49. 全身性エリテマトーデス Systemic lupus erythematosus Clinical trials / Disease details

臨床試験数 : 946 / 薬物数 : 722 - (DrugBank : 186) / 標的遺伝子数 : 117 - 標的パスウェイ数 : 199

20 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03492255 (ClinicalTrials.gov)	April 12, 2018	16/3/2018	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	Systemic Lupus Erythematosus (SLE)	Drug: Cyclophosphamide;Drug: Methylprednisolone;Drug: Prednisone;Drug: Mycophenolate Mofetil	University of Sao Paulo General Hospital	Fundação de Amparo à Pesquisa do Estado de São Paulo	Terminated	18 Years	N/A	All	49	N/A	Brazil
2	NCT03030976 (ClinicalTrials.gov)	March 2017	22/1/2017	A Study of CD19 Redirected Autologous T Cells for CD19 Positive Systemic Lupus Erythematosus (SLE)	An Open-labeled, Uncontrolled, Single-arm Pilot Study to Evaluate Cellular Immunotherapy Using CD19- ...	Systemic Lupus Erythematosus (SLE)	Drug: cyclophosphamide;Drug: anti-CD19-CAR-T cells	Shanghai GeneChem Co., Ltd.	RenJi Hospital	Recruiting	18 Years	69 Years	All	5	Phase 1	China
3	NCT02080195 (ClinicalTrials.gov)	September 13, 2016	28/2/2014	Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythe ...	A Phase I/II Study of Nonmyeloablative Conditioning and Transplantation of Human Leukocyte Antigen ( ...	Lupus Erythematosus;Graft-versus-host Disease	Drug: Cyclophosphamide;Drug: Fludarabine;Drug: Tacrolimus;Drug: Mycophenolate Mofetil;Drug: Rabbit ant ...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Maryland Stem Cell Research Fund	Terminated	18 Years	75 Years	All	1	Phase 1/Phase 2	United States
4	ChiCTR-ONC-15007547	2015-12-05	2015-12-04	Clinical theraputic effect of traditional Chinese medicine on systemic lupus erythematosus: a multic ...	Study of the clinical theraputic effect of traditional Chinese medicine on systemic lupus erythemato ...	systemic lupus erythematosus	The combination of Chinese and western group:Traditional Chinese medicine combined western medicine; ...	Zhejiang Chinese Medical University	NULL	Recruiting	18	60	Both	The combination of Chinese and western group:264;Treating by Western Medicine group:264;		China
5	NCT02444728 (ClinicalTrials.gov)	July 2015	12/5/2015	Cyclophosphamide and Hydroxychloroquine for Thrombocytopenia in SLE	Cyclophosphamideand Hydroxychloroquine for the Treatment of Severe Thrombocytopenia in Systemic Lupu ...	Thrombocytopenia	Drug: Hydroxychloroquine;Drug: Cyclophosphamide;Drug: Azathioprine;Drug: Methylprednisolone	Chinese SLE Treatment And Research Group	Peking Union Medical College Hospital	Recruiting	18 Years	70 Years	All	220	Phase 3	China
6	NCT01060410 (ClinicalTrials.gov)	May 2010	1/2/2010	Exploration of Genotype Based Personalized Prescription of Cyclophosphamidein Systemic Lupus Erythem ...	Exploration of Genetic Polymorphisms Related to Individual Variations of Side Effects of Cyclophosph ...	Lupus Erythematosus, Systemic;Adverse Effects	Genetic: Polymorphism Analysis;Drug: Cyclophosphamide;Other: Pharmacokinetic analysis	Sun Yat-sen University	First Affiliated Hospital, Sun Yat-Sen University	Completed	12 Years	80 Years	Both	222	N/A	China
7	NCT00626197 (ClinicalTrials.gov)	February 2008	20/2/2008	A Study to Evaluate Ocrelizumab in Patients With Nephritis Due to Systemic Lupus Erythematosus (BELO ...	A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Evaluate the Ef ...	Lupus Nephritis;Systemic Lupus Erythematosus	Drug: corticosteroids;Drug: cyclophosphamide;Drug: mycophenolate mofetil;Drug: ocrelizumab;Drug: plac ...	Genentech, Inc.	Roche Pharma AG	Completed	16 Years	N/A	All	381	Phase 3	United States
8	EUCTR2005-003957-28-DK (EUCTR)	21/12/2006	20/11/2006	FIVE-YEAR SINGLE-BLIND, PHASE III EFFECTIVENESS RANDOMISEDACTIVELY CONTROLLED CLINICAL TRIAL IN NEW ...	FIVE-YEAR SINGLE-BLIND, PHASE III EFFECTIVENESS RANDOMISEDACTIVELY CONTROLLED CLINICAL TRIAL IN NEW ...	SYSTEMIC LUPUS ERYTHEMATOSUS NEPHRITIS MedDRA version: 8.1;Level: LLT;Classification code 10029142;T ...	Product Name: Cyclophosphamide Product Name: Cyclophosphamide	Istituto Giannina Gaslini	NULL	Not Recruiting			Female: yes Male: yes	141	Phase 3	Denmark;Italy
9	NCT00336414 (ClinicalTrials.gov)	June 2006	12/6/2006	Five-Year Actively Controlled Clinical Trial in New Onset Juvenile Systemic Lupus Erythematosus Neph ...	Five-Year Single-Blind, Phase III Effectiveness Randomised Actively Controlled Clinical Trial in New ...	Systemic Lupus Erythematosus Nephritis	Drug: cyclophosphamide -prednisone-azathioprine	Istituto Giannina Gaslini	NULL	Withdrawn	1 Year	18 Years	All	0	Phase 3	Italy
10	EUCTR2005-003957-28-IT (EUCTR)	02/05/2006	09/05/2006	FIVE-YEAR SINGLE-BLIND, PHASE II EFFECTIVENESS RANDOMISED ACTIVELY CONTROLLED CLINICAL TRIAL IN NEW ...	FIVE-YEAR SINGLE-BLIND, PHASE II EFFECTIVENESS RANDOMISED ACTIVELY CONTROLLED CLINICAL TRIAL IN NEW ...	New onset juvenile sistemic lupus erythematosus nephritis MedDRA version: 6.1;Level: PT;Classificati ...	INN or Proposed INN: Azathioprine INN or Proposed INN: Methylprednisolone INN or Proposed INN: Prednis ...	ISTITUTO GIANNINA GASLINI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	141	Phase 2	Italy

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