46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

104 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04115423 (ClinicalTrials.gov)	April 1, 2020	2/10/2019	A Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Rece ...	A Retrospective Cohort Study to Examine the Risk of Serious Infections in Rheumatoid Arthritis Patie ...	Infection;Rheumatoid Arthritis	Drug: Tocilizumab;Drug: Tumor Necrosis Factor Inhibitor (etanercept, infliximab, adalimumab, and gol ...	Sungkyunkwan University	Ministry of Food and Drug Safety, Korea	Active, not recruiting	18 Years	N/A	All	9508		Korea, Republic of
2	EUCTR2019-003700-12-FR (EUCTR)	13/03/2020	04/06/2020	Association between metabolits of methotrexate and clinical response in rheumatoid arthritis patient ...	Association between methotrexate erythrocyte polyglutamate concentration and biological drug concent ...	rheumatoid arthritis MedDRA version: 21.0;Level: LLT;Classification code 10042952;Term: Systemic rhe ...	Product Name: Methotrexate Product Code: MTX Other descriptive name: METHOTREXATE DISODIUM Product Code: ...	CHU Saint-Etienne	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	France
3	EUCTR2019-004101-27-NL (EUCTR)	15/01/2020	12/12/2019	Research into injecting golimumab less frequently by using increased doses	INDIGO: Comparing pharmacokinetic parameters of golimumab50 mg and golimumab100 mg with a prolonged ...	rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis MedDRA version: 21.0;Level: PT;Cl ...	Trade Name: Simponi INN or Proposed INN: GOLIMUMAB	Sint Maartenskliniek	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	35	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Netherlands
4	NCT04188249 (ClinicalTrials.gov)	July 1, 2019	27/6/2019	Effectiveness and Adherence of Golimumab in Rheumatoid Arthritis	A Prospective Multicenter Registry of Golimumab in Chinese Patients With Rheumatoid Arthritis	Arthritis, Rheumatoid	Drug: Golimumab	Peking Union Medical College Hospital	NULL	Recruiting	18 Years	80 Years	All	200		China
5	NCT03729349 (ClinicalTrials.gov)	January 15, 2019	1/11/2018	Golimumab for Adherence in Rheumatoid Arthritis	Golimumab for Adherence in Rheumatoid Arthritis	Arthritis, Rheumatoid	Biological: Golimumab	Janssen Inc.	NULL	Recruiting	18 Years	85 Years	All	300		Canada
6	NCT03100253 (ClinicalTrials.gov)	March 1, 2018	17/3/2017	Rheumatoid Arthritis Treatment After First Anti-TNF INvestiGation	Open-label, Randomized Controlled Trial Comparing Tocilizumab to Anti-TNF Treatment and Discovery of ...	Rheumatoid Arthritis	Drug: Tocilizumab;Drug: Etanercept;Drug: Infliximab;Drug: Adalimumab;Drug: Golimumab;Drug: Certolizu ...	Mario Negri Institute for Pharmacological Research	NULL	Recruiting	18 Years	N/A	All	208	Phase 4	Italy
7	EUCTR2016-003129-40-IT (EUCTR)	05/01/2017	10/09/2021	Remission after suspension of TNF alpha therapies in RA	PHASE 4, MULTICENTER RANDOMISED STUDY, AIMED AT EVALUATING THE MAINTENANCE OF REMISSION AFTER 6, 12, ...	RHEUMATOID ARTHRITIS (RA) PATIENTS MedDRA version: 23.1;Level: LLT;Classification code 10003268;Term ...	Trade Name: HUMIRA - 40 MG SOLUZIONE INIETTABILE USO SOTTOCUTANEO 2 SIRINGHE PRERIEMPITE 0.8 ML + 2 ...	AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	Italy
8	NCT03016260 (ClinicalTrials.gov)	December 2016	4/1/2017	RABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFa BIolog ...	Proof-of-Performance Study of RABIOPRED Assay as an In Vitro Diagnostic Test to Identify Patients Wi ...	RheumatoId Arthritis	Biological: Infliximab;Biological: Adalimumab;Biological: Etanercept;Biological: Golimumab;Biologica ...	TcLand Expression S.A.	European Commission	Terminated	18 Years	N/A	All	250		Czechia;France;Israel;Netherlands;Turkey;Czech Republic
9	EUCTR2015-004858-17-NL (EUCTR)	05/10/2016	28/09/2016	REMission INDuction in very early Rheumatoid Arthritis	REMission INDuction in very early Rheumatoid Arthritis - REMINDRA	Very early Rheumatoid arthritis MedDRA version: 19.0;Level: PT;Classification code 10039073;Term: Rh ...	Trade Name: Methotrexate Product Name: Methotrexate Product Code: MTX INN or Proposed INN: Methotrexate ...	University Medical Center Utrecht (UMCU)	NULL	Not Recruiting			Female: yes Male: yes	267	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Netherlands
10	NCT02728934 (ClinicalTrials.gov)	February 25, 2016	31/3/2016	Comparative and Pragmatic Study of GolimumabIntravenous (IV) (Simponi Aria) Versus Infliximab (Remic ...	Comparative and Pragmatic Study of Simponi Aria Versus Remicade in Rheumatoid Arthritis	Arthritis, Rheumatoid	Biological: Golimumab Intravenous (IV);Biological: Infliximab;Biological: Biosimilar Infliximab	Janssen Scientific Affairs, LLC	NULL	Completed	18 Years	N/A	All	1279		United States

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