40. 高安動脈炎 Takayasu arteritis Clinical trials / Disease details
臨床試験数 : 25 / 薬物数 : 50 - (DrugBank : 21) / 標的遺伝子数 : 25 - 標的パスウェイ数 : 114
Showing 1 to 10 of 10 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT04564001 (ClinicalTrials.gov) | September 2020 | 21/9/2020 | Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocilizumab in Refractory or Relapsing Takayasu Arteritis Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocil ... | Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocilizumab in Refractory or Relapsing Takayasu Arteritis Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocil ... | Takayasu Arteritis | Drug: Infliximab;Drug: Tocilizumab | Assistance Publique - Hôpitaux de Paris | NULL | Not yet recruiting | 18 Years | N/A | All | 50 | Phase 2 | NULL |
2 | NCT04300686 (ClinicalTrials.gov) | March 1, 2020 | 5/3/2020 | A Pilot Study in Severe Patients With Takayasu Arteritis. | A Pilot Study in the Treatment of Severe Patients With Takayasu Arteritis With Tocilizumab and Adalimumab, Based on ECTA Cohort A Pilot Study in the Treatment of Severe Patients With Takayasu Arteritis With Tocilizumaband Adalim ... | Takayasu Arteritis;Tocilizumab;Adalimumab;Treatment | Biological: Tocilizumab;Biological: Adalimumab | Shanghai Zhongshan Hospital | NULL | Recruiting | 14 Years | 100 Years | All | 40 | Phase 4 | China |
3 | EUCTR2018-003753-13-FR (EUCTR) | 19/03/2019 | 13/12/2018 | INTOReTAK : INfliximab and TOcilizumab in Refractory/relapsing TAKayasu arteritis | Multicentre, randomized, prospective trial comparing the efficacy and safety of Infliximab to tocilizumab in refractory or relapsing Takayasu arteritis Multicentre, randomized, prospective trial comparing the efficacy and safety of Infliximab to tocili ... | Patients with refractory or relapsing Takayasu Arteritis desease;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02] Patients with refractory or relapsing Takayasu Arteritis desease;Therapeutic area: Analytical, Diagn ... | Trade Name: RoActemra 20mg/ml Product Name: Tocilizumab INN or Proposed INN: Tocilizumab Other descriptive name: TOCILIZUMAB Product Name: Infliximab INN or Proposed INN: INFLIXIMAB Trade Name: RoActemra20mg/ml Product Name: Tocilizumab INN or Proposed INN: Tocilizumab Other descripti ... | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 50 | Phase 3 | France | ||
4 | JPRN-UMIN000025940 | 2017/02/07 | 07/02/2017 | Clinical Research on the Safety of anti-interleukin-6 antibody (Tocilizumab) treatment for the refractory patients with Takayasu Arteritis Clinical Research on the Safety of anti-interleukin-6 antibody (Tocilizumab) treatment for the refra ... | Clinical Research on the Safety of anti-interleukin-6 antibody (Tocilizumab) treatment for the refractory patients with Takayasu Arteritis - TOCIlizumab treatment for TAKayasu arteritis (TOCI-TAK) Clinical Research on the Safety of anti-interleukin-6 antibody (Tocilizumab) treatment for the refra ... | Takayasu arteritis | Intravenous administration of tocilizumab (8mg/kg/month) for up to 12 months | Osaka University | National Cerebral and Cardiovascular Center | Complete: follow-up continuing | 16years-old | 60years-old | Male and Female | 2 | Not selected | Japan |
5 | NCT03893136 (ClinicalTrials.gov) | November 1, 2016 | 12/3/2019 | The Registry Study of Takayasu Arteritis in East China | The Cohort Study of East Chinese Takayasu's Arteritis (ECTA-cohort Study) | Takayasu Arteritis;Mechanisms, Defense;Pregnancy Related;Treatment Refusal;Outcome | Biological: Tocilizumab;Drug: Leflunomide | Shanghai Zhongshan Hospital | NULL | Recruiting | 18 Years | 65 Years | All | 1000 | China | |
