46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details
臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224
Showing 1 to 10 of 1,238 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05166304 (ClinicalTrials.gov) | April 2022 | 8/12/2021 | Rebamipide in Patients With Active Rheumatoid Arthritis | Rebamipide as an Adjunct to Methotrexate in Patients With Active Rheumatoid Arthritis | Rheumatoid Arthritis | Drug: Rebamipide;Drug: Placebo | October 6 University | NULL | Not yet recruiting | 18 Years | 60 Years | All | 100 | Phase 1/Phase 2 | NULL |
2 | NCT05264025 (ClinicalTrials.gov) | April 2022 | 10/1/2022 | Fexofenadine in Patients With Active Rheumatoid Arthritis | Fexofenadine as Adjunct to Standard Rheumatoid Therapy in Patients With Active Rheumatoid | Rheumatoid Arthritis | Drug: Fexofenadine;Drug: Placebo | October 6 University | NULL | Not yet recruiting | 18 Years | 60 Years | All | 80 | Phase 1/Phase 2 | NULL |
3 | NCT05238896 (ClinicalTrials.gov) | March 1, 2022 | 4/1/2022 | BARIcitinib Cognitive Emotional and Neural signaTuRE | BARIcitinib Cognitive Emotional and Neural signaTuRE (BARICENTRE) | Rheumatoid Arthritis | Drug: Baricitinib Oral Tablet [Olumiant];Drug: Placebo | Assistance Publique - Hôpitaux de Paris | NULL | Not yet recruiting | 18 Years | 75 Years | All | 80 | Phase 4 | France |
4 | EUCTR2021-004131-84-NL (EUCTR) | 14/02/2022 | 08/09/2021 | Comparing the effectiveness of tofacitinib extended release (XR) chronotherapy, morning versus evening dosing, in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients from a patient’s, clinical as well as a translational point of view. Comparing the effectiveness of tofacitinib extended release (XR) chronotherapy, morning versus eveni ... | Chronotherapy in Inflammatory Arthritis (ChronIA trial): a crossover randomized controlled trial comparing the effectiveness of morning and evening dosing of tofacitinib extended-release - ChronIA trial Chronotherapy in Inflammatory Arthritis (ChronIA trial): a crossover randomized controlled trial com ... | Rheumatoid arthritis or psoriatic arthritis according to respectively 2010 criteria or CASPAR criteria MedDRA version: 23.1;Level: PT;Classification code 10039073;Term: Rheumatoid arthritis;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders MedDRA version: 21.0;Level: LLT;Classification code 10037160;Term: Psoriatic arthritis;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] Rheumatoid arthritis or psoriatic arthritis according to respectively 2010 criteria or CASPAR criter ... | Trade Name: Xeljanz XR Product Name: Tofacitinib XR Product Code: EMEA/H/C/004214 | Erasmus Medical Center | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 84 | Phase 4 | Netherlands | ||
5 | NCT04688398 (ClinicalTrials.gov) | January 10, 2022 | 14/12/2020 | Study of the Impact of Fatty Acids From Seal Oil on the Relief of Symptoms Associated With Rheumatoid Arthritis Study of the Impact of Fatty Acids From Seal Oil on the Relief of Symptoms Associated With Rheumatoi ... | Study of the Impact of Fatty Acids From Seal Oil on the Relief of Symptoms Associated With Rheumatoid Arthritis Study of the Impact of Fatty Acids From Seal Oil on the Relief of Symptoms Associated With Rheumatoi ... | Polyarthritis | Dietary Supplement: Seal oil;Dietary Supplement: Control | Laval University | Ministry of Agriculture, Fisheries and Food, Quebec;Groupe De Recherche En Rhumatologie Et Maladies Osseuses Inc. Ministry of Agriculture, Fisheries and Food, Quebec;Groupe De Recherche En Rhumatologie Et Maladies ... | Not yet recruiting | 18 Years | N/A | All | 130 | N/A | NULL |
