6. パーキンソン病 Parkinson disease Clinical trials / Disease details
臨床試験数 : 2,298 / 薬物数 : 2,202 - (DrugBank : 350) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 202
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05128175 (ClinicalTrials.gov) | October 29, 2021 | 27/10/2021 | Comparative Bioavailability Study of Carbidopa/Levodopa Extended-Release Tablets Under Fasting and Fed Conditions | An Open-label, Balanced, Randomized, Five-treatment, Five-period, Five-sequence, Multiple Oral Dose, Crossover Comparative Bioavailability Study of Different Strengths of Carbidopa/Levodopa Extended-release Tablets With Carbidopa and Levodopa Tablets in Normal, Healthy Adult Human Subjects Under Fasting and Fed Conditions | Parkinson Disease | Drug: WD-1603 Carbidopa-Levodopa Extended-Release Tablets | Shanghai WD Pharmaceutical Co., Ltd. | NULL | Recruiting | 18 Years | 45 Years | All | 15 | Phase 1 | India |
| 2 | NCT04963894 (ClinicalTrials.gov) | September 1, 2021 | 12/7/2021 | Effects of Home Rehabilitation of Balance Based on Functional Exercises in People With Parkinson's Disease | Effects of Home Rehabilitation of Balance Based on Functional Exercises in People With Parkinson's Disease: Randomized Controlled Trial | Parkinson Disease | Other: Home functional balance physiotherapy;Other: Conventional physiotherapy | University of Valencia | Asociación Parkinson Valencia | Recruiting | 40 Years | 90 Years | All | 112 | N/A | Spain |
| 3 | NCT05220072 (ClinicalTrials.gov) | August 28, 2021 | 18/11/2021 | Mass Balance Recovery and Metabolite Identification of Carbon-14 BIA 28-6156 | An Open Label, Single-dose, Single-period Study Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of Carbon-14 BIA 28-6156 in Healthy Male Subjects | Parkinson Disease | Drug: Carbon-14 BIA 28-6156 | Bial R&D Investments, S.A. | NULL | Completed | 30 Years | 65 Years | Male | 6 | Phase 1 | United Kingdom |
| 4 | NCT04665869 (ClinicalTrials.gov) | March 15, 2021 | 7/12/2020 | Long-term Effects of Combined Balance and Brisk Walking in Parkinson's Disease | Long-term Effects of Combined Balance and Brisk Walking on Alleviating Motor and Non-motor Symptoms in Parkinson's Disease: a Randomized Controlled Trial | Parkinson Disease | Behavioral: Combined balance and brisk walking training;Behavioral: Flexibility and strengthening exercise | The Hong Kong Polytechnic University | NULL | Recruiting | 30 Years | 80 Years | All | 70 | N/A | Hong Kong |
| 5 | NCT04694872 (ClinicalTrials.gov) | January 15, 2021 | 3/1/2021 | The Effects of Telerehabilitation-based Exercise Trainings on Gait and Balance in Parkinson's Patients | The Effects of Telerehabilitation-based Exercise Trainings on Gait and Balance in Parkinson's Patients | Parkinson Disease | Other: Telerehabilitation Based LSVT BIG Exercise Protocol;Other: Telerehabilitation Based Functional Balance and Mobility Exercise | Yeditepe University | Istanbul University-Cerrahpasa | Recruiting | 40 Years | 75 Years | All | 32 | N/A | Turkey |
| 6 | ChiCTR2000038852 | 2020-10-20 | 2020-10-07 | Study on the effect and mechanism of cognitive-cup-tapping-balance-training on fall prevention in community Parkinson's patients: a randomized controlled trial | Study on the effect and mechanism of cognitive-cup-tapping-balance-training on fall prevention in community Parkinson's patients: a randomized controlled trial | Parkinson's disease | dual task training group :cognitive-cup-tapping balance training;single task training group:-cup-tapping balance training;control group:education; | Shanghai University of Sport | NULL | Recruiting | 40 | 80 | Both | dual task training group :29;single task training group:29;control group:29; | N/A | china |
