79. 家族性高コレステロール血症（ホモ接合体） Homozygous familial hypercholesterolemia Clinical trials / Disease details

臨床試験数 : 142 / 薬物数 : 114 - (DrugBank : 29) / 標的遺伝子数 : 9 - 標的パスウェイ数 : 18

3 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03510715 (ClinicalTrials.gov)	August 31, 2018	18/4/2018	An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hype ...	An Open-Label Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents Wi ...	Hypercholesterolemia	Drug: Alirocumab SAR236553 (REGN727);Drug: Rosuvastatin;Drug: Ezetimibe;Drug: Cholestyramine;Drug: Ni ...	Sanofi	Regeneron Pharmaceuticals	Completed	8 Years	17 Years	All	18	Phase 3	Brazil;Canada;Denmark;Mexico;Netherlands;Russian Federation;Slovenia;Spain;Taiwan;Turkey;Austria;Fra ...
2	NCT03885921 (ClinicalTrials.gov)	October 25, 2000	20/3/2019	Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatinor Simvastatin in H ...	Long-Term, Open-Label, Safety and Tolerability Study of SCH 58235 in Addition to Atorvastatinor Simv ...	Hypercholesterolemia	Drug: Ezetimibe;Drug: Atorvastatin;Drug: Simvastatin	Organon and Co	NULL	Completed	12 Years	N/A	All	44	Phase 3	NULL
3	NCT03884452 (ClinicalTrials.gov)	May 3, 2000	6/3/2019	Ezetimibe (SCH 58235) Taken With Either Atorvastatinor Simvastatin in Participants With Familial Hyp ...	A Phase III Efficacy And Safety Study of Ezetimibe (SCH58235) 10 mg in Addition to Atorvastatinor Si ...	Familial Hypercholesterolemia	Drug: Atorvastatin;Drug: Simvastatin;Drug: Ezetimibe;Drug: Placebo for Ezetimibe	Organon and Co	NULL	Completed	12 Years	N/A	All	50	Phase 3	NULL

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