60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details

臨床試験数 : 235 / 薬物数 : 381 - (DrugBank : 83) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 160

17 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03531736 (ClinicalTrials.gov)	May 9, 2018	9/5/2018	T Cell Depleted Allogeneic Hematopoietic Stem Cell TransplantationConditioned With a Reduced Intensi ...	Allogeneic Hematopoietic Stem Cell Transplantationof a/ß T-Lymphocyte Depleted Graft Conditioned Wit ...	Myeloid Diseases	Drug: Antithymocyte globulin (Rabbit);Drug: fludarabine;Radiation: total body irradiation;Drug: cycl ...	Memorial Sloan Kettering Cancer Center	NULL	Recruiting	18 Years	N/A	All	15	Phase 1	United States
2	NCT03192397 (ClinicalTrials.gov)	August 9, 2017	16/6/2017	Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graf ...	A Phase II Trial of Fludarabine/Melphalan/Total Body Irradiation With Post Transplant Cyclophosphami ...	Acute Myeloid Leukemia in Remission;Adult Acute Lymphoblastic Leukemia in Complete Remission;Chronic ...	Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;Drug: Cyclophosphamide;Drug: Fludarabi ...	Roswell Park Cancer Institute	National Cancer Institute (NCI)	Recruiting	18 Years	79 Years	All	30	Phase 2	United States
3	ChiCTR1900023509	2017-01-01	2019-05-31	Allogeneic Hematopoietic Stem Cell Transplantationwith Risk-adapted Conditioning Regimens for Childr ...	Allogeneic Hematopoietic Stem Cell Transplantationwith Risk-adapted Conditioning Regimens for Childr ...	aplastic anemia,Refractory Cytopenia of Childhood	1:Fludarabine150 mg/m2 +Cyclophosphamide200 mg/kg+ Thymoglobuline10mg/kg;2:Fludarabine200 mg/m2 +Cyc ...	Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine	NULL	Recruiting		18	Both	1:50;2:50;3:50;		China
4	NCT02566304 (ClinicalTrials.gov)	November 13, 2015	30/9/2015	Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating P ...	A Two Step Approach to Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantationfor Patie ...	Acute Myeloid Leukemia;Acute Myeloid Leukemia in Remission;Aplastic Anemia;Chronic Myelomonocytic Le ...	Drug: Fludarabine;Radiation: Total-Body Irradiation;Biological: T Cell-Depleted Donor Lymphocyte Inf ...	Sidney Kimmel Cancer Center at Thomas Jefferson University	NULL	Recruiting	18 Years	N/A	All	30	Phase 2	United States
5	NCT01529827 (ClinicalTrials.gov)	February 28, 2012	6/2/2012	Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral B ...	A Phase II Trial of Reduced Intensity Allogeneic Stem Cell Transplantation With Fludarabine, Melphal ...	Accelerated Phase Chronic Myelogenous Leukemia;Adult Acute Lymphoblastic Leukemia in Remission;Adult ...	Drug: fludarabine phosphate;Drug: melphalan;Radiation: total-body irradiation;Drug: tacrolimus;Drug: ...	Roswell Park Cancer Institute	NULL	Completed	3 Years	75 Years	All	94	Phase 2	United States
6	NCT01384513 (ClinicalTrials.gov)	August 4, 2011	27/6/2011	A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Mali ...	A Two Step Approach to Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantationfor Patie ...	Adult Acute Lymphoblastic Leukemia in Remission;Adult Acute Myeloid Leukemia in Remission;Adult Acut ...	Drug: Fludarabine;Drug: Busulfan;Radiation: Total Body Irradiation (TBI);Biological: Donor Lymphocyt ...	Sidney Kimmel Cancer Center at Thomas Jefferson University	NULL	Active, not recruiting	18 Years	N/A	All	40	Phase 2	United States
7	JPRN-UMIN000006071	2011/08/01	31/08/2011	Allogeneic hematopoietic stem cell transplantationfor aplastic anemia using low-dose anti-thymocyte ...		SAA	Conditioning regimen Fludarabine 30mg/m2/day iv day-6,-5,-4,-3 Cyclophosphamide 25mg/kg/day iv day-6,-5 ...	Kanto Study Group for Cell Therapy	NULL	Complete: follow-up complete	16years-old	65years-old	Male and Female	28	Phase 2	Japan
8	NCT01174108 (ClinicalTrials.gov)	December 10, 2010	31/7/2010	Allogeneic Hematopoietic Stem Cell Transplantationfor Severe Aplastic Anemia and Other Bone Marrow F ...	Allogeneic Hematopoietic Stem Cell Transplantationfor Severe Aplastic Anemia and Other Bone Marrow F ...	Severe Aplastic Anemia;MDS (Myelodysplastic Syndrome)	Device: Miltenyi CD34 Reagent System;Other: Donor derived G-CSF mobilized PBC	National Heart, Lung, and Blood Institute (NHLBI)	NULL	Recruiting	4 Years	80 Years	All	120	Phase 2	United States
9	JPRN-UMIN000004264	2010/11/01	01/11/2010	A Pharmacokinetics (PK)/Phase I study of intravenous (i.v.) administration of mycophenolate mofetil ...		Refractory hematologic disorders, including1. Acute myelogenous leukemia2. Acute lymphoblastic leuke ...	For GVHD prophylaxis, MMFis administered 4-6 h after allo-SCT at a dose of 1000 mg i.v. (diluted to ...	Kobe University Graduate School of Medicine	School of Pharmacy and Pharmaceutical Science, Mukogawa Women's University	Complete: follow-up complete	15years-old	69years-old	Male and Female	10	Phase 1	Japan
10	NCT01319851 (ClinicalTrials.gov)	September 2010	15/9/2010	Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation	Alefacept and Allogeneic Hematopoietic Stem Cell Transplantationfor Children With Non-Malignant Dise ...	Thalassemia;Sickle Cell Disease;Glanzmann Thrombasthenia;Wiskott-Aldrich Syndrome;Chronic-granulomat ...	Drug: Alefacept	Emory University	Children's Healthcare of Atlanta	Terminated	N/A	21 Years	All	3	N/A	United States

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