| 7 | NCT04591535 (ClinicalTrials.gov) | September 28, 2020 | 11/9/2020 | PK Study of WD-1603 in Healthy Subjects | An Open Label, Balanced, Randomised, Four-treatment, Four-period, Four-sequence, Single Oral Dose, Crossover PK Study of WD-1603 in Normal, Healthy, Adult Human Subjects Under Fed Conditions | Parkinson Disease | Drug: WD-1603 CARBIDOPA/LEVODOPA EXTENDED-RELEASE TABLETS | Hong Kong WD Pharmaceutical Co., Limited | NULL | Recruiting | 18 Years | 45 Years | All | 8 | Phase 1 | India |
| 8 | NCT04553978 (ClinicalTrials.gov) | September 18, 2020 | 13/9/2020 | A Single Oral Dose, Crossover Comparative PK Study of WD-1603 in Healthy Subjects Under Fasting Conditions | An Open Label, Balanced, Randomised, 2-treatment, 2-period, 2-sequence, Single Oral Dose, Corssover Comparative PK Study of WD-1603 in Normal, Healthy, Adult Human Subjects Under Fasting Conditions | Parkinson Disease | Drug: WD-1603 | Hong Kong WD Pharmaceutical Co., Limited | NULL | Not yet recruiting | 18 Years | 45 Years | All | 8 | Phase 1 | NULL |
| 9 | ChiCTR2000035872 | 2020-09-01 | 2020-08-19 | Effect of repetitive transcranial magnetic stimulation on gait and balance function in patients with Parkinson's disease and Parkinson's syndrome | Effect of repetitive transcranial magnetic stimulation on gait and balance function in patients with Parkinson's disease and Parkinson's syndrome | Parkinson's disease and Parkinson's syndrome | Parkinson's disease observation group:Repetitive transcranial magnetic stimulation+Visual feedback balance training system+Digital treadmill ;Parkinson's disease control group:Visual feedback balance training system+Digital treadmill;Parkinson's syndrome observation group:Repetitive transcranial magnetic stimulation+Visual feedback balance training system+Digital treadmill;Parkinson's syndrome control group:Visual feedback balance training system+Digital treadmill ; | Gansu Provincial Hospital | NULL | Pending | 50 | 85 | Both | Parkinson's disease observation group:28;Parkinson's disease control group:28;Parkinson's syndrome observation group:28;Parkinson's syndrome control group:28; | China | |
| 10 | NCT04513340 (ClinicalTrials.gov) | August 13, 2020 | 12/8/2020 | WD-1603 PK Study Under Fasting and Fed Conditions in Healthy Subjects | AN OPEN LABEL, BALANCED, RANDOMISED, FOUR-TREATMENT, FOUR-PERIOD, FOUR-SEQUENCE, SINGLE INTRA-ORAL AND ORAL DOSE, CROSSOVER PHARMACOKINETICS STUDY OF WD-1603 EXTENDED-RELEASE CARBIDOPA/LEVODOPA TABLETS 25/100MG IN NORMAL, HEALTHY, ADULT HUMAN SUBJECTS UNDER FASTING AND FED CONDITIONS | Parkinson Disease | Drug: WD-1603 CARBIDOPA and LEVODOPA EXTENDED-RELEASE TABLETS | Hong Kong WD Pharmaceutical Co., Limited | NULL | Recruiting | 18 Years | 45 Years | All | 8 | Phase 1 | India |
| 11 | ChiCTR2000034323 | 2020-08-01 | 2020-07-02 | The effect and correlation of rehabilitation training mode combined with visual feedback balance system and digital treadmill on three-dimensional Gait kinematics and diffusion tensor imaging in patients with early and mid period Parkinson's disease | The effect of rehabilitation training mode combined with visual feedback balance system and digital treadmill on Gait kinematics and diffusion tensor imaging in patients with early and mid period Parkinson's disease | Parkinson's disease | experimental group:Combined Rehabilitation Training of visual feedback balance system and digital treadmill;control group:Traditional Gait Balance Rehabilitation Training; | Xianhui Feng | NULL | Pending | Both | experimental group:30;control group:30; | China | |||
| 12 | NCT04146454 (ClinicalTrials.gov) | October 14, 2019 | 16/10/2019 | Smartphone-based Wearable Telerehabilitation | A New Smartphone-based Wearable Telerehabilitation System for People With Parkinson's Disease | Parkinson Disease | Other: Smartphone-based balance exercises | University of Houston | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Enrolling by invitation | 50 Years | 75 Years | All | 44 | N/A | United States |
