49. 全身性エリテマトーデス Systemic lupus erythematosus Clinical trials / Disease details

臨床試験数 : 946 / 薬物数 : 722 - (DrugBank : 186) / 標的遺伝子数 : 117 - 標的パスウェイ数 : 199

25 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04702256 (ClinicalTrials.gov)	December 9, 2021	30/11/2020	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicen ...	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicen ...	Lupus Nephritis;Systemic Lupus Erythematosus (SLE)	Drug: Obinutuzumab administration;Drug: Administration of Methylprednisolone + Prednisone + Mycopheno ...	Assistance Publique - Hôpitaux de Paris	Roche Pharma AG	Recruiting	14 Years	N/A	All	196	Phase 3	France
2	NCT05057481 (ClinicalTrials.gov)	September 15, 2021	16/9/2021	Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematos ...	Reappraisal of Second-line Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Ery ...	Autoimmune Hemolytic Anemia;Systemic Lupus Erythematosus	Drug: Mycophenolate Mofetil 500mg;Drug: Rituximab	Assiut University	NULL	Active, not recruiting	18 Years	N/A	All	30	Phase 3	Egypt
3	NCT03492255 (ClinicalTrials.gov)	April 12, 2018	16/3/2018	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	Systemic Lupus Erythematosus (SLE)	Drug: Cyclophosphamide;Drug: Methylprednisolone;Drug: Prednisone;Drug: Mycophenolate Mofetil	University of Sao Paulo General Hospital	Fundação de Amparo à Pesquisa do Estado de São Paulo	Terminated	18 Years	N/A	All	49	N/A	Brazil
4	NCT02080195 (ClinicalTrials.gov)	September 13, 2016	28/2/2014	Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythe ...	A Phase I/II Study of Nonmyeloablative Conditioning and Transplantation of Human Leukocyte Antigen ( ...	Lupus Erythematosus;Graft-versus-host Disease	Drug: Cyclophosphamide;Drug: Fludarabine;Drug: Tacrolimus;Drug: Mycophenolate Mofetil;Drug: Rabbit ant ...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Maryland Stem Cell Research Fund	Terminated	18 Years	75 Years	All	1	Phase 1/Phase 2	United States
5	JPRN-UMIN000025328	2015/12/05	25/12/2016	A Randomized Open-label Study to Evaluate the Efficacy and Safety of Tacrolimus and Corticosteroids ...	A Randomized Open-label Study to Evaluate the Efficacy and Safety of Tacrolimus and Corticosteroids ...	systemic lupus erythematosus	Tacrolimus Mycophenolate Mofetil	The University of Hong Kong	NULL	Recruiting	18years-old	75years-old	Male and Female	200	Not selected	Japan,Asia(except Japan)
6	NCT01773616 (ClinicalTrials.gov)	April 2015	1/11/2012	Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis	Phase 3 Open Label Randomised Multicentre Controlled Trial of Rituxmab and MycophenolateMofetil With ...	Systemic Lupus Erythematosus, Lupus Nephritis	Drug: Oral prednisolone;Drug: Rituximab;Drug: Mycophenolate mofetil;Drug: Methyl prednisolone	Imperial College London	Karolinska Institutet;Ohio State University;Dutch Working Party on Systemic Lupus Erythematosus;EULA ...	Terminated	12 Years	75 Years	All	24	Phase 3	United Kingdom
7	NCT01946880 (ClinicalTrials.gov)	November 20, 2013	13/9/2013	Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)	An Investigator-Initiated, Phase II, Randomized, Withdrawal Study of MycophenolateMofetil (MMF) in P ...	Systemic Lupus Erythematosus;SLE	Drug: Mycophenolate Mofetil;Drug: Hydroxychloroquine or Chloroquine;Drug: Prednisone	National Institute of Allergy and Infectious Diseases (NIAID)	Autoimmunity Centers of Excellence;Rho Federal Systems Division, Inc.	Terminated	18 Years	70 Years	All	102	Phase 2	United States
8	EUCTR2009-017273-38-ES (EUCTR)	26/10/2010	27/07/2010	Estudio fase III, multicéntrico, aleatorizado, abierto de grupos paralelos para comparar la eficacia ...	Estudio fase III, multicéntrico, aleatorizado, abierto de grupos paralelos para comparar la eficacia ...	Nefritis lúpico tipo III,IV y V. MedDRA version: 9;Level: LLT;Classification code 10029142;Term: Nep ...	Product Name: Ciclosporina Product Code: Csa INN or Proposed INN: CICLOSPORINA Other descriptive name: ...	Manuel Praga Terente	NULL	Not Recruiting			Female: yes Male: yes	38		Spain
9	NCT01085097 (ClinicalTrials.gov)	September 1, 2010	4/3/2010	A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis ...	A Phase 2a, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Safety, ...	Lupus Nephritis	Drug: Laquinimod;Drug: Mycophenolate Mofetil;Drug: Prednisolone /Prednisone;Drug: Placebo;Drug: Methyl ...	Teva Branded Pharmaceutical Products R&D, Inc.	NULL	Completed	18 Years	75 Years	All	46	Phase 2	United States;Canada;France;Russian Federation;United Kingdom
10	NCT01112215 (ClinicalTrials.gov)	December 2009	26/4/2010	Enteric-coated Mycophenolate Sodium Versus Azathioprine for the Extra-renal Lupus Manifestations	Randomized Controlled Trial to Evaluate the Efficacy of Enteric-coated MycophenolateSodium Versus Az ...	Systemic Lupus Erythematosus	Drug: Azathioprine;Drug: Enteric-Coated Mycophenolate Sodium	Hospital Universitari Vall d'Hebron Research Institute	NULL	Completed	18 Years	65 Years	Both	240	Phase 4	Spain

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