6 | JPRN-JapicCTI-142616 | 02/10/2014 | 23/07/2014 | Phase III Study of MRA-SC in Patients with Takayasu Arteritis | A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase III Study of MRA-SC in Patients with Takayasu Arteritis A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase III Study of MRA-SC in Patients ... | Takayasu Arteritis | Intervention name : tocilizumab (MRA-SC) INN of the intervention : tocilizumab Dosage And administration of the intervention : 162mg/W, SC Control intervention name : Placebo INN of the control intervention : - Dosage And administration of the control intervention : Placebo/W, SC Intervention name : tocilizumab(MRA-SC) INN of the intervention : tocilizumab Dosage And administratio ... | Chugai Pharmaceutical Co., Ltd. | NULL | complete | 12 | BOTH | 34 | Phase 3 | Japan | |
7 | JPRN-UMIN000025943 | 2014/08/07 | 07/02/2017 | Long-term Safety of treatment with tocilizumab in the refractory patients with Takayasu Arteritis | Long-term Safety of treatment with tocilizumab in the refractory patients with Takayasu Arteritis - Long-term ACTemra Investigation for remissION introduction in TAKayasu Arteritits (LACTION-TAK) Long-term Safety of treatment with tocilizumabin the refractory patients with Takayasu Arteritis - L ... | Takayasu arteritis | Intravenous administration of tocilizumab (8mg/kg/month) will be performed until December 31st, 2017. | Osaka Unversity | National Cerebral and Cardiovascular Center | Complete: follow-up continuing | 16years-old | 60years-old | Male and Female | 9 | Not selected | Japan |
8 | NCT02101333 (ClinicalTrials.gov) | June 10, 2014 | 17/2/2014 | Efficacy and Tolerance of Tocilizumab In Takayasu Arteritis | Efficacy and Tolerance of First-line Treatment With Tocilizumab in Active Takayasu Arteritis French Prospective Multicenter Study Efficacy and Tolerance of First-line Treatment With Tocilizumabin Active Takayasu Arteritis French P ... | TAKAYASU ARTERITIS | Drug: Tocilizumab | Assistance Publique - Hôpitaux de Paris | Chugai Pharmaceutical | Completed | 18 Years | 77 Years | All | 18 | Phase 3 | France |
9 | JPRN-UMIN000008812 | 2012/10/01 | 01/10/2012 | Efficacy and safety of tocilizumab mono-therapy in patients with large vessel vasculitis (LVV; giant cell arteritis or Takayasu arteritis) and polymyalgia rheumatica (PMR) Efficacy and safety of tocilizumabmono-therapy in patients with large vessel vasculitis (LVV; giant ... | Rheumatoid arthritis | tocilizumab monotherapy | Department of Rheumatology & Clinical ImmunologySaitama Medical Center, Saitama Medical Universitity Department of Rheumatology & Clinical ImmunologySaitama Medical Center, Saitama Medical Universitity ... | NULL | Complete: follow-up complete | 16years-old | 80years-old | Male and Female | 40 | Not selected | Japan | |
10 | JPRN-UMIN000007845 | 2012/05/01 | 01/05/2012 | Efficacy and Safety of treatment with tocilizumab in refractory patients with Takayasu Arteritis | Efficacy and Safety of treatment with tocilizumab in refractory patients with Takayasu Arteritis - ACTemra Investigation for remissiON introduction in Takayasu Arteritits (ACTION-TA) Efficacy and Safety of treatment with tocilizumabin refractory patients with Takayasu Arteritis - AC ... | Takayasu arteritis | Intravenous administration of tocilizumab (8mg/kg/month) for 24 months | Department of Cardiovascular Medicine Graduate School of Medicine Osaka University | NULL | Complete: follow-up continuing | 16years-old | 60years-old | Male and Female | 15 | Not selected | Japan |