| 13 | NCT03939559 (ClinicalTrials.gov) | June 10, 2019 | 3/5/2019 | The Efficiency of Home Based Dual Task Training in Parkinson Disease | The Efficiency of Home Based Dual Task Training in Parkinson Disease | Parkinson Disease | Procedure: Static, dynamic and functional balance exercises;Procedure: Static, dynamic and functional balance exercises with dual task | Istanbul University-Cerrahpasa | NULL | Not yet recruiting | 30 Years | 80 Years | All | 60 | N/A | NULL |
| 14 | NCT04420910 (ClinicalTrials.gov) | April 15, 2019 | 4/6/2020 | Non-motor Symptoms, Balance, Muscle Strength, and Functional Mobility in Patients With Parkinson's Disease | Investigation of Non-motor Symptoms, Balance, Muscle Strength, and Functional Mobility in Patients With Parkinson's Disease | Parkinson Disease;Balance;Muscle Strength;Mobility;Non-motor Symptoms | Other: Non-Motor Symptoms;Other: Balance;Other: Lower Limb Strength;Other: Functional mobility | Ankara Yildirim Beyazit University | NULL | Completed | 50 Years | 65 Years | All | 44 | Turkey | |
| 15 | NCT03661125 (ClinicalTrials.gov) | April 11, 2019 | 4/9/2018 | SRC Inhibition as a Potential Target for Parkinson's Disease Psychosis | A Randomised, Balanced, Double-blind Two-way Crossover Design Study to Evaluate the Effects of SRC Kinase Inhibitor, Saracatinib, on Brain Activity Associated With Visual Processing in Patients With Parkinson's Disease Psychosis. | Parkinson Disease Psychosis | Drug: Saracatinib;Drug: Placebo Oral Tablet | King's College London | AstraZeneca;King's College Hospital NHS Trust | Recruiting | 40 Years | N/A | All | 30 | Early Phase 1 | United Kingdom |
| 16 | NCT03942172 (ClinicalTrials.gov) | November 27, 2018 | 6/5/2019 | Treatment of Balance Disorders in Parkinson's Patients Using SpotOn Balance Glasses | Treatment of Balance Disorders in Parkinson's Patients Using SpotOn Balance Glasses | Parkinson Disease | Device: SpotOn balance glasses | SpotOn Therapeutics Ltd. | NULL | Suspended | 30 Years | N/A | All | 50 | N/A | Israel |
| 17 | NCT04048291 (ClinicalTrials.gov) | October 15, 2018 | 9/10/2018 | Efficacy of Brisk Walking in Parkinson's Disease | Efficacy of Brisk Walking on Improving Balance and Gait Performance, and Functional Mobility in Parkinson's Disease - a Randomized Controlled Trial | Parkinson Disease | Behavioral: Brisk walking and balance training;Behavioral: Upper limb exercise | The Hong Kong Polytechnic University | NULL | Completed | 30 Years | N/A | All | 80 | N/A | Hong Kong |
| 18 | NCT03587168 (ClinicalTrials.gov) | July 20, 2018 | 3/7/2018 | The Reliability, Validity, and Responsiveness of the Timed 360° Turn Test in Patients With Parkinson's Disease | The Reliability, Validity, and Responsiveness of the Timed 360° Turn Test in Patients With Parkinson's Disease | Parkinson Disease | Other: the timed 360° turn test;Other: Berg Balance Scale;Other: Four Square Step Test;Other: Functional Reach Test;Other: Trunk Impairment Scale;Other: Timed Up and Go Test;Other: Hoehn and Yahr Scale;Other: Unified Parkinson's Disease Rating Scale | Gazi University | NULL | Completed | 40 Years | N/A | All | 86 | Turkey | |
| 19 | JPRN-jRCTs052180158 | 19/07/2018 | 25/03/2019 | The effect of rehabilitation robots for patients with Parkinson's disease. | A study on the effectiveness of balance rehabilitation support robot (balance exercise assist robot) for Parkinson's patient. | Parkinson's Disease;D010300 | Robot group: The participants performs twelve per a session, 2sessions per a week for 8 weeks. Control group: The participants receives balance exercise by physical therapist twice a week for 8 weeks. | Domen Kazuhisa | NULL | Recruiting | >= 40age old | <= 80age old | Both | 50 | N/A | Japan |
