279. 巨大静脈奇形（頚部口腔咽頭びまん性病変） Huge venous malformation with cervical, oral and pharyngeal diffuse lesion Clinical trials / Disease details

臨床試験数 : 14 / 薬物数 : 24 - (DrugBank : 9) / 標的遺伝子数 : 3 - 標的パスウェイ数 : 105

3 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04861064 (ClinicalTrials.gov)	May 18, 2021	23/4/2021	Weekly Sirolimus Therapy	Weekly Sirolimus Therapy for the Treatment of Venous and Lymphatic Malformations	Venous Malformation;Lymphatic Malformation	Drug: Sirolimus	Medical University of South Carolina	NULL	Recruiting	2 Years	N/A	All	24	Phase 2	United States
2	NCT03767660 (ClinicalTrials.gov)	July 31, 2018	24/11/2018	Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous Malformation	Efficacy of Rapamycin (Sirolimus) in the Treatment of Blue Rubber Bleb Nevus Syndrome, Hereditary or Sporadic Venous Malformation	Blue Rubber Bleb Nevus Syndrome;Venous Malformation	Drug: Rapamycin	Peking Union Medical College Hospital	Air Force General Hospital of the PLA;Chinese Academy of Medical Sciences	Recruiting	N/A	N/A	All	20	Phase 4	China
3	NCT00975819 (ClinicalTrials.gov)	October 2009	10/9/2009	Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies	A Phase 2 Study - Clinical Trial Assessing Efficacy and Safety of the mTOR Inhibitor Sirolimus in the Treatment of Complicated Vascular Anomalies	Kaposiform Hemangioendotheliomas;Tufted Angioma;Capillary Venous Lymphatic Malformation;Venous Lymphatic Malformation;Microcystic Lymphatic Malformation;Mucocutaneous Lymphangiomatosis and Thrombocytopenia;Capillary Lymphatic Arterial Venous Malformations;PTEN Overgrowth Syndrome With Vascular Anomaly;Lymphangiectasia Syndromes	Drug: sirolimus	Children's Hospital Medical Center, Cincinnati	NULL	Active, not recruiting	N/A	31 Years	Both	60	Phase 2	United States