22. もやもや病 Moyamoya disease Clinical trials / Disease details
臨床試験数 : 14 / 薬物数 : 21 - (DrugBank : 14) / 標的遺伝子数 : 28 - 標的パスウェイ数 : 44
Showing 1 to 10 of 14 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | ChiCTR2100046178 | 2021-05-10 | 2021-05-08 | Efficacy and safety of antiplatelet drugs in patients with moyamoya disease after revascularization | Efficacy and safety of antiplatelet drugs in patients with moyamoya disease after revascularization | Moyamoya disease | Taking aspirin group:Nil;No aspirin group:Nil; | Qilu Hospital of Shandong University | NULL | Recruiting | 0 | 60 | Both | Taking aspirin group:105;No aspirin group:105; | china | |
2 | JPRN-jRCTs031200402 | 23/04/2021 | 08/03/2021 | Search for abnormalities of fundus blood vessels in moyamoya disease | Search for abnormalities of fundus blood vessels in moyamoya disease | Moyamoya disease Moyamoya disease | For fluorescein fundus angiography, 500 mg of fluorescein (5 ml vial of aqueous solution containing 500 mg of fluorescein) and 25 mg of Ophthagreen (2 ml of blue indocyanine green) are dissolved in 2 ml of distilled water for injection and injected through the forearm of the elbow vein. In daily practice, diabetic retinopathy can be treated by using a diabetic retinal imaging system (optos). In daily practice, it is used for the diagnosis of diabetic retinopathy, uveitis, occlusive retinal vascular disease, and age-related macular degeneration. For fluoresceinfundus angiography, 500 mg of fluorescein(5 ml vial of aqueous solution containing 50 ... | Akiyama Hideo | NULL | Recruiting | >= 20age old | Not applicable | Both | 50 | N/A | Japan |
3 | ChiCTR2000041260 | 2021-01-01 | 2020-12-23 | The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative hypotension in STA-MCA bypass surgery The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative h ... | The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative hypotension in STA-MCA bypass surgery The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative h ... | moyamoya disease | Group 1:iv norepinephrine;Group 2:iv phenylephrine; | The South District of Anhui Provincial Hospital | NULL | Recruiting | 18 | 65 | Both | Group 1:30;Group 2:30; | Phase 4 | China |
4 | ChiCTR2000029878 | 2020-11-01 | 2020-02-16 | The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative hypotension in STA-MCA bypass surgery The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative h ... | The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative hypotension in STA-MCA bypass surgery The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative h ... | moyamoya disease | Group 1:iv norepinephrine;Group 2:iv phenylephrine; | The South District of Anhui Provincial Hospital | NULL | Pending | 18 | 65 | Both | Group 1:30;Group 2:30; | Phase 4 | China |
5 | NCT04205578 (ClinicalTrials.gov) | January 2020 | 18/12/2019 | NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events | A Multi-center, Randomized, Single-blind, Placebo-controlled Study of Dl-3-n-butylphthalide in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events After Extracranial-to-intracranial Revascularization Surgery A Multi-center, Randomized, Single-blind, Placebo-controlled Study of Dl-3-n-butylphthalide in Patie ... | Moyamoya Disease;Ischemic Cerebral Infarction;Ischemic Stroke;Ischemic Cerebrovascular Accident;Transient Ischemic Attack Moyamoya Disease;Ischemic Cerebral Infarction;Ischemic Stroke;Ischemic Cerebrovascular Accident;Tran ... | Drug: dl-3-n-butylphthalide (NBP);Drug: Normal Saline 0.9% Infusion Solution | yuanli Zhao | Peking University International Hospital | Not yet recruiting | 18 Years | 60 Years | All | 450 | Phase 3 | China |
6 | NCT04012268 (ClinicalTrials.gov) | July 15, 2019 | 3/7/2019 | The Safety and Efficacy of RIC on Adult Moyamoya Disease | The Safety and Effect of Remote Ischemic Conditioning on Adult Moyamoya Disease | Moyamoya Disease | Device: RIC;Drug: Aspirin | Capital Medical University | NULL | Completed | 18 Years | 60 Years | All | 30 | N/A | China |
7 | ChiCTR1900027197 | 2019-05-01 | 2019-11-04 | Study on the protective effect of desflurane combined with propofol on the brain of patients with moyamoya disease undergoing cerebral revascularization Study on the protective effect of desflurane combined with propofol on the brain of patients with mo ... | Study for the protective effect of desflurane on the brain of patients with moyamoya disease | Moyamoya disease | Group D:Desflurane for anesthesia maintenance;GroupP:Propofol;GroupPD:Desflurane and propofol; | The First Affiliated Hospital of Zhengzhou University | NULL | Completed | 20 | 65 | Both | Group D:30;GroupP:30;GroupPD:30; | Phase 4 | China |
8 | NCT03882060 (ClinicalTrials.gov) | April 8, 2019 | 12/3/2019 | Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patien ... | The Effect of Recombinant Human Erythropoietin on the Postoperative Neurologic Outcome in Pediatric Moyamoya Disease Patients - A Double Blind Randomized Controlled Trial The Effect of Recombinant Human Erythropoietin on the Postoperative Neurologic Outcome in Pediatric ... | Moyamoya Disease;Pediatrics;Cerebrovascular Disorders | Drug: erythropoietin;Drug: Normal saline | Seoul National University Hospital | NULL | Active, not recruiting | N/A | 18 Years | All | 60 | N/A | Korea, Republic of |
9 | ChiCTR1800020377 | 2019-01-01 | 2018-12-27 | Aspirin in Moyamoya Disease | The Clinical Benefit and Risk of Oral Aspirin for Moyamoya Disease | moyamoya disease | Case series:Aspirin; | Beijing Tiantan Hospital, Capital Medical University | NULL | Recruiting | 8 | 60 | Both | Case series:300; | China | |
10 | JPRN-jRCTs031180017 | 01/08/2018 | 07/09/2018 | Studies on the utility of simultaneous-multi-slice acquisition (SMS) dynamic susceptibility contrast-enhanced (DSC)MRI for the occulusive cerebrobascular disease Studies on the utility of simultaneous-multi-slice acquisition (SMS) dynamic susceptibility contrast ... | Studies on the utility of simultaneous-multi-slice acquisition (SMS) dynamic susceptibility contrast-enhanced (DSC)MRI for the occulusive cerebrobascular disease - SMS DSC-MRI study for the occulusive cerebrobascular disease Studies on the utility of simultaneous-multi-slice acquisition (SMS) dynamic susceptibility contrast ... | carotid artery stenosis, moyamoya disease | Intravenous administration of gadobutrol (Gadovist, Bayer Schering Pharma, Berlin, Germany) is administered in the supine position, and high speed DSC-MRI scan by using SMS acquisition (temporal resolution of 0.5s) is carried out at the same time as injection of the contrast agent with an acquisition time of 70sec. The quantitative and qualitative comparison between reference data set (0.5s) and additional data sets with temporal resolution of 1.0s, 1.5s, and 2.0s generated from the reference data set, is performed. Intravenous administration of gadobutrol(Gadovist, Bayer Schering Pharma, Berlin, Germany) is admini ... | Aoki Shigeki | Bayer Yakuhin, Ltd;Bayer Yakuhin, Ltd | Complete | >= 20age old | Not applicable | Both | 50 | N/A | Japan |