222. 一次性ネフローゼ症候群 Primary nephrotic syndrome Clinical trials / Disease details

臨床試験数 : 285 / 薬物数 : 285 - (DrugBank : 108) / 標的遺伝子数 : 62 - 標的パスウェイ数 : 191

41 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05050214 (ClinicalTrials.gov)	March 2022	9/9/2021	Obinutuzumab in Primary MN	Obinutuzumab for Primary Membranous Nephropathy: a Pilot Study in Patients With Rituximab-resistant ...	Membranous Nephropathy	Drug: Obinutuzumab	Mario Negri Institute for Pharmacological Research	Roche S.p.a	Not yet recruiting	18 Years	N/A	All	20	Phase 2	Italy
2	EUCTR2021-004864-81-IT (EUCTR)	17/12/2021	17/09/2021	Proposta di studio per valutare l’efficacia di Obinutuzumab, un anticorpo anti-CD20, in pazienti con ...	Proposta di studio per valutare l’efficacia di Obinutuzumab, un anticorpo anti-CD20, in pazienti con ...	PRIMARY MEMBRANOUS NEPHROPATHY MedDRA version: 21.1;Level: LLT;Classification code 10027170;Term: Me ...	Trade Name: GAZYVARO - 1000 MG - CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCIN ...	IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20	Phase 2	Italy
3	NCT04745728 (ClinicalTrials.gov)	April 14, 2021	4/2/2021	Different Immunosuppressive Treatment in iMN	Different Immunosuppressive Treatment in Idiopathic Membranous Nephropathy: a Prospective Cohort	Idiopathic Membranous Nephropathy	Drug: Prednisone;Drug: Cyclophosphamide;Drug: Rituximab	Peking Union Medical College Hospital	NULL	Recruiting	18 Years	80 Years	All	200	Phase 3	China
4	NCT04743739 (ClinicalTrials.gov)	April 14, 2021	30/1/2021	Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN	A Multicenter Randomized Controlled Trial of RituximabCombined With Cyclosporine Versus RituximabAlo ...	Idiopathic Membranous Nephropathy	Drug: Rituximab;Drug: cyclosporine	Peking Union Medical College Hospital	Beijing Tongren Hospital;Chinese Academy of Medical Sciences, Fuwai Hospital;The Luhe Teaching Hospi ...	Recruiting	18 Years	80 Years	All	126	Phase 3	China
5	ChiCTR2100042674	2021-01-18	2021-01-26	Standard dose Rituximab for membranous nephropathy: a multi-center prospective cohort study	Standard dose Rituximab for membranous nephropathy: a multi-center prospective cohort study	syndrome disease	experimental group:RTX treatment;	Jiangsu Province People's Hospital	NULL	Recruiting	18	75	Male	experimental group:65;	Phase 4	China
6	NCT03970577 (ClinicalTrials.gov)	July 29, 2020	15/4/2019	RItuximab From the FIRst Episode of Idiopathic Nephrotic Syndrome	RituximabFrom the First Episode of Minimal Change Nephrotic Syndrome for Preventing Relapse Risk in ...	Minimal Change Nephrotic Syndrome (MCNS)	Drug: Rituximab;Drug: Prednisone	Assistance Publique - Hôpitaux de Paris	NULL	Recruiting	18 Years	N/A	All	148	Phase 2	France
7	ChiCTR2000032523	2020-06-01	2020-05-01	Efficacy and safety of rituximabin the treatment of primary membranous nephropathy with type 2 diabe ...	Efficacy and safety of rituximabin the treatment of primary membranous nephropathy with type 2 diabe ...	membranous nephropathy	experimental group:rituximab;control group:tacrolimus;	Xinqiao Hospital	NULL	Pending	18	80	Both	experimental group:40;control group:40;	Phase 4	China
8	ChiCTR2000033540	2020-06-01	2020-06-04	Prospective Randomized Trial on Efficacy of RituximabCombined Therapy and Supportive Therapy on Earl ...	Prospective Randomized Trial on Efficacy of RituximabCombined Therapy and Supportive Therapy on Earl ...	Membranous Nephropathy	experimental group:Rituximab600mg iv, and supportive treatment;control group:Supportive treatment ac ...	Peking Union Medical College Hospital, Chinese Academy of Medical Sciences	NULL	Recruiting	18	70	Both	experimental group:19;control group:19;	Phase 4	China
9	ChiCTR2000040799	2020-05-20	2020-12-10	Prospective study of rituximabcombined with low-dose hormone in the treatment of idiopathic membrano ...	Prospective study of rituximabcombined with low-dose hormone in the treatment of idiopathic membrano ...	idiopathic membranous nephropathy	Single arm:Rituximab;	The First Affiliated Hospital, Sun Yat-Sen University	NULL	Recruiting	18		Both	Single arm:50;	Phase 4	China
10	EUCTR2019-001734-34-NL (EUCTR)	07/04/2020	22/08/2019	Efficacy and safety of LNP023 compared with rituximabin subjects with idiopathic membranous nephropa ...	A randomized, open-label, two-arm, parallel group, proof-of-concept clinical trial to investigate th ...	Idiopathic Membranous nephropathy MedDRA version: 21.1;Level: LLT;Classification code 10027170;Term: ...	Product Code: LNP023 INN or Proposed INN: iptacopan Other descriptive name: LNP023 HYDROCHLORIDE SALT ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	52	Phase 2	United States;Czechia;Taiwan;Spain;Russian Federation;United Kingdom;India;France;Argentina;Singapor ...

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