62. 発作性夜間ヘモグロビン尿症 Paroxysmal nocturnal hemoglobinuria Clinical trials / Disease details

臨床試験数 : 271 / 薬物数 : 163 - (DrugBank : 49) / 標的遺伝子数 : 22 - 標的パスウェイ数 : 106

42 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-003440-74-GB (EUCTR)	14/05/2020	17/03/2020	Phase 4, Single-Arm Study of Ravulizumab in Adult Participants with Paroxysmal Nocturnal Hemoglobinu ...	Phase 4, Single-Arm Study of Ravulizumab in Adult Participants with Paroxysmal Nocturnal Hemoglobinu ...	Paroxysmal nocturnal hemoglobinuria (PNH) MedDRA version: 21.1;Level: LLT;Classification code 100556 ...	Trade Name: ULTOMIRIS Product Name: ULTOMIRIS Product Code: ALXN1210 INN or Proposed INN: RAVULIZUMAB	Alexion Pharmaceuticals Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20	Phase 4	United Kingdom
2	EUCTR2017-002370-39-DE (EUCTR)	02/07/2019	15/11/2018	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label, Pharmacokinetic, Noninferiority Stud ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	105	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Finland;Spain;Turkey;Austria;Russian Federation;Italy;United Kingdom;France;Czech Repu ...
3	EUCTR2017-002370-39-NL (EUCTR)	01/07/2019	27/11/2018	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label,Pharmacokinetic, Noninferiority Study ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	105	Phase 3	United States;Czechia;Finland;Spain;Turkey;Austria;Russian Federation;United Kingdom;Italy;France;Cz ...
4	EUCTR2017-002370-39-CZ (EUCTR)	09/04/2019	02/01/2019	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label, Pharmacokinetic, Noninferiority Stud ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 20.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	105	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Finland;Spain;Turkey;Austria;Russian Federation;Italy;United Kingdom;France;Czech Repu ...
5	EUCTR2017-002370-39-AT (EUCTR)	01/04/2019	24/01/2019	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label,Pharmacokinetic, Noninferiority Study ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	105	Phase 3	United States;Finland;Spain;Turkey;Austria;Russian Federation;United Kingdom;Italy;France;Czech Repu ...
6	EUCTR2017-002370-39-SE (EUCTR)	27/03/2019	30/11/2018	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label,Pharmacokinetic, Noninferiority Study ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	105	Phase 3	United States;Czechia;Finland;Spain;Turkey;Austria;Russian Federation;United Kingdom;Italy;France;Cz ...
7	EUCTR2017-002370-39-BE (EUCTR)	13/03/2019	23/11/2018	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label,Pharmacokinetic, Noninferiority Study ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	105	Phase 3	United States;Czechia;Finland;Spain;Turkey;Austria;Russian Federation;United Kingdom;Italy;France;Cz ...
8	EUCTR2017-002370-39-GB (EUCTR)	19/02/2019	26/11/2018	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label, Pharmacokinetic, Noninferiority Stud ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	105	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Finland;Spain;Turkey;Austria;Russian Federation;Italy;United Kingdom;France;Czech Repu ...
9	EUCTR2017-002370-39-ES (EUCTR)	08/02/2019	18/01/2019	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label, Pharmacokinetic, Noninferiority Stud ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 20.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	105	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Finland;Spain;Turkey;Austria;Russian Federation;Italy;United Kingdom;France;Czech Repu ...
10	EUCTR2017-002370-39-FI (EUCTR)	29/01/2019	21/12/2018	This study compares the pharmacokinetics (PK) of ravulizumab subcutaneous (SC) administered via an o ...	A Phase 3, Randomized, Parallel-Group, Multicenter, Open-Label,Pharmacokinetic, Noninferiority Study ...	Paroxysmal Nocturnal Hemoglobinuria MedDRA version: 21.1;Level: LLT;Classification code 10055629;Ter ...	Product Name: Ravulizumab Product Code: ALXN1210 INN or Proposed INN: Fc- and CDR-modified humanised m ...	Alexion Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	105	Phase 3	United States;Czechia;Finland;Spain;Turkey;Austria;Russian Federation;United Kingdom;Italy;France;Cz ...

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