56. ベーチェット病 Behcet disease Clinical trials / Disease details
臨床試験数 : 76 / 薬物数 : 110 - (DrugBank : 32) / 標的遺伝子数 : 36 - 標的パスウェイ数 : 116
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2100045463 | 2021-05-01 | 2021-04-15 | Efficacy and safety of Adalimumab in refractory intestinal Behcet’s disease: A single-center, interventional, open-label, single-arm study | Efficacy and safety of Adalimumab in refractory intestinal Behcet’s disease: A single-center, interventional, open-label, single-arm study | intestinal Beh?et's disease | One-armed intervention group:adalimumab; | The First Affiliated Hospital, College of Medicine, Zhejiang University | NULL | Recruiting | 18 | 70 | Both | One-armed intervention group:30; | Phase 4 | China |
| 2 | ChiCTR1900027147 | 2020-01-01 | 2019-11-02 | Efficacy and safety of adalimumab in Behcet's disease-related uveitis | Efficacy and safety of adalimumab in Behcet's disease-related uveitis | Behcet's disease-related uveitis | 1:Adalimumab; | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University | NULL | Pending | Both | 1:30; | Phase 4 | China | ||
| 3 | EUCTR2017-000845-39-IT (EUCTR) | 12/05/2017 | 08/06/2021 | Effectiveness of anti TNFalpha agents in Behcet¿s disease | THE ROLE OF ANTI TNF ALPHA AGENTS IN BEH¿ET¿S DISEASE REFRACTORY TO STANDARD OF CARE THERAPIES: MULTICENTER RANDOMIZED CONTROLLED PROSPECTIVE PARALLEL GROUP SINGLE-BLIND TRIAL TO EVALUATE THE 6 MONTH EFFECTIVENESS OF EITHER INFLIXIMAB OR ADALIMUMAB - FARM12LTAT | BEH¿ET¿S DISEASE REFRACTORY TO STANDARD OF CARE THERAPIES MedDRA version: 20.0;Level: LLT;Classification code 10004215;Term: Behcets disease;System Organ Class: 100000004866;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Trade Name: HUMIRA - 40 MG SOLUZIONE INIETTABILE USO SOTTOCUTANEO 1 SIRINGA PRERIEMPITA 0.8 ML + 1 TAMPONE IMBEVUTO DI ALCOL IN UN BLISTER Product Name: HUMIRA Product Code: HUMIRA INN or Proposed INN: ADALIMUMAB Trade Name: INFLECTRA - 100 MG - POLVERE PER CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) - 1 FLACONCINO Product Name: INFLECTRA Product Code: INFLECTRA INN or Proposed INN: INFLIXIMAB Trade Name: MEDROL - 4 MG COMPRESSE 30 COMPRESSE Product Name: MEDROL INN or Proposed INN: METILPREDNISOLONE Trade Name: SOLU MEDROL - 500 MG/8 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE DI POLVERE DA 500 MG+ FIALA SOLVENTE DA 8 ML Product Name: SOLU MEDROL Product Code: SOLU MEDROL INN or Proposed INN: METILPREDNISOLONE SODIO SUCCINATO Trade Name: SOLU MEDROL - 40 MG/ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE A DOPPIA CAMERA DA 40 MG/ML Product Name: SOLU MEDROL Product Code: SOLU MEDROL | AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 46 | Phase 3 | Italy | ||
| 4 | JPRN-UMIN000012469 | 2013/12/02 | 02/12/2013 | Comparison of Adalimumab and Steroid in Intestinal Behcet's disease | Comparison of Adalimumab and Steroid in Intestinal Behcet's disease - Castle Study | Intestinal Behcet's disease | Subcutaneous injection of adalumumab with 160mg at 0 week, 80mg at 2 weeks and 40mg every other week after at 4 weeks continuously. Oral administration of prednisolone with 0.6mg/kg/day during from 1 to 2 weeks, and tapering off until 12 weeks with decreasing dosage 5mg/kg/week approximately | Castle Study Group | NULL | Recruiting | 15years-old | Not applicable | Male and Female | 50 | Not selected | Japan |
| 5 | NCT01243671 (ClinicalTrials.gov) | October 2010 | 17/11/2010 | A Study of Adalimumab in Japanese Subjects With Intestinal Behçet's Disease | A Multi-Center Study of Adalimumab in Japanese Subjects With Intestinal Behçet's Disease | Intestinal Behçet's Disease | Biological: Adalimumab | AbbVie (prior sponsor, Abbott) | Eisai Co., Ltd. | Completed | 15 Years | N/A | All | 20 | Phase 3 | Japan |