6. パーキンソン病 Parkinson disease Clinical trials / Disease details


臨床試験数 : 2,298 薬物数 : 2,202 - (DrugBank : 350) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 202

  
6 trials found
No.TrialIDDate_
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PhaseCountries
1NCT05009199
(ClinicalTrials.gov)
June 24, 20211/7/2021Occupancy of Adenosine A2A Receptors Using the PET Radiotracer [18F]MNI-444A Phase 1 Proof of Principle Study to Evaluate the Occupancy of A2A Receptors Using PET Radiotracer [18F]MNI-444 & Repeated Dosing of Oral Caffeine in Participants Without Parkinson's Disease Who Carry Pathogenic Mutation in the LRRK2 GeneHealthy VolunteerDrug: [18F]MNI-444InvicroNULLRecruiting30 YearsN/AAll3Phase 1United States
2NCT03970798
(ClinicalTrials.gov)
May 22, 201923/5/2019A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or RosuvastatinA Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or RosuvastatinParkinson's DiseaseDrug: Midazolam;Drug: Caffeine;Drug: Rosuvastatin;Drug: KW-6356Kyowa Kirin Co., Ltd.NULLCompleted20 Years44 YearsMale50Phase 1Japan
3JPRN-UMIN000022187
2016/05/0606/05/2016Research on Parkinson's disease pathogenesis based on analysis of caffeine absorption in patients with Parkinson's disease Parkinson's diseasePD group, 200 mg caffeine administration, qd, 1 day
Control group, 200 mg caffeine administration, qd, 1 day
Department of Neurology, Juntendo UniversityNULLComplete: follow-up complete40years-old60years-oldMale and Female20Not applicableJapan
4NCT01738178
(ClinicalTrials.gov)
April 201428/11/2012Caffeine as a Therapy for Parkinson's DiseaseCaffeine as a Therapeutic Agent in Parkinson's DiseaseParkinson's DiseaseDrug: Caffeine;Drug: PlaceboMcGill University Health CenterPontifícia Universidade Católica do Paraná;University of Calgary;University of Newfoundland and Eastern Health;University Health Network, Toronto;UBC Hospital;Movement Disorder Clinic - Deer Lodge Centre;The Ottawa HospitalCompleted45 Years75 YearsAll119Phase 3Brazil;Canada
5NCT01190735
(ClinicalTrials.gov)
August 201026/8/2010Caffeine for Motor Manifestations of Parkinson's DiseaseCaffeine for Motor Manifestations of Parkinson's Disease: An Open-Label Dose-Response Study.Parkinson's DiseaseDrug: Caffeine alkaloidRon PostumaCanadian Institutes of Health Research (CIHR)Completed18 YearsN/ABoth28Phase 2Canada
6NCT00459420
(ClinicalTrials.gov)
April 200711/4/2007Caffeine for Excessive Daytime Somnolence in Parkinson's DiseaseCaffeine for Excessive Daytime Somnolence in Parkinson's DiseaseParkinson's Disease;Excessive Daytime SomnolenceDrug: Caffeine 100-200 mg BID;Drug: placeboRon PostumaCanadian Institutes of Health Research (CIHR);University of TorontoCompleted18 YearsN/ABoth58Phase 2/Phase 3Canada