Amyotrophic Lateral Sclerosis
MedDRA version: 9.1;Level: LLT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: tallampanel
Product Code: TV-7110
Product Name: talampanel
Teva Pharmaceutical Industries,LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy