3. 脊髄性筋萎縮症 Spinal muscular atrophy Clinical trials / Disease details

臨床試験数 : 217 / 薬物数 : 149 - (DrugBank : 33) / 標的遺伝子数 : 54 - 標的パスウェイ数 : 80

34 trials found

diseases per page:

Showing 1 to 10 of 34 diseases

Filter by

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-005995-37-PT (EUCTR)	15/10/2021	19/07/2021	Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atro ...	A Phase lllb, open-label, single-arm, single-dose, multicenter study to evaluate the safety, tolerab ...	Spinal Muscular Atrophy MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mus ...	Trade Name: Zolgensma 2 x 1013 vector genomes/mL solution for infusion Product Name: OAV101 Product Cod ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	24	Phase 3	United States;France;Portugal;Taiwan;Canada;Spain;Belgium;Australia;Germany;United Kingdom;Switzerla ...
2	EUCTR2020-005995-37-IT (EUCTR)	28/09/2021	17/08/2021	Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atro ...	A Phase IIIb, open-label, single-arm, single-dose, multicenter study to evaluate the safety, tolerab ...	Spinal Muscular Atrophy MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mus ...	Trade Name: Prednisolone Product Name: Prednisolone Product Code: [-] INN or Proposed INN: PREDNISOLONE ...	NOVARTIS PHARMA AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	30	Phase 3	Portugal;France;United States;Taiwan;Canada;Spain;Belgium;Australia;Germany;United Kingdom;Switzerla ...
3	EUCTR2020-005995-37-BE (EUCTR)	03/09/2021	28/06/2021	Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atro ...	A Phase lllb, open-label, single-arm, single-dose, multicenter study to evaluate the safety, tolerab ...	Spinal Muscular Atrophy MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mus ...	Trade Name: Zolgensma 2 x 1013 vector genomes/mL solution for infusion Product Name: OAV101 Product Cod ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	24	Phase 3	Portugal;France;United States;Taiwan;Canada;Spain;Belgium;Australia;Germany;United Kingdom;Switzerla ...
4	EUCTR2020-005995-37-FR (EUCTR)	25/08/2021	21/06/2021	Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atro ...	A Phase lllb, open-label, single-arm, single-dose, multicenter study to evaluate the safety, tolerab ...	Spinal Muscular Atrophy MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mus ...	Trade Name: Zolgensma Product Name: OAV101 Product Code: AVXS-101 INN or Proposed INN: ONASEMNOGENE ABE ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	30	Phase 3	Portugal;United States;France;Taiwan;Canada;Spain;Belgium;Australia;Germany;United Kingdom;Switzerla ...
5	EUCTR2020-003492-18-DE (EUCTR)	07/06/2021	18/03/2021	A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abep ...	A Phase 4 Study of Nusinersen (BIIB058) Among Patients With Spinal Muscular Atrophy Who Received Ona ...	Muscular Atrophy, Spinal MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mu ...	Trade Name: Spinraza INN or Proposed INN: Nusinersen Other descriptive name: NUSINERSEN SODIUM	Biogen Idec Research Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	United States;Spain;Israel;Germany;Italy
6	EUCTR2020-003492-18-ES (EUCTR)	02/06/2021	01/09/2021	A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abep ...	A Phase 4 Study of Nusinersen (BIIB058) Among Patients With Spinal Muscular Atrophy Who Received Ona ...	Muscular Atrophy, Spinal MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mu ...	Trade Name: Spinraza INN or Proposed INN: Nusinersen Other descriptive name: NUSINERSEN SODIUM	Biogen Idec Research Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	United States;Spain;Israel;Germany;Italy
7	EUCTR2020-003492-18-IT (EUCTR)	26/04/2021	08/06/2021	A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abep ...	A Phase 4 Study of Nusinersen (BIIB058) Among Patients With Spinal Muscular Atrophy Who Received Ona ...	Muscular Atrophy, Spinal;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]	Trade Name: Spinraza Product Name: . Product Code: [.] INN or Proposed INN: Nusinersen Other descriptive ...	BIOGEN IDEC RESEARCH LIMITED	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	United States;Spain;Israel;Germany;Italy
8	NCT04488133 (ClinicalTrials.gov)	January 7, 2021	20/7/2020	A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abep ...	A Phase 4 Study of Nusinersen (BIIB058) Among Patients With Spinal Muscular Atrophy Who Received Ona ...	Muscular Atrophy, Spinal	Drug: Nusinersen	Biogen	NULL	Recruiting	2 Months	36 Months	All	60	Phase 4	United States;Germany;Israel;Italy;Spain
9	EUCTR2019-002611-26-FR (EUCTR)	16/09/2020	10/03/2020	not applicable	A Long-term Follow-up Study of Patients in the Clinical Trials forSpinal Muscular Atrophy Receiving ...	Spinal Muscular Atrophy;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Product Name: AVXS-101 Product Code: AVXS-101 INN or Proposed INN: ONASEMNOGENE ABEPARVOVEC	AveXis, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	308	Phase 3	Korea, Republic of;Italy;Japan;United Kingdom;Australia;Belgium;Spain;Canada;Taiwan;France;United St ...
10	EUCTR2019-002611-26-IT (EUCTR)	27/04/2020	03/08/2021	not applicable	A Long-term Follow-up Study of Patients in the Clinical Trials for Spinal Muscular Atrophy Receiving ...	Spinal Muscular Atrophy MedDRA version: 20.1;Level: PT;Classification code 10041582;Term: Spinal mus ...	Product Name: AVXS-101 Product Code: [AVXS-101] INN or Proposed INN: ONASEMNOGENE ABEPARVOVEC	AVEXIS, INC.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	308	Phase 3	France;United States;Taiwan;Canada;Spain;Belgium;Australia;United Kingdom;Japan;Italy;Korea, Republi ...

First Previous1 2 3 4Next Last