65. 原発性免疫不全症候群 Primary immunodeficiency Clinical trials / Disease details

臨床試験数 : 482 / 薬物数 : 653 - (DrugBank : 119) / 標的遺伝子数 : 92 - 標的パスウェイ数 : 212

18 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04339777 (ClinicalTrials.gov)	September 22, 2020	8/4/2020	Allogeneic Hematopoietic Stem Cell Transplant for People With Primary Immunodeficiency Diseases	A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immunode ...	Lymphoproliferative Disorders;Autoimmune Lymphoproliferative;Immune System Diseases;Common Variable ...	Drug: Busulfan test dose;Drug: Fludarabine;Drug: Busulfan;Drug: Alemtuzumab;Radiation: Total body Irr ...	National Cancer Institute (NCI)	NULL	Suspended	4 Years	69 Years	All	10	Phase 2	United States
2	NCT03910452 (ClinicalTrials.gov)	October 28, 2019	9/4/2019	Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Bus ...	Haploidentical Transplant for Patients With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, B ...	Chronic Granulomatous Disease	Drug: Busulfan;Drug: Alemtuzumab;Drug: Cyclophosphamide;Drug: Sirolimus;Radiation: Total Body Irradi ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Suspended	4 Years	65 Years	All	4	Early Phase 1	United States
3	NCT03333486 (ClinicalTrials.gov)	December 7, 2017	2/11/2017	Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in T ...	A Phase II Trial of Haploidentical Allogeneic Stem Cell Transplantation Utilizing Mobilized Peripher ...	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;Acute Leukemia in Remission;Acute ...	Drug: Cyclophosphamide;Drug: Fludarabine Phosphate;Other: Laboratory Biomarker Analysis;Procedure: Pe ...	Roswell Park Cancer Institute	NULL	Recruiting	1 Year	75 Years	All	58	Phase 2	United States
4	NCT02629120 (ClinicalTrials.gov)	December 17, 2015	10/12/2015	High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamidefor Patien ...	High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamidefor Patien ...	Chronic Granulomatous Disease Transplant	Drug: Alentuzumab (Campath);Drug: Busulfan IV;Drug: Sirolimus;Drug: Cyclophosphamide;Radiation: Total ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Recruiting	4 Years	65 Years	All	50	Phase 1/Phase 2	United States
5	JPRN-UMIN000019532	2015/12/01	01/12/2015	Clinical Phase II Study of hematopoietic stem ctell transplantation for ataxia telangiectasia and re ...	Clinical Phase II Study of hematopoietic stem ctell transplantation for ataxia telangiectasia and re ...	ataxia telangiectasiaDNA damage response disorder	fludarabine 30 mg/m2x5, cyclophosphamide 5mg/kgx4, ATG 1.25mg/kgx4	Graduate Schoool,Dept. of Community Pediatrics,Perinatal and Maternal Medicine,Tokyo Medical and Den ...	NULL	Recruiting	Not applicable	Not applicable	Male and Female	5	Phase 2	Japan
6	NCT03198195 (ClinicalTrials.gov)	March 10, 2015	22/6/2017	Post-transplant Cyclophosphamide in Wiskott-Aldrich Syndrome	Post-transplant Cyclophosphamide for HLA-haploidentical Transplantation in Wiskott-Aldrich Syndrome	Wiskott-Aldrich Syndrome	Procedure: cyclophosphamide	Capital Research Institute of Pediatrics	NULL	Enrolling by invitation	5 Months	10 Years	All	5	N/A	NULL
7	NCT02162420 (ClinicalTrials.gov)	January 2015	10/6/2014	Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia	Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia	Dyskeratosis Congenita;Aplastic Anemia	Drug: Alemtuzumab;Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total Body Irradiation;Biologi ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	70 Years	All	50	N/A	United States
8	NCT02282904 (ClinicalTrials.gov)	October 23, 2014	4/11/2014	Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclop ...	Haploidentical Transplant for Patients With Chronic Granulomatous Disease (CGD) Using Post-Transplan ...	Chronic Granulomatous Disease	Drug: Sirolimus;Biological: Donor peripheral blood stem cells.;Drug: Cyclophosphamide post transplant ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Terminated	2 Years	65 Years	All	7	Phase 1/Phase 2	United States
9	NCT01652092 (ClinicalTrials.gov)	September 4, 2012	25/7/2012	Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies	Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies	SCID;Omenn's Syndrome;Reticular Dysgenesis;Wiskott-Aldrich Syndrome;Bare Lymphocyte Syndrome;Common ...	Drug: Alemtuzumab 0.3 mg;Drug: Cyclophosphamide;Drug: Busulfan;Biological: Stem Cell Transplantation; ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	50 Years	All	30	N/A	United States
10	NCT00455312 (ClinicalTrials.gov)	August 2007	30/3/2007	Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA	Hematopoietic Stem Cell Transplant For Patients With Dyskeratosis Congenita and Severe Aplastic Anem ...	Dyskeratosis Congenita;Aplastic Anemia	Drug: Campath 1H;Drug: Cyclophosphamide;Drug: Fludarabine;Procedure: Total Body Irradiation;Procedure ...	Masonic Cancer Center, University of Minnesota	NULL	Completed	N/A	70 Years	All	36	Phase 2/Phase 3	United States

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