| 20 | JPRN-UMIN000033454 | 2018/07/01 | 20/07/2018 | A study on the effectiveness of balance rehabilitation support robot (balance exercise assist robot) for Parkinson's patient. | A study on the effectiveness of balance rehabilitation support robot (balance exercise assist robot) for Parkinson's patient. - A study on the effectiveness of balance rehabilitation support robot (balance exercise assist robot) for Parkinson's patient. | Parkinson's Disease | robot assisted balance training (RABT) The group is taken 40-minute / session, twice a week during 8-weeks. Total intervention sessions are 16. traditional balance training (TBT) The group is taken 40-minute / session, twice a week during 8-weeks. Total intervention sessions are 16. | Hyogo College of Medicine | NULL | Recruiting | 40years-old | 80years-old | Male and Female | 50 | Not selected | Japan |
| 21 | NCT03532984 (ClinicalTrials.gov) | June 1, 2018 | 27/4/2018 | Beam Walking Across the Lifespan for Falls Prediction | Beam Walking to Assess Dynamic Balance in Health and Disease: A Protocol for the 'BEAM' Multi-center Observational Study | Aging;Parkinson Disease;Stroke;Dementia;Diagnoses Disease;Cognitive Impairment;Postural; Defect | Diagnostic Test: Beam test to predict falls | University Medical Center Groningen | Dokkyo Medical University;University of Potsdam;Somogy Megyei Kaposi Mór Teaching Hospital;University of Sao Paulo | Unknown status | 20 Years | 80 Years | All | 432 | Brazil;Germany;Hungary;Japan;Netherlands | |
| 22 | NCT04228887 (ClinicalTrials.gov) | May 4, 2018 | 5/8/2019 | Effects of Inspiratory Muscle Training in Patients With Parkinson's Disease | Effects of Inspiratory Muscle Training on Postural Stability, Mobility, Activities of Daily Living, Quality of Life and Respiratory Function in Patients With Parkinson's Disease | Parkinson Disease | Diagnostic Test: Respiratory Muscle Strength;Device: Balance Training;Device: Inspiratory Muscle Training | Bezmialem Vakif University | NULL | Completed | 60 Years | 85 Years | All | 30 | N/A | Turkey |
| 23 | NCT03827746 (ClinicalTrials.gov) | April 1, 2018 | 31/1/2019 | The Effect of Kinesiophobia on Physical Activity, Balance and Falling in Parkinson's Disease Patients | The Effect of Kinesiophobia on Physical Activity, Balance and Falling in Parkinson's Disease Patients | Parkinson Disease;Kinesiophobia;Physical Activity;Balance;Falling | Other: Tampa Kinesiophobia Scale, Berg-Balance Test, International Physical Activity Questionnaire-Short Form, Falls Efficacy Scale | Istanbul Kültür University | Marmara University;Istanbul University-Cerrahpasa | Completed | 40 Years | 85 Years | All | 60 | Turkey | |
| 24 | NCT03882398 (ClinicalTrials.gov) | February 15, 2018 | 11/3/2019 | Effects of a High-intensity Progressive-cycle Program on Quality of Life and Motor Symptomatology in Parkinson's Disease | Effects of a High-intensity Progressive-cycle Program on Quality of Life and Motor Symptomatology in Parkinson's Disease Population: a Pilot Randomized Controlled Trial | Parkinson Disease;Exercise;Physical Activity;Quality of Life | Other: Balance;Other: Endurance | University of Vigo | NULL | Completed | 60 Years | 80 Years | All | 14 | N/A | Spain |
| 25 | NCT03232996 (ClinicalTrials.gov) | November 1, 2017 | 24/7/2017 | Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease. | Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease. | Parkinson Disease;Parkinson | Other: Computer game based balance and walking rehabilitation for individuals with Parkinson's Disease | University of Manitoba | NULL | Completed | 55 Years | 70 Years | All | 30 | N/A | Canada |
