265. 脂肪萎縮症 Lipodystrophy Clinical trials / Disease details
臨床試験数 : 116 / 薬物数 : 170 - (DrugBank : 61) / 標的遺伝子数 : 26 - 標的パスウェイ数 : 97
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01612858 (ClinicalTrials.gov) | June 2011 | 4/6/2012 | Metabolic Abnormalities in HIV-infected Persons | Metabolic Abnormalities in HIV-infected Persons | Lipodystrophy;HIV Infection | Drug: Metformin;Drug: Pioglitazone | Tufts Medical Center | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Completed | 18 Years | 70 Years | All | 20 | Phase 4 | United States |
| 2 | NCT01023620 (ClinicalTrials.gov) | October 2009 | 30/11/2009 | HIV Acquired Lipodystrophy (HAL) Classification, Measurement and Fat Response to Thiazolidinedione (TZD) (Pioglitazone) | Human Immunodeficiency Virus Acquired Lipodystrophy (HAL) Classification, Measurement, & Fat Response to a Thiazolidinedione (TZD) Challenge in Differing Adult Phenotypic Presentations | HIV Infections | Drug: Pioglitazone;Other: Observation | University of Texas Southwestern Medical Center | Takeda Pharmaceuticals North America, Inc. | Completed | 18 Years | N/A | Male | 4 | N/A | United States |
| 3 | NCT00362440 (ClinicalTrials.gov) | August 2006 | 9/8/2006 | Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome | A Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome: A Randomized, Double-blind, Placebo-controlled Clinical Trial | HIV Lipodystrophy | Drug: Leptin;Drug: Pioglitazone or metformin;Drug: Placebo | Beth Israel Deaconess Medical Center | American Diabetes Association | Completed | 18 Years | N/A | All | 9 | Phase 2 | United States |
| 4 | NCT00656851 (ClinicalTrials.gov) | September 2005 | 10/4/2008 | Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome | Myocardial Function, Free Fatty Acid and Glucose Metabolism in HIV Metabolic Syndrome | HIV Infections;Cardiovascular Disease;Insulin Resistance;HIV Lipodystrophy;The Metabolic Syndrome | Drug: Pioglitazone;Behavioral: Exercise Training | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | NULL | Completed | 28 Years | 50 Years | All | 24 | N/A | United States |
| 5 | NCT00639457 (ClinicalTrials.gov) | January 2005 | 18/3/2008 | Exercise and Pioglitazone for HIV-Metabolic Syndromes | Exercise and Pioglitazone for HIV-Metabolic Syndromes | HIV Infections;Type 2 Diabetes;Obesity;HIV;AIDS;Cardiovascular Disease;Lipodystrophy | Drug: Pioglitazone;Behavioral: Exercise training | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | NULL | Completed | 18 Years | 65 Years | All | 44 | N/A | United States |
| 6 | NCT00148850 (ClinicalTrials.gov) | February 2003 | 7/9/2005 | Effect of Pioglitazone on HIV-1 Related Lipoatrophy: a Randomized, Double Blind, Placebo-Controlled Trial in 130 Patients | A Randomized, Phase 3, Double Blind, Multicentre Trial, Evaluating the Effect of Pioglitazone Versus Placebo on Change in Lipoatrophy in HIV- 1 Infected Patients Treated With Stable Antiretroviral Therapy for at Least 6 Months.ANRS 113 LIPIOT Study | HIV-Associated Lipodystrophy Syndrome;HIV Infections | Drug: Pioglitazone | French National Agency for Research on AIDS and Viral Hepatitis | Takeda | Terminated | 18 Years | N/A | Both | 130 | Phase 3 | France |