271. 強直性脊椎炎 Ankylosing spondylitis Clinical trials / Disease details

臨床試験数 : 563 / 薬物数 : 372 - (DrugBank : 72) / 標的遺伝子数 : 41 - 標的パスウェイ数 : 145

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05155098 (ClinicalTrials.gov)	March 1, 2022	30/11/2021	2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness ...	2 Years Prospective Study to Collect Real-life Data On the Retention, Quality of Life, Effectiveness ...	Moderate to Severe Plaque Psoriasis;Psoriatic Arthritis;Ankylosing Spondylitis;Non-radiographic Axia ...	Other: secukinumab	Novartis Pharmaceuticals	NULL	Not yet recruiting	18 Years	80 Years	All	360		NULL
2	NCT05257174 (ClinicalTrials.gov)	March 2022	28/1/2022	The Effects of Jing Si Herbal Tea Liquid Packets on Fatigue in Patients With Inflammatory Arthritis	A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Jing Si Herbal Tea L ...	Arthritis;Rheumatoid Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Fatigue	Dietary Supplement: Jing Si Herbal Tea LIQUID PACKETS;Dietary Supplement: Placebo	Buddhist Tzu Chi General Hospital	NULL	Not yet recruiting	20 Years	99 Years	All	150	N/A	Taiwan
3	NCT05164198 (ClinicalTrials.gov)	January 15, 2022	8/11/2021	Multicenter, Prospective Clinical Trial for Optimizing TNF Inhibitor Dose Adjustment in Ankylosing S ...	Multicenter, Prospective Clinical Trial for Optimizing TNF Inhibitor Dose Adjustment in Ankylosing S ...	Ankylosing Spondylitis;Axial Spondyloarthritis	Biological: Adalimumab and its biosimilars;Biological: Biological: Etanercept and its biosimilars;Bio ...	Hanyang University Seoul Hospital	Linical Korea	Not yet recruiting	18 Years	65 Years	All	448	Phase 4	NULL
4	NCT04924270 (ClinicalTrials.gov)	January 2022	7/6/2021	Safety and Efficacy of Faecal Microbiota Transplantation in Treatment-naïve Patients With Newly Diag ...	Safety and Clinical Efficacy Associated With Faecal Microbiota Transplantation Performed in Treatmen ...	Rheumatoid Arthritis;Reactive Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Gouty Arthritis;P ...	Biological: Faecal microbiota transplantation;Other: Placebo	Torkell Ellingsen	Region of Southern Denmark;University of Southern Denmark	Not yet recruiting	18 Years	70 Years	All	200	Phase 2	NULL
5	NCT05212051 (ClinicalTrials.gov)	December 10, 2021	30/11/2021	Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients Wi ...	A Randomized, Double-blind, Placebo-controlled, Phase II, Multicenter Study to Evaluate the Prelimin ...	Active Ankylosing Spondylitis	Biological: JS005;Biological: Placebo	Shanghai Junshi Bioscience Co., Ltd.	Sponsor GmbH	Recruiting	18 Years	65 Years	All	120	Phase 2	China
6	NCT05094128 (ClinicalTrials.gov)	November 22, 2021	20/10/2021	A Study to Assess Disease Activity in Adult Participants With Ankylosing SpondylitisWho Receive Upad ...	Effectiveness of Upadacitinib in Patients With Ankylosing SpondylitisSuffering From Typical Disease ...	Radiographic Axial Spondylarthritis (r-axSpA)	Drug: Upadacitinib	AbbVie	NULL	Recruiting	18 Years	N/A	All	352		Germany
7	NCT04876781 (ClinicalTrials.gov)	November 1, 2021	20/4/2021	Korean Post-marketing Surveillance for Xeljanz XR	Korean Post-marketing Surveillance for Xeljanz XR (Registered)	Active Moderate to Severe Rheumatoid Arthritis;Active Ankylosing Spondylitis	Drug: Tofacitinib XR	Pfizer	NULL	Not yet recruiting	18 Years	N/A	All	200		NULL
8	NCT04947579 (ClinicalTrials.gov)	August 25, 2021	23/6/2021	A Study of CC-99677 in Participants With Active Ankylosing Spondylitis	A Phase 2 Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Evalu ...	Spondylitis, Ankylosing	Drug: CC -99677;Other: Placebo	Celgene	NULL	Recruiting	18 Years	65 Years	All	256	Phase 2	United States;Canada;Czechia;Germany;Poland;Romania;Russian Federation;Spain;Turkey
9	NCT04795141 (ClinicalTrials.gov)	August 24, 2021	3/3/2021	ABY-035 in the Treatment of Subjects With Ankylosing Spondylitis	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety a ...	Ankylosing Spondylitis	Drug: ABY-035;Drug: Normal saline	Inmagene Biopharmaceuticals	Affibody	Recruiting	18 Years	N/A	All	300	Phase 2	Cayman Islands
10	EUCTR2020-004284-98-GR (EUCTR)	15/07/2021	05/04/2021	Secukinumab open label roll-over extension protocol	An open-label, multi-center protocol for patients who have completed a previous Novartis sponsored S ...	Psoriatic Arthritis, Ankylosing Spondylitis, non-radiographic axial spondyloarthritis, Severe Chroni ...	Trade Name: Cosentyx Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: secukinumab Oth ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	628	Phase 4	United States;Czechia;Greece;Spain;Guatemala;Russian Federation;Colombia;India;Egypt;Mexico;Poland;B ...

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