| 26 | ChiCTR-IPR-17011875 | 2017-08-01 | 2017-07-05 | Effects of Baduanjin Combined Balance Training on Gait and Posture Control of Patients with Mild and Moderate Parkinson's Disease | Effects of Baduanjin Combined Balance Training on Gait and Posture Control of Patients with Mild and Moderate Parkinson's Disease | Parkinson's Disease | Control group:Conventional drug therapy;Baduanjin group:Baduanjin aerobic exercise;Balance function training group:Balance function training group; | Affiliated Lianyungang Hospital of Xuzhou Medical University | NULL | Pending | 40 | 80 | Both | Control group:30;Baduanjin group:30;Balance function training group:30; | China | |
| 27 | NCT03119194 (ClinicalTrials.gov) | January 27, 2017 | 13/4/2017 | Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-BIA 9-1067 | An Open-Label, Single-Dose, Single-Period Study Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-BIA 9-1067 in Healthy Male Subjects | Parkinson Disease | Drug: [14C]-BIA 9-1067 | Bial - Portela C S.A. | NULL | Completed | 30 Years | 65 Years | Male | 7 | Phase 1 | United Kingdom |
| 28 | NCT02879136 (ClinicalTrials.gov) | December 2016 | 23/6/2016 | TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Disease | TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Disease: A Single Center, Randomized Pilot Study | Parkinson's Disease, Idiopathic | Drug: Methylphenidate;Other: Physical Therapy;Drug: Atomoxetine | Hubert Fernandez | NULL | Recruiting | 18 Years | 90 Years | All | 42 | Early Phase 1 | United States |
| 29 | NCT02935842 (ClinicalTrials.gov) | October 1, 2016 | 18/8/2016 | Evaluation of Intensive Language Therapy | Effectiveness of High-frequency Specific Speech Therapy on Verbal Fluency Decline and/ or Verbal Apraxia in Patients With Parkinson's Disease With and Without Deep Brain Stimulation (DBS) - a Randomized Controlled Single-blinded Trial | Parkinson's Disease | Other: Specific SL-therapy;Other: Rhythmic Balance-Movement Training (rBMT) | University Hospital, Basel, Switzerland | NULL | Completed | 45 Years | 80 Years | All | 38 | N/A | Switzerland |
| 30 | NCT02910102 (ClinicalTrials.gov) | October 2016 | 16/9/2016 | Study Evaluating Intepirdine (RVT-101) on Gait and Balance in Subjects With Dementia | A Phase 2, Double-blind, Randomized, Placebo-controlled Crossover Study Evaluating the Effect of RVT-101 on Gait and Balance in Subjects With Alzheimer's Disease, Dementia With Lewy Bodies, or Parkinson's Disease Dementia | Alzheimer's Disease;Dementia With Lewy Bodies;Parkinson's Disease Dementia | Drug: RVT-101 35 mg;Drug: Placebo | Axovant Sciences Ltd. | NULL | Completed | 50 Years | 89 Years | All | 38 | Phase 2 | United States |
| 31 | NCT02812147 (ClinicalTrials.gov) | May 2016 | 25/5/2016 | Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson Disease | Effect of L-Dihydoxyphenylserine (L-DOPS, Northera) a Central and Peripheral Norepinephrine Agent on Locomotion, Postural Stability (Balance), and Fall Risk Reduction in Parkinson Disease (PD) | Parkinson Disease | Drug: L-DOPS;Drug: Placebo | St. Joseph's Hospital and Medical Center, Phoenix | Arizona State University, Tempe | Active, not recruiting | 30 Years | 83 Years | All | 20 | Phase 2 | United States |
| 32 | NCT02488265 (ClinicalTrials.gov) | July 1, 2015 | 21/5/2015 | Protocol: Balance Training in Parkinson's Disease | Randomized Controlled Trial Protocol: Balance Training With Rhythmical Cues to Improve and Maintain Balance Control in Parkinson's Disease | Parkinson Disease | Other: Balance Training;Other: Screening to prevent falls | University of Sao Paulo General Hospital | NULL | Completed | 50 Years | 70 Years | All | 150 | N/A | Brazil |
| 33 | JPRN-UMIN000016591 | 2015/04/01 | 20/02/2015 | Clinical trial of balance exercise "Assist" | Stroke, Parkinson disease, Osteoarthrosis | use of balance exercise assist ordinary balance exercise | Juntendo University | NULL | Complete: follow-up complete | 20years-old | 75years-old | Male and Female | 40 | Not applicable | Japan | |
