46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

13 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02236481 (ClinicalTrials.gov)	July 2013	8/9/2014	Clinical Study to Evaluate the Efficacy of Anakinrain Patients With Rheumatoid Arthritis and Diabete ...	No-profit Study to Ensure Normal Clinical Practice, to Evaluate the Efficacy of Anakinrain Reducing ...	Diabetes Mellitus, Type 2;Arthritis, Rheumatoid	Drug: Anakinra;Drug: TNF alpha inhibitors	Prof. Roberto Giacomelli	NULL	Terminated	18 Years	N/A	All	41	Phase 4	Italy
2	EUCTR2012-005370-62-IT (EUCTR)	18/02/2013	11/01/2013	clinical study to evaluate the efficacy of anakinrain reducing the glycated haemoglobin in patients ...	No-profit” clinical study for the improvement of clinical practice, to evaluate the efficacy of anak ...	rheumatoid arthritis and type 2 diabetes mellitus as comorbidity. MedDRA version: 14.1;Level: LLT;Cl ...	Trade Name: KINERET *SC 7SIR 100MG 0,67ML INN or Proposed INN: ANAKINRA	OSPEDALE CIVILE SAN SALVATORE, ASL 04, L'AQUILA	NULL	Not Recruiting			Female: yes Male: yes	200	Phase 4	Italy
3	NCT02915094 (ClinicalTrials.gov)	October 2012	23/9/2016	Kineret in the Treatment of Rheumatoid Arthritis	Kineret in the Treatment of Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: Anakinra	Swedish Orphan Biovitrum	NULL	Completed	18 Years	N/A	All	30	N/A	Germany
4	NCT01566201 (ClinicalTrials.gov)	March 2011	27/3/2012	Effects of Interleukin-1 Inhibition on Vascular and Left Ventricular Function in Rheumatoid Arthriti ...	The Effect of Inhibition of Interleukin-1 Activity on Vascular and Left Ventricular Function in Pati ...	Rheumatoid Arthritis;Coronary Artery Disease;Inflammation	Drug: anakinra;Drug: placebo	University of Athens	NULL	Completed	18 Years	N/A	Both	80	N/A	Greece
5	ChiCTR-TRC-09000383	2008-01-01	2009-04-23	Efficacy and safety of recombinant human IL-1 receptor antagonist in Chinese patients with rheumatoi ...	Efficacy and safety of recombinant human IL-1 receptor antagonist in Chinese patients with rheumatoi ...	rheumatoid arthritis;M05.901	placebo:daily subcutaneous injections of placebo, with concurrent MTXtherapy ;anakinra:daily subcuta ...	Xi-jing Hospital, the 4th Military Medical University, Shanghai Changzheng Hospital	NULL	Completed	18	65	Both	placebo:10;anakinra:30;	3 (Phase 3 study)	China
6	NCT00111410 (ClinicalTrials.gov)	August 2005	20/5/2005	Evaluating the Effect of Anakinra(r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheuma ...	A Multicenter, Double-Blind, Randomized, Placebo Controlled Study to Estimate the Effect of Anakinra ...	Rheumatoid Arthritis	Drug: Anakinra (r-metHuIL-1ra)	Amgen	NULL	Completed	18 Years	74 Years	Both		Phase 4	NULL
7	NCT00117091 (ClinicalTrials.gov)	September 2004	30/6/2005	Anakinra(Kineret®) in Combination With Disease Modifying Anti-Rheumatic Drugs (DMARDS) in Subjects W ...	An Open-Label Multicentre Study of Anakinra(Kineret®) in Combination With DMARDS in Subjects With Ac ...	Rheumatoid Arthritis	Drug: Anakinra (Kineret®)	Amgen	NULL	Completed	18 Years	N/A	Both		Phase 3	NULL
8	NCT00213538 (ClinicalTrials.gov)	June 2003	13/9/2005	Gene Expression Profiling in PBMCs as a Tool for Prediction of AnakinraResponsiveness in Rheumatoid ...	Gene Expression Profiling in PBMCs as a Tool for Prediction of AnakinraResponsiveness in Rheumatoid ...	Rheumatoid Arthritis	Drug: Response to anakinra associated with methotrexate	University Hospital, Rouen	NULL	Completed	18 Years	N/A	All	341	N/A	France
9	NCT00121043 (ClinicalTrials.gov)	October 2002	30/6/2005	Evaluating Kineret® (Anakinra) in Rheumatoid Arthritis (RA) Subjects Using aSelf-Reported Questionna ...	An Open Label, Randomized, Crossover Study to Assess Acceptability and Functionality of SimpleJectTM ...	Rheumatoid Arthritis	Device: SimpleJectTM;Drug: Kineret® (Anakinra)	Amgen	NULL	Completed	18 Years	N/A	Both		Phase 4	NULL
10	NCT00537667 (ClinicalTrials.gov)	August 2001	27/9/2007	The SPECTRA Study	A Single Centre, Open-Label, Randomised, Study to Evaluate the Effect of Anakinra(r-metHuIL-1ra) Alo ...	Rheumatoid Arthritis	Drug: anakinra;Drug: anakinra and PEG sTNF-R1	Amgen	NULL	Terminated	18 Years	N/A	Both	22	Phase 2	NULL

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