215. ファロー四徴症 Tetralogy of Fallot Clinical trials / Disease details

臨床試験数 : 22 / 薬物数 : 48 - (DrugBank : 19) / 標的遺伝子数 : 18 - 標的パスウェイ数 : 49

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04713657 (ClinicalTrials.gov)	March 30, 2022	13/1/2021	Beta-blocker Administration for Cardiomyocyte Division	Mechanistic Clinical Trial of Beta-Blocker Administration For Reactivating Cardiomyocyte Division In ...	Tetralogy of Fallot	Other: N-thymidine;Other: Urine Collection;Procedure: Echocardiogram;Procedure: Cardiac MRI;Drug: Pr ...	Bernhard Kuhn	University of Pittsburgh	Not yet recruiting	N/A	2 Months	All	40	Phase 1	United States
2	NCT05186415 (ClinicalTrials.gov)	January 2022	20/12/2021	Contrast Enhanced Three Dimensional Echocardiographic Quantification of Right Ventricular Volumes in ...	Contrast Enhanced Three Dimensional Echocardiographic Quantification of Right Ventricular Volumes in ...	Tetralogy of Fallot	Drug: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]	Nemours Children's Health System	Thomas Jefferson University	Not yet recruiting	11 Years	N/A	All	60	Phase 1/Phase 2	NULL
3	NCT05176782 (ClinicalTrials.gov)	December 15, 2021	15/12/2021	Comparison Between Histidine-tryptophan-ketoglutarate Cardioplegia and Cold Blood Cardioplegia for M ...	Randomized Clinical Trial: Comparison Between Histidine-tryptophan-ketoglutarate Cardioplegia and Co ...	Anesthesia	Drug: HTK cardioplegia;Drug: Cold Cadioplegia	Ain Shams University	NULL	Recruiting	6 Months	5 Years	All	52	Early Phase 1	Egypt
4	ChiCTR2000033234	2020-06-05	2020-05-25	Comprehensive study for surgical effect and prognosis of Tetralogy of Fallot	A single-center ambispective cohort study for surgical effect and prognostic factors of Tetralogy of ...	Tetralogy of Fallot	TOF AS:annlus-sparing repair;TOF TAPE:transannular patch enlargement;	Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and ...	NULL	Pending			Both	TOF AS:247;TOF TAPE:247;	N/A	China
5	NCT04017975 (ClinicalTrials.gov)	December 20, 2019	10/7/2019	Optical Tissue Identification for Myocardial Architecture	Optical Tissue Identification for Myocardial Architecture (OPTIMA Study)	Ventricular Septal Defect;Complete Atrioventricular Canal;Tetralogy of FallotWith Pulmonary Stenosis ...	Drug: Fluorescite;Device: Cellvizio 100 Series System with Confocal Miniprobes	Aditya Kaza	National Heart, Lung, and Blood Institute (NHLBI)	Recruiting	N/A	18 Years	All	70	Phase 2	United States
6	ChiCTR1900025513	2019-09-01	2019-08-31	The safety and efficacy of preoperative oral supplementation of coenzyme Q10 in improving postoperat ...	The safety and efficacy of preoperative oral supplementation of coenzyme Q10 in improving postoperat ...	tetralogy of fallot (pulmonary atresia)	01:N/A ;02:Oral coenzyme Q10, 2.5mg, t.i.d.;03:Oral coenzyme Q10, 5mg, t.i.d.;04:Oral coenzyme Q10, ...	Fuwai Central China Cardiovascualr Hospital	NULL	Pending	0	2	Both	01:8;02:8;03:8;04:8;05:8;		China
7	ChiCTR1800019578	2018-12-01	2018-11-18	Effects of different tranexamic acid regimen in cyanotic pediatric cardiac surgery	Effects of different tranexamic acid regimen in cyanotic pediatric cardiac surgery	Tetralogy of Fallot	Conventional treatment group:Childen did not receive an antifibrinolytic agent during surgery;Low do ...	National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and ...	NULL	Pending			Both	Conventional treatment group:225;Low dose of tranexamic acid group:225;High dose of tranexamic acid group:225;		China
8	NCT03835494 (ClinicalTrials.gov)	November 1, 2018	8/1/2019	Analysis of RV-Dysfunction in Fallot Patients	Tissue Doppler Imaging - A Promising Technique To Assess Myocardial Function In Adult Fallot Patient ...	Tetralogy of Fallot	Other: Transthoracic echocardiography at rest, during PLR, HG and CPX (including blood gas analysis ...	Klinik für Kardiologie, Pneumologie und Angiologie	NULL	Completed	18 Years	80 Years	All	60	N/A	Germany
9	NCT03732742 (ClinicalTrials.gov)	November 2018	22/10/2018	Comparison of Mid-term Results of Total Correction of TOF Between Preservation of PV and Trans-annul ...	Comparison of Mid-term Results of Total Correction of Tetralogy of FallotBetween Preservation of Pul ...	Tetrology of Fallot	Procedure: TOF repair with trans-annular patch VS preservation of PV	Assiut University	NULL	Unknown status	N/A	N/A	All	50	N/A	NULL
10	NCT03049995 (ClinicalTrials.gov)	November 2016	2/2/2017	Stress Echo 2020 - The International Stress Echo Study	The International Stress Echo Study in Ischemic and Non-ischemic Heart Disease	Coronary Artery Disease;Heart Failure;Hypertrophic Cardiomyopathy;Aortic Valve Disease;Athletes Hear ...	Procedure: Left ventricular contractile reserve SE;Procedure: B-lines SE;Procedure: Left ventricular ...	Fatebenefratelli Hospital	Institute of Clinical Physiology, CNR, Pisa,Italy;Salerno Hospital, Italy;Monaldi Hospital, Napoli, ...	Recruiting	18 Years	85 Years	All	300		Italy

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