| 34 | NCT02696603 (ClinicalTrials.gov) | March 2015 | 23/2/2016 | Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower) | Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower) | Parkinson Disease;Neurodegenerative Diseases;Movement Disorders;Central Nervous System Diseases;Brain Diseases;Basal Ganglia Diseases;Parkinsonian Disorders | Behavioral: Participant self-assessment surveys;Behavioral: Phonation;Behavioral: Gait and balance;Behavioral: Memory;Behavioral: Dexterity;Behavioral: Participant open-response writing;Other: Parkinson mPower mobile application | Sage Bionetworks | Robert Wood Johnson Foundation | Recruiting | 18 Years | N/A | All | 20000 | N/A | United States |
| 35 | NCT02777060 (ClinicalTrials.gov) | September 2014 | 8/6/2015 | Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures | Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures | Diabetes;Cancer;Multiple Sclerosis;Arthritis;Parkinson's Disease;Cognitive Disorders;Brain Injury;Stroke | Procedure: Exergame;Procedure: Home based balance training | University of Arizona | NULL | Recruiting | 18 Years | N/A | Both | 200 | N/A | United States |
| 36 | NCT02230267 (ClinicalTrials.gov) | August 2014 | 27/8/2014 | High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease | High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease | Parkinson's Disease | Other: High intensity exercise and balance training;Other: Usual care arm exercise | University of Nevada, Las Vegas | NULL | Completed | 45 Years | 85 Years | Both | 27 | Phase 2 | United States |
| 37 | NCT02206620 (ClinicalTrials.gov) | July 2014 | 29/7/2014 | Effects of Cholinergic Augmentation on Measures of Balance and Gait | Effects of Cholinergic Augmentation on Measures of Balance and Gait | Parkinson's Disease | Drug: Donepezil | Oregon Health and Science University | Michael J. Fox Foundation for Parkinson's Research | Completed | 30 Years | N/A | All | 49 | Phase 2 | United States |
| 38 | NCT03314597 (ClinicalTrials.gov) | April 2, 2014 | 15/10/2017 | Instrumental or Physical-Exercise Rehabilitation of Balance in Parkinson's Disease? (IPER-PD) | Instrumental or Physical-exercise Rehabilitation of Balance Improve Both Balance and Gait in Parkinson's Disease. | Parkinson's Disease;Rehabilitation | Other: Balance exercise;Other: Mobile platform exercise | University of Pavia | Fondazione Salvatore Maugeri | Completed | 50 Years | 85 Years | All | 38 | N/A | NULL |
| 39 | NCT01521117 (ClinicalTrials.gov) | December 2011 | 12/1/2012 | The Effect of Donepezil on Gait and Balance in Parkinson's Disease | A Randomized, Double-blind, Placebo Controlled, Crossover Study to Evaluate the Effect of Donepezil on Gait and Balance in Parkinson's Disease | Parkinson's Disease | Drug: Donepezil | Oregon Health and Science University | NULL | Recruiting | N/A | N/A | Both | 12 | Phase 4 | United States |
| 40 | NCT02302144 (ClinicalTrials.gov) | December 2011 | 24/11/2014 | A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease | A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease | Parkinson Disease | Behavioral: Balance & Strengthening Exercises | Boston University Charles River Campus | NULL | Completed | 18 Years | N/A | All | 32 | N/A | United States |
| 41 | NCT02253563 (ClinicalTrials.gov) | June 2011 | 24/9/2014 | Resistance Versus Balance Training in Parkinson's Disease | Resistance Training Versus Balance Training to Improve Postural Control in Patients With Parkinson's Disease - a Randomized Controlled Rater Blinded Trial | Parkinson's Disease | Behavioral: Resistance Training;Behavioral: Balance Training | University of Kiel | NULL | Completed | 40 Years | 100 Years | Both | 40 | N/A | NULL |
