46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

56 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR2100041909	2021-01-01	2021-01-09	Clinical study on Yupingfengguizhi solution assisted hormone Withdrawal and reduction in rheumatoid ...	Clinical study on Yupingfengguizhi solution assisted hormone Withdrawal and reduction in rheumatoid ...	Rheumatoid arthritis	Treatment group:Yupingfengguizhi solution, Prednisone AcetateTablets, Methotrexate, Leflunomide;contr ...	Yunnan Traditional Chinese Medicine Hospital	NULL	Recruiting	18	65	Both	Treatment group:62;control group:31;		China
2	ChiCTR2100041819	2021-01-01	2021-01-06	Clinical study of Hanbi ointment in the treatment of rheumatoid arthritis	Clinical study of Hanbi ointment in the treatment of rheumatoid arthritis	Rheumatoid arthritis	Treatment group:Hanbi ointment + Methotrexate+ LeflunomideTablets + Folic AcidTablets ;control group ...	The First Affiliated Hospital of Yunnan University of traditional Chinese Medicine	NULL	Recruiting			Both	Treatment group:36;control group:36;		China
3	ChiCTR2100041894	2021-01-01	2021-01-09	Observation on the clinical effect of external application of Yi medicine SISE ointment in the treat ...	Observation on the clinical effect of external application of Yi medicine SISE ointment in the treat ...	Rheumatoid arthritis	therapy group:Yiyisise ointment, Methotrexate, Leflunomidetablets and Folic acidtablets ;Control gro ...	Yunnan Hospital of Traditional Chinese Medicine	NULL	Recruiting			Both	therapy group:36;Control group:36;		China
4	ChiCTR2100041777	2021-01-01	2021-01-05	Clinical study on Juanbi granule in adjuvant hormone withdrawal of rheumatoid arthritis	Clinical study on Juanbi granule in adjuvant hormone withdrawal of rheumatoid arthritis	rheumatoid arthritis	Treatment group:Juanbi granule, Prednisone AcetateTablets, Methotrexateand Leflunomide;control group: ...	Yunnan Hospital of Traditional Chinese Medicine /The First Affiliated Hospital of Yunnan University ...	NULL	Recruiting	18	65	Both	Treatment group:62;control group:31;		China
5	ChiCTR2100041821	2021-01-01	2021-01-06	Observation on the clinical curative effect of external application of Rebi ointment in treating rhe ...	Observation on the clinical curative effect of external application of Rebi ointment in treating rhe ...	Rheumatoid Arthritis	therapy group:Rebi ointment, Methotrexatetablets, Leflunomidetablets, and Folic acidtablets ;Control ...	Yunnan Provincial Hospital of Traditional Chinese Medicine/The First Affiliated Hospital of Yunnan U ...	NULL	Recruiting	18	70	Both	therapy group:36;Control group:36;		China
6	NCT03649061 (ClinicalTrials.gov)	June 8, 2018	30/7/2018	COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA	Effectiveness of a Combination of Methotrexate and a Step Down Glucocorticoid Regimen (COBRA-Slim) f ...	Arthritis, Rheumatoid	Drug: Etanercept 50 MG/ML;Drug: Leflunomide 10 milligram (MG)	P. Verschueren	Belgium Health Care Knowledge Centre	Active, not recruiting	18 Years	N/A	All	284	Phase 4	Belgium
7	EUCTR2017-004054-41-BE (EUCTR)	07/05/2018	15/03/2018	COBRA-Slim with or without fast access to TNF blockade for remission induction in early RA	CareRA2020: Effectiveness of a combination of Methotrexate and a step down glucocorticoid regimen (C ...	early active Rheumatoid Arthritis, previously untreated with DMARDs MedDRA version: 20.0;Level: PT;C ...	Product Name: etanercept INN or Proposed INN: ETANERCEPT INN or Proposed INN: LEFLUNOMIDE	University Hospitals Leuven	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	440	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Belgium
8	NCT03449758 (ClinicalTrials.gov)	March 5, 2018	8/2/2018	Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis	Effect of Sarilumab on Patient-reported Outcomes in Patients With Moderately to Severely Active Rheu ...	Rheumatoid Arthritis	Drug: SARILUMAB;Drug: Azathioprine;Drug: Chloroquine;Drug: Hydroxychloroquine;Drug: Leflunomide;Drug ...	Sanofi	Regeneron Pharmaceuticals	Completed	18 Years	N/A	All	84	Phase 4	France
9	NCT04022525 (ClinicalTrials.gov)	February 1, 2018	15/7/2019	Assessment of LeflunomideEfficacy and Hepatotoxicity in Patients With Rheumatoid Arthritis Through P ...	Assessment of LeflunomideEfficacy and Hepatotoxicity in Patients With Rheumatoid Arthritis Through P ...	Rheumatoid Arthritis	Drug: Leflunomide 20Mg Tab	Assiut University	NULL	Completed	18 Years	N/A	All	80		Egypt
10	EUCTR2011-004720-35-NL (EUCTR)	22/03/2017	22/02/2017	A multicenter, randomized, open-label, blinded-assessor, phase 4 study in patients with early rheuma ...	A multicenter, randomized, open-label, blinded-assessor, phase 4 study in patients with early rheuma ...	Rheumatoid arthritis (RA) MedDRA version: 19.1;Level: PT;Classification code 10039073;Term: Rheumato ...	Trade Name: Cimzia Trade Name: Orencia Trade Name: RoActemra INN or Proposed INN: METHOTREXATE INN or Pr ...	The Karolinska Institute, ClinTRID	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 4	Finland;Denmark;Norway;Iceland;Netherlands;Sweden

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