299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details

臨床試験数 : 1,696 / 薬物数 : 1,644 - (DrugBank : 272) / 標的遺伝子数 : 96 - 標的パスウェイ数 : 170

51 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02535130 (ClinicalTrials.gov)	August 2015	24/8/2015	Evaluation of Nebulization and Positive Expiratory Pressure Combination		Cystic Fibrosis;Healthy Subjects	Device: Positive expiratory pressure;Drug: amikacine nebulization	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	NULL	Recruiting	16 Years	55 Years	Both	15	N/A	Belgium
2	NCT02489955 (ClinicalTrials.gov)	February 2015	18/5/2015	Antibiotic Nephrotoxicity in Adult Patients With Cystic Fibrosis	Prospective Randomised Trial of 'Area Under the Curve' (AUC) Dosing Strategy for Intravenous Tobramy ...	Cystic Fibrosis	Drug: Amikacin;Drug: Tobramycin;Drug: Colomycin	The Leeds Teaching Hospitals NHS Trust	NULL	Recruiting	18 Years	N/A	Both		N/A	United Kingdom
3	ChiCTR-IPC-15005915	2015-01-31	2014-07-06	A Randomized, Controlled Study of Combined the therapy of bronchoalveolar lavage and Amikacininjecti ...	A Randomized, Controlled Study of Combined the therapy of bronchoalveolar lavage and Amikacininjecti ...	non-cystic fibrosis bronchiectasis	Experimental group:Routine treatment combining with the therapy of bronchoalveolar lavage and local ...	Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicin ...	NULL	Recruiting	18	80	Both	Experimental group:50;		NULL
4	NCT02084043 (ClinicalTrials.gov)	March 2014	8/3/2014	In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilatio ...	In Vitro Comparison of Continuous and Breath-synchronized Vibrating Mesh Nebulizer During Non Invasi ...	Respiratory Diseases;Lung Diseases;Cystic Fibrosis;COPD;Asthma	Drug: Nebulization of Amikacinduring NIV (RR: 15 cycles/minute);Drug: Nebulization of Amikacinduring ...	University Hospital St Luc, Brussels	Université Catholique de Louvain;University of Applied Sciences of Western Switzerland;School of Ges ...	Completed	N/A	N/A	Both	3	N/A	Belgium;Switzerland
5	NCT02081963 (ClinicalTrials.gov)	March 2014	6/3/2014	Combined Administration of Nebulized Amikacinin Patients With Acute Exacerbation of Non-Cystic Fibro ...	A Randomized, Controlled Study of Combined Administration of Nebulized Amikacinin Patients With Acut ...	Non-Cystic Fibrosis Bronchiectasis	Drug: Amikacin;Drug: Normal saline	Qilu Hospital of Shandong University	NULL	Completed	18 Years	80 Years	All	178	Phase 4	China
6	EUCTR2011-000443-24-NL (EUCTR)	25/04/2013	06/07/2011	Long Term Safety and Tolerability Study of Arikace™ in Cystic Fibrosis Patients with Chronic Infecti ...	Long Term Safety and Tolerability Study of Open-Label Liposomal Amikacinfor Inhalation (Arikace™) in ...	Pseudomonas aeruginosa pulmonary infection / colonisation in patientswith cystic fibrosis MedDRA ver ...	Product Name: Liposomal Amikacin (Arikace™) INN or Proposed INN: AMIKACIN SULFATE	Insmed Incorporated	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	250		United States;Slovakia;Greece;Spain;Ireland;Austria;Italy;United Kingdom;France;Hungary;Canada;Polan ...
7	EUCTR2011-000443-24-DK (EUCTR)	14/12/2012	22/07/2011	Long Term Safety and Tolerability Study of Arikace™ in Cystic Fibrosis Patients with Chronic Infecti ...	Long Term Safety and Tolerability Study of Open-Label Liposomal Amikacinfor Inhalation (Arikace™) in ...	Pseudomonas aeruginosa pulmonary infection / colonisation in patientswith cystic fibrosis MedDRA ver ...	Product Name: Liposomal Amikacin (Arikace™) INN or Proposed INN: AMIKACIN SULFATE	Insmed Incorporated	NULL	Not Recruiting			Female: yes Male: yes	250		United States;Slovakia;Greece;Spain;Ireland;Austria;United Kingdom;Italy;France;Hungary;Canada;Polan ...
8	NCT01316276 (ClinicalTrials.gov)	October 5, 2012	14/3/2011	Extension Study of Liposomal Amikacinfor Inhalation in Cystic Fibrosis (CF) Patients With Chronic Ps ...	Long Term Safety and Tolerability Study of Open-Label Liposomal Amikacinfor Inhalation (ARIKACE™) in ...	Cystic Fibrosis	Drug: Liposomal amikacin for inhalation	Insmed Incorporated	NULL	Completed	6 Years	N/A	All	206	Phase 3	Austria;Belgium;Bulgaria;Canada;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Pola ...
9	EUCTR2011-000441-20-NL (EUCTR)	11/09/2012	06/07/2011	Efficacy, safety and tolerability of Arikace™ compared to TOBI in Cystic Fibrosis patients with chro ...	Randomized, open-label, active-controlled, multicenter study to assess the efficacy, safety and tole ...	Pseudomonas aeruginosa pulmonary infection / colonisation in patients with cystic fibrosis MedDRA ve ...	Product Name: Liposomal Amikacin(Arikace™) INN or Proposed INN: AMIKACIN SULFATE Trade Name: TOBI 300mg ...	Insmed Incorporated	NULL	Not Recruiting			Female: yes Male: yes	300		Italy;France;Hungary;Canada;Belgium;Poland;Denmark;Bulgaria;Netherlands;Germany;United States;Slovak ...
10	NCT02201082 (ClinicalTrials.gov)	September 2012	20/2/2014	Evaluation of the Timing of the Nebulization Related to the Physiotherapy Session		Cystic Fibrosis	Procedure: Airway clearance technique;Drug: Amikacin nebulization	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	NULL	Completed	16 Years	50 Years	Both	15	N/A	Belgium

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