| 42 | NCT01119131 (ClinicalTrials.gov) | May 2011 | 23/4/2010 | Effects of Vitamin D in Parkinson's Disease (PD) | The Effects of Vitamin D on Balance in Persons With PD | Parkinson Disease;Accidental Falls | Drug: Vitamin D3;Dietary Supplement: calcium;Other: Placebo | VA Office of Research and Development | Oregon Health and Science University | Completed | 50 Years | 99 Years | All | 101 | Phase 2 | United States |
| 43 | NCT01341080 (ClinicalTrials.gov) | December 28, 2010 | 21/4/2011 | Varenicline for Gait and Balance Impairment in Parkinson Disease | Varenicline for the Treatment of Postural and Gait Dysfunction in Parkinson Disease | Parkinson Disease | Drug: Varenicline;Drug: Sugar pill | Rush University Medical Center | NULL | Completed | 40 Years | 90 Years | All | 40 | Phase 2 | United States |
| 44 | NCT01162226 (ClinicalTrials.gov) | September 2010 | 24/6/2010 | Computer-Based Balance Training for People With Parkinson's Disease | PD Wii: Computer-based Gait and Balance Training for Parkinson's Patients. | Parkinson's Disease | Behavioral: gait and balance training program | University of California, San Francisco | National Institute of Neurological Disorders and Stroke (NINDS) | Completed | N/A | N/A | Both | 62 | Phase 2 | United States |
| 45 | NCT01228851 (ClinicalTrials.gov) | August 2010 | 31/8/2010 | Balance Training in Parkinson's Disease Using the Wii Balance Board | A Pilot Study of the Effects of Balance Training Using the Wii Balance Board on Balance and Ambulation in Adults With Parkinson's Disease | Parkinson's Disease | Other: Balance Training | Rehabilitation Institute of Chicago | NULL | Completed | 18 Years | N/A | Both | 10 | N/A | United States |
| 46 | NCT01417598 (ClinicalTrials.gov) | January 2010 | 15/8/2011 | BETA Study: Improving Balance Function in Elderly by Progressive and Specific Training and Physical Activity | Improving Balance Function in Elderly by Progressive and Specific Training and Physical Activity- a Randomized Controlled Study. | Elderly;Parkinsons Disease;Osteoporosis | Other: Gait and balance group training;Other: Nordic walking (only osteoporosis group) | Karolinska Institutet | The Swedish Research Council | Active, not recruiting | 60 Years | N/A | All | 200 | N/A | Sweden |
| 47 | NCT01580787 (ClinicalTrials.gov) | August 2009 | 16/4/2012 | Functional Improvement in Patients With Parkinson's Disease After Training in Real or Virtual Environment | Functional Improvement in Patients With Parkinson's Disease After Training in Real or Virtual Environment | Parkinson´s Disease | Device: Balance Training with Nintendo Wii Fit;Other: Physical Therapy | Sao Camilo University Center | NULL | Completed | 65 Years | 85 Years | Both | 32 | N/A | NULL |
| 48 | NCT00611481 (ClinicalTrials.gov) | October 2008 | 6/2/2008 | Study of Tai Chi Exercise and Balance in Persons With Parkinson's Disease | Phase II Study of Tai Chi Exercise in Relation to Balance in Persons With Parkinson's Disease | Parkinson's Disease | Behavioral: Tai Chi;Behavioral: Strength training;Behavioral: Low-Impact Exercise Control | Oregon Research Institute | National Institute of Neurological Disorders and Stroke (NINDS) | Completed | 40 Years | 85 Years | Both | 195 | Phase 2 | United States |
| 49 | NCT01301651 (ClinicalTrials.gov) | November 2007 | 18/2/2011 | Effects of Virtual Reality Training in Patients With Parkinson's Disease | Effects of Virtual Reality Augmented Balance Training for Postural Control in Patients With Parkinson's Disease | Parkinson's Disease | Behavioral: balance training | National Taiwan University Hospital | National Science Council, Taiwan | Completed | 50 Years | 80 Years | Both | 42 | Phase 1 | Taiwan |