46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

3 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04246762 (ClinicalTrials.gov)	April 6, 2021	27/1/2020	Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on ...	A Phase 1, Open-label, Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Singl ...	Rheumatoid Arthritis	Drug: Olokizumab;Drug: Omeprazole;Drug: Caffeine;Drug: Warfarin + Vitamin K;Drug: Midazolam	R-Pharm International, LLC	IQVIA RDS Ireland Ltd;Thermo Fisher Scientific	Recruiting	18 Years	70 Years	All	15	Phase 1	Bulgaria;Moldova, Republic of
2	NCT01636557 (ClinicalTrials.gov)	October 11, 2012	6/7/2012	A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities ...	A Phase I, Open-label, Drug Interaction Study to Evaluate the Effect of a Single-dose of CNTO 136 (S ...	Arthritis, Rheumatoid	Drug: Sirukumab;Drug: Midazolam;Drug: Warfarin;Drug: Vitamin K;Drug: Omeprazole;Drug: Caffeine	Janssen Research & Development, LLC	NULL	Completed	18 Years	65 Years	All	12	Phase 1	Germany;Korea, Republic of;Moldova, Republic of;South Africa
3	NCT01311622 (ClinicalTrials.gov)	March 2011	21/2/2011	Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in Healthy Subjects	An Open-Label, Single Centre Study to Assess the Pharmacokinetics and Pharmacodynamics of WarfarinWh ...	Rheumatoid Arthritis;Healthy Subjects	Drug: warfarin;Drug: fostamatinib	AstraZeneca	NULL	Completed	18 Years	55 Years	Both	15	Phase 1	United Kingdom

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