205. 脆弱Ｘ症候群関連疾患 Fragile X syndrome related disease Clinical trials / Disease details

臨床試験数 : 5 / 薬物数 : 13 - (DrugBank : 7) / 標的遺伝子数 : 25 - 標的パスウェイ数 : 29

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05233579 (ClinicalTrials.gov)	June 25, 2021	20/10/2021	Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS	Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS to Find Biomarkers	Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis)	Dietary Supplement: Sulforaphane	University of California, Davis	NULL	Recruiting	50 Years	85 Years	All	15	N/A	United States
2	NCT02603926 (ClinicalTrials.gov)	October 2015	5/11/2015	Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone	Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone	Fragile X-associated Tremor/Ataxia Syndrome	Drug: Allopregnanolone	Randi J. Hagerman, MD	NULL	Completed	50 Years	85 Years	All	6	Phase 2	United States
3	NCT02197104 (ClinicalTrials.gov)	January 2015	14/7/2014	Citocoline for Treatment of FXTAS	Phase 2 Study of Citocoline for Treatment in Fragile X-associated Tremor/Ataxia Syndrome	Balance and Cognitive Deficits in Fragile X-associated Tremor Ataxia Syndrome	Drug: citocoline	Rush University Medical Center	NULL	Completed	18 Years	90 Years	All	10	Phase 2	United States
4	NCT00584948 (ClinicalTrials.gov)	September 2007	22/12/2007	Memantine Treatment in Fragile X-Associated Tremor/Ataxia Syndrome	Characterization and Treatment of CNS Abnormalities in Premutation Carriers: A Double-Blind Placebo- ...	Fragile X-Associated Tremor/Ataxia Syndrome;Fragile X Premutation Carriers	Drug: Memantine;Drug: Placebo	University of California, Davis	National Institute on Aging (NIA);Forest Laboratories	Completed	30 Years	80 Years	All	94	N/A	United States
5	NCT00033293 (ClinicalTrials.gov)	March 15, 2004	9/4/2002	Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement ...	A Pilot Study Randomized Trial of Intravenous Gammaglobulin Therapy for Patients With Neuroblastoma ...	Disseminated Neuroblastoma;Localized Resectable Neuroblastoma;Localized Unresectable Neuroblastoma;R ...	Biological: therapeutic immune globulin;Other: clinical observation;Drug: cyclophosphamide;Drug: pre ...	Children's Oncology Group	National Cancer Institute (NCI)	Active, not recruiting	N/A	8 Years	All	53	Phase 3	United States;Australia;Canada;Netherlands;New Zealand;Puerto Rico;Switzerland

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