210. 単心室症 Single Ventricle Clinical trials / Disease details

臨床試験数 : 49 / 薬物数 : 53 - (DrugBank : 23) / 標的遺伝子数 : 32 - 標的パスウェイ数 : 67

4 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01292551 (ClinicalTrials.gov)	February 2011	8/2/2011	Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology.	Treatment With Endothelin Antagonist to Tcpc Patients; a Multicenter, Randomized, Prospective Study ...	Hypoplastic Left Heart Syndrome;Tricuspid Atresia;Other Specified Congenital Anomalies of Heart	Drug: Bosentan;Drug: Placebo	Rigshospitalet, Denmark	Aarhus University Hospital;Bispebjerg Hospital;Actelion	Completed	15 Years	N/A	Both	75	Phase 2	Denmark;Sweden
2	NCT00989911 (ClinicalTrials.gov)	May 2010	5/10/2009	Endothelin Blockade in Patients With Single Ventricle Physiology	Endothelin Blockade in Patients With Single Ventricle Physiology	Congenital Heart Disease	Drug: Bosentan	University of California, Los Angeles	Actelion	Completed	12 Years	N/A	All	10	N/A	United States
3	NCT01662037 (ClinicalTrials.gov)	January 2010	5/8/2012	Bosentan Therapy in Children With Functional Single Ventricle	Bosentan Therapy for High Risk Staged Fontan Procedure in Children With Functional Single Ventricle	Congenital Heart Defects;Functional Single Ventricle	Drug: Bosentan	Shanghai Jiao Tong University School of Medicine	NULL	Completed	4 Months	18 Years	Both	34	Phase 2	China
4	EUCTR2005-005898-29-GB (EUCTR)	04/07/2008	09/05/2008	The effect of bosentan, a selective endothelin antagonist, on cardiovascular performance in patients ...	The effect of bosentan, a selective endothelin antagonist, on cardiovascular performance in patients ...	Patients with a Fontan circulation (that is they have had a Fontan operation for a functionally univ ...	Trade Name: Tracleer Product Name: bosentan INN or Proposed INN: Bosentan INN or Proposed INN: Bosentan ...	University Hospital Birmingham	NULL	Not Recruiting			Female: yes Male: yes	15	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom

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