299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details


臨床試験数 : 1,696 薬物数 : 1,644 - (DrugBank : 272) / 標的遺伝子数 : 96 - 標的パスウェイ数 : 170

  
2 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02564354
(ClinicalTrials.gov)
September 201529/9/2015Exploratory Study to Evaluate QR-010 in Subjects With Cystic Fibrosis ?F508 CFTR MutationOpen-Label, Exploratory Study to Evaluate the Effects of QR-010 on Nasal Potential Difference in Subjects With CF With the ?F508 CFTR MutationCystic FibrosisDrug: QR-010ProQR TherapeuticsEuropean CommissionCompleted18 YearsN/AAll18Phase 1United States;Belgium;France
2NCT02532764
(ClinicalTrials.gov)
June 201513/8/2015Dose Escalation Study of QR-010 in Homozygous ?F508 Cystic Fibrosis PatientsPhase 1b, Randomized, Double-blind, Placebo-controlled, Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of QR-010 in Subjects With Homozygous ?F508 Cystic FibrosisCystic FibrosisDrug: QR-010;Drug: PlaceboProQR TherapeuticsEuropean CommissionCompleted18 Years60 YearsAll70Phase 1/Phase 2United States;Belgium;Canada;Czechia;Denmark;France;Germany;Italy;Spain;United Kingdom;Czech Republic;Netherlands