6 | NCT04924270 (ClinicalTrials.gov) | January 2022 | 7/6/2021 | Safety and Efficacy of Faecal Microbiota Transplantation in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases Safety and Efficacy of Faecal Microbiota Transplantation in Treatment-naïve Patients With Newly Diag ... | Safety and Clinical Efficacy Associated With Faecal Microbiota Transplantation Performed in Treatment-naïve Patients With Newly Diagnosed Rheumatoid Arthritis, Reactive Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Gouty Arthritis, Psoriasis, Hidradenitis Suppurativa, Pulmonary Sarcoidosis, Crohn's Disease, and Ulcerative Colitis: a 52-week, Double-blind, Randomised, Placebo-controlled, Exploratory Trial Safety and Clinical Efficacy Associated With Faecal Microbiota Transplantation Performed in Treatmen ... | Rheumatoid Arthritis;Reactive Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Gouty Arthritis;Psoriasis;Hidradenitis Suppurativa;Pulmonary Sarcoidosis;Crohn Disease;Ulcerative Colitis Rheumatoid Arthritis;Reactive Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Gouty Arthritis;P ... | Biological: Faecal microbiota transplantation;Other: Placebo | Torkell Ellingsen | Region of Southern Denmark;University of Southern Denmark | Not yet recruiting | 18 Years | 70 Years | All | 200 | Phase 2 | NULL |
7 | NCT05124782 (ClinicalTrials.gov) | November 30, 2021 | 22/10/2021 | Virtual Management of Rheumatoid Arthritis | Evaluation of Rheumatoid Arthritis at the Time of Telemedicine | Rheumatoid Arthritis | Other: Rheumatoid Arthritis Impact of Disease questionnaire | Assistance Publique - Hôpitaux de Paris | NULL | Recruiting | N/A | N/A | All | 100 | France | |
8 | NCT05053165 (ClinicalTrials.gov) | November 12, 2021 | 16/9/2021 | A Study to Assess the Safety and Tolerability of LB-P6 and LB-P8 in Healthy Participants | A Phase 1, Randomised, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of LB-P6 or LB-P8 in Healthy Participants A Phase 1, Randomised, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Ph ... | Rheumatoid Arthritis;Non-Alcoholic Steatohepatitis | Drug: LB-P6;Drug: LB-P8;Drug: Placebo | LISCure Biosciences | Novotech (Australia) Pty Limited | Recruiting | 18 Years | 65 Years | All | 30 | Phase 1 | Australia |
9 | NCT04985812 (ClinicalTrials.gov) | October 18, 2021 | 6/7/2021 | A Study of JNJ-67484703 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy A Study of JNJ-67484703 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therap ... | A Multicenter, Double-blind, Placebo-controlled, Randomized, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of JNJ-67484703 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy A Multicenter, Double-blind, Placebo-controlled, Randomized, Multiple Dose Study to Assess the Safet ... | Rheumatoid Arthritis | Drug: JNJ-67484703;Drug: Placebo | Janssen Research & Development, LLC | NULL | Recruiting | 18 Years | 65 Years | All | 42 | Phase 1 | United States;Georgia;Hungary;Moldova, Republic of;Spain;Ukraine |
10 | NCT05251870 (ClinicalTrials.gov) | August 17, 2021 | 21/12/2021 | Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis | Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis: the TOLERANT Trial | Rheumatoid Arthritis | Drug: autologous mature tolerogenic monocyte-derived Dendritic Cells loaded with the B29 peptide of HSP70 Drug: autologous mature tolerogenic monocyte-derived Dendritic Cells loaded with the B29 peptide of ... | UMC Utrecht | Radboud University Medical Center;Utrecht University;Trajectum Pharma B.V.;Dutch Arthritis Association;ZonMw: The Netherlands Organisation for Health Research and Development;Health Holland Radboud University Medical Center;Utrecht University;Trajectum Pharma B.V.;Dutch Arthritis Associati ... | Recruiting | 18 Years | N/A | All | 18 | Phase 1/Phase 2 | Netherlands |