34. 神経線維腫症 Neurofibromatosis Clinical trials / Disease details

臨床試験数 : 137 / 薬物数 : 213 - (DrugBank : 76) / 標的遺伝子数 : 87 - 標的パスウェイ数 : 200

3 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02839720 (ClinicalTrials.gov)	April 11, 2017	20/7/2016	Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma	Pilot Study of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) for Adults With Neurofibr ...	Cutaneous Neurofibroma;Neurofibromatosis Type 1;Optic Nerve Glioma	Other: Laboratory Biomarker Analysis;Drug: Selumetinib Sulfate	National Cancer Institute (NCI)	NULL	Active, not recruiting	18 Years	N/A	All	24	Phase 2	United States
2	NCT02415153 (ClinicalTrials.gov)	July 14, 2015	13/4/2015	Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous ...	A Phase I Trial of Pomalidomide for Children With Recurrent, Progressive, or Refractory CNS Tumors	Neurofibromatosis Type 1;Recurrent Childhood Brain Stem Glioma;Recurrent Childhood Visual Pathway Gl ...	Other: Laboratory Biomarker Analysis;Other: Pharmacological Study;Drug: Pomalidomide	National Cancer Institute (NCI)	NULL	Active, not recruiting	3 Years	20 Years	All	29	Phase 1	United States
3	NCT01089101 (ClinicalTrials.gov)	April 19, 2010	17/3/2010	Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma	A Phase 1 and Phase II and Re-Treatment Study of AZD6244 for Recurrent or Refractory Pediatric Low G ...	Low Grade Glioma;Recurrent Childhood Pilocytic Astrocytoma;Recurrent Neurofibromatosis Type 1;Recurr ...	Other: Laboratory Biomarker Analysis;Other: Pharmacological Study;Drug: Selumetinib	National Cancer Institute (NCI)	NULL	Active, not recruiting	3 Years	21 Years	All	220	Phase 1/Phase 2	United States

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