46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

350 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04585711 (ClinicalTrials.gov)	July 2023	7/10/2020	Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis	Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis	Juvenile Idiopathic Arthritis;Rheumatoid Arthritis;Obesity	Drug: Etanercept Optimal dosing	Duke University	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Not yet recruiting	2 Years	65 Years	All	30	Phase 1	United States
2	EUCTR2018-004558-30-DK (EUCTR)	18/12/2020	05/10/2020	A 3-arm, randomized, open-label, parallel active controlled, multicenter international study to comp ...	A 3-arm, randomized, open-label, parallel active controlled, multicenter international study to comp ...	rheumatoid arthritis MedDRA version: 23.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Trade Name: Olumiant Product Name: Olumiant INN or Proposed INN: BARICITINIB Trade Name: Enbrel Product ...	Fundación Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	186	Phase 4	Portugal;Spain;Denmark
3	JPRN-jRCTs071200054	18/11/2020	18/11/2020	Effectiveness of EtanerceptBiosimilar Initiating for Etanercept-Naive Patients, using Ultrasound, Cl ...	Effectiveness of EtanerceptBiosimilar Initiating for Etanercept-Naive Patients, using Ultrasound, Cl ...	Rheumatoid arthritis	Rheumatoid arthritis patients with moderate or high disease activity will be introduce for etanercep ...	Kawakami Atsushi	NULL	Recruiting	>= 20age old	Not applicable	Both	40	Phase 4	Japan
4	NCT04428424 (ClinicalTrials.gov)	July 5, 2020	10/6/2020	Study To Evaluate The Response To Enbrel And The Impact Of Rheumatoid Factor(RF) And Anti-Cyclic Cit ...	The Impact of RF, and Anti-CCP on RA Patients in Response to Etanercept	Arthritis, Rheumatoid	Drug: Enbrel	Pfizer	NULL	Completed	18 Years	N/A	All	1		Iraq
5	JPRN-jRCTs071190046	29/06/2020	20/02/2020	Efficacy of EtanerceptBiosimilar Switching from EtanerceptReference Product, using Ultrasound and Cl ...	Efficacy of EtanerceptBiosimilar Switching from EtanerceptReference Product, using Ultrasound and Cl ...	Rheumatoid arthritis	Rheumatoid arthritis patients who have been treated with enbrel (Subcutaneous injection of 25 mg onc ...	Kawakami Atsushi	NULL	Recruiting	>= 20age old	Not applicable	Both	62	Phase 4	Japan
6	NCT04449224 (ClinicalTrials.gov)	April 27, 2020	7/6/2020	Comparative Effectiveness of Targeted Therapy in RA Patients	Comparative Effectiveness of Biologic Disease-modifying Antirheumatic Drugs and Small Molecular Inhi ...	Rheumatoid Arthritis	Drug: Adalimuab, Etanercept, Tocilizumab, or Abatacept;Drug: Tofacitinib or Baricitinib	Hanyang University	Ministry of Health, Republic of Korea	Recruiting	19 Years	N/A	All	506		Korea, Republic of
7	NCT04115423 (ClinicalTrials.gov)	April 1, 2020	2/10/2019	A Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Rece ...	A Retrospective Cohort Study to Examine the Risk of Serious Infections in Rheumatoid Arthritis Patie ...	Infection;Rheumatoid Arthritis	Drug: Tocilizumab;Drug: Tumor Necrosis Factor Inhibitor (etanercept, infliximab, adalimumab, and gol ...	Sungkyunkwan University	Ministry of Food and Drug Safety, Korea	Active, not recruiting	18 Years	N/A	All	9508		Korea, Republic of
8	EUCTR2019-003700-12-FR (EUCTR)	13/03/2020	04/06/2020	Association between metabolits of methotrexate and clinical response in rheumatoid arthritis patient ...	Association between methotrexate erythrocyte polyglutamate concentration and biological drug concent ...	rheumatoid arthritis MedDRA version: 21.0;Level: LLT;Classification code 10042952;Term: Systemic rhe ...	Product Name: Methotrexate Product Code: MTX Other descriptive name: METHOTREXATE DISODIUM Product Code: ...	CHU Saint-Etienne	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	France
9	NCT03976245 (ClinicalTrials.gov)	March 2020	3/6/2019	Advanced Therapeutics in Rheumatoid Arthritis (RA)	Advanced Therapeutics in Rheumatoid Arthritis (RA)	Rheumatoid Arthritis	Drug: Etanercept;Drug: tofacitinib	Lawson Health Research Institute	Academic Medical Organization of Southwestern Ontario	Recruiting	18 Years	N/A	All	144	Phase 4	Canada
10	EUCTR2018-003351-37-FR (EUCTR)	19/02/2020	28/05/2019	A Phase 3b/4 Study in Rheumatoid Arthritis	A Randomized, Active Controlled, Parallel Group, Phase 3b/4 Study of Baricitinib in Patients with Rh ...	Rheumatoid Arthritis MedDRA version: 20.0;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Trade Name: Olumiant Product Name: Olumiant Product Code: LY3009104 INN or Proposed INN: BARICITINIB Tra ...	Eli Lilly and Company	NULL	Not Recruiting			Female: yes Male: yes	2600	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Slovakia;Greece;Spain;Lithuania;Turkey;Austria;Russian Federation;Israel;Italy;Switzer ...

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