60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details

臨床試験数 : 235 / 薬物数 : 381 - (DrugBank : 83) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 160

13 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCTs071190032	26/11/2019	21/10/2019	W-JHS AA02	Investigation on the effectiveness of rabbit ATG + cyclosporine + eltrombopag therapy for patients w ...	aplastic anemia	1. The administration of rATG; 2.5 mg/kg, iv. daily, day 1 - day 5 + CsA; 5 mg/kg, po. bid (before b ...	Ishiyama Ken	NULL	Recruiting	>= 18age old	< 80age old	Both	60	Phase 2	Japan
2	NCT03579875 (ClinicalTrials.gov)	November 13, 2018	25/5/2018	T Cell Receptor a/ß TCD HCT in Patients With Fanconi Anemia	T Cell Receptor Alpha/Beta T Cell Depleted (a/ß TCD) Hematopoietic Cell Transplantation in Patients ...	Fanconi Anemia;Severe Aplastic Anemia;Myelodysplastic Syndromes	Drug: Total Body Irradiation (TBI) (Plan 1);Drug: Cyclophosphamide (CY) (Plan 1);Drug: Fludarabine (FL ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	65 Years	All	48	Phase 2	United States
3	NCT02462252 (ClinicalTrials.gov)	October 2015	25/5/2015	Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclospori ...	A Phase IIA, Open-label Study Designed to Evaluate Efficacy and Safety of BL-8040 Followed by Anti-T ...	Aplastic Anemia;Hypoplastic Myelodysplastic Syndrome	Drug: BL-8040;Drug: horse anti-thymocyte globulin (hATG);Drug: Methylprednisolone;Drug: Cyclosporine	BioLineRx, Ltd.	NULL	Recruiting	18 Years	N/A	All	25	Phase 2	United States
4	NCT01624805 (ClinicalTrials.gov)	June 25, 2012	19/6/2012	Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or ...	Phase II Study of Horse Anti-Thymocyte Globulin (hATG), Cyclosporine, Methylprednisolone, and GCSF ( ...	Aplastic Anemia;de Novo Myelodysplastic Syndrome;Myelodysplastic Syndrome;Previously Treated Myelody ...	Biological: Anti-Thymocyte Globulin;Drug: Cyclosporine;Biological: Filgrastim;Drug: Methylprednisolo ...	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	Recruiting	N/A	N/A	All	100	Phase 2	United States
5	NCT00455312 (ClinicalTrials.gov)	August 2007	30/3/2007	Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA	Hematopoietic Stem Cell Transplant For Patients With Dyskeratosis Congenita and Severe Aplastic Anem ...	Dyskeratosis Congenita;Aplastic Anemia	Drug: Campath 1H;Drug: Cyclophosphamide;Drug: Fludarabine;Procedure: Total Body Irradiation;Procedure ...	Masonic Cancer Center, University of Minnesota	NULL	Completed	N/A	70 Years	All	36	Phase 2/Phase 3	United States
6	NCT00806598 (ClinicalTrials.gov)	May 2005	9/12/2008	Thymoglobulin and Cyclosporine in Patients With Aplastic Anemia or Myelodysplastic Syndrome	Phase II Study of Combination of Thymoglobulin, Cyclosporine, Methylprednisone, and Granulocyte Colo ...	Myelodysplastic Syndrome;Aplastic Anemia	Drug: Thymoglobulin;Drug: Cyclosporine;Drug: Methylprednisolone;Drug: G-CSF	M.D. Anderson Cancer Center	Genzyme, a Sanofi Company	Completed	15 Years	N/A	All	53	Phase 2	United States
7	NCT00054236 (ClinicalTrials.gov)	May 2002	5/2/2003	Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With ...	Pilot Study Of Multiple Umbilical Cord Blood Unit Transplantation Following Non-Myeloablative Condit ...	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Multiple Myeloma and Plasma Cell Neoplasm;Mye ...	Biological: anti-thymocyte globulin;Biological: filgrastim;Drug: cyclophosphamide;Drug: fludarabine p ...	Case Comprehensive Cancer Center	NULL	Completed	N/A	120 Years	All	55	Phase 1	United States
8	NCT00053989 (ClinicalTrials.gov)	January 29, 2002	5/2/2003	NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/Disorders	Non-Myeloablative Allogeneic Hematopoietic Peripheral Blood Stem Cell Transplantation for Hematologi ...	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Multiple Myeloma and Plasma Cell Neoplasm;Mye ...	Biological: anti-thymocyte globulin;Biological: graft-versus-tumor induction therapy;Biological: sar ...	Roswell Park Cancer Institute	NULL	Completed	4 Years	75 Years	All	41	Phase 2	United States
9	NCT00017654 (ClinicalTrials.gov)	April 2001	6/6/2001	Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantatio ...		Graft Versus Host Disease;Aplastic Anemia	Drug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: cyclosporine;Drug: methylprednisolone;Pro ...	Northwestern Memorial Hospital	NULL	Active, not recruiting	15 Years	55 Years	Both	3	N/A	United States
10	NCT00003336 (ClinicalTrials.gov)	January 1998	1/11/1999	Pilot Study Of Unrelated UCB Transplant for Non-Malignant Hematologic Conditions	A Pilot Study of Unrelated Umbilical Cord Blood Transplantation in Patients With Severe Aplastic Ane ...	Leukemia;Myelodysplastic Syndromes;Myelodysplastic/Myeloproliferative Diseases	Biological: anti-thymocyte globulin;Drug: busulfan;Drug: cyclophosphamide;Drug: melphalan;Drug: meth ...	Case Comprehensive Cancer Center	National Cancer Institute (NCI)	Completed	N/A	55 Years	Both	6	Phase 2	United States

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