86. 肺動脈性肺高血圧症 Pulmonary arterial hypertension Clinical trials / Disease details
臨床試験数 : 1,181 / 薬物数 : 701 - (DrugBank : 126) / 標的遺伝子数 : 105 - 標的パスウェイ数 : 192
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02507011 (ClinicalTrials.gov) | January 31, 2016 | 22/7/2015 | Beta-blockers in Pulmonary Arterial Hypertension | Beta-blockers in Pulmonary Arterial Hypertension - A Phase 2 Double-Blind, Placebo-Controlled, Crossover Study Evaluating the Efficacy, and Safety of Carvedilol for Right Ventricular Dysfunction in Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension | Drug: Carvedilol;Drug: Placebo | University of Minnesota | NULL | Terminated | 18 Years | N/A | All | 2 | Phase 2 | United States |
| 2 | NCT02120339 (ClinicalTrials.gov) | May 2014 | 17/4/2014 | Carvedilol PAH A Pilot Study of Efficacy and Safety | Beta Blockers in Pulmonary Arterial Hypertension (PAH) A Pilot Study of Efficacy and Safety | Pulmonary Hypertension;Cardiac MRI <40 | Drug: Carvedilol | University of Minnesota | NULL | Terminated | 18 Years | 99 Years | All | 5 | Phase 1 | United States |
| 3 | NCT01586156 (ClinicalTrials.gov) | December 2012 | 23/4/2012 | PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol) | Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure | Pulmonary Hypertension | Drug: Carvedilol;Drug: placebo | The Cleveland Clinic | National Institutes of Health (NIH);National Heart, Lung, and Blood Institute (NHLBI) | Completed | 18 Years | 65 Years | All | 30 | N/A | United States |
| 4 | NCT01723371 (ClinicalTrials.gov) | September 2012 | 31/10/2012 | Beta Blockers for Treatment of Pulmonary Arterial Hypertension in Children | Beta Blockers for Treatment of Pulmonary Arterial Hypertension in Children | Pulmonary Arterial Hypertension | Drug: Carvedilol | The Hospital for Sick Children | NULL | Withdrawn | 8 Years | 17 Years | Both | 0 | Phase 1/Phase 2 | Canada |
| 5 | NCT00964678 (ClinicalTrials.gov) | June 2010 | 24/8/2009 | Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension | Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension | Drug: Carvedilol | Virginia Commonwealth University | GlaxoSmithKline | Completed | 18 Years | N/A | All | 10 | Phase 1/Phase 2 | United States |
| 6 | NCT00240656 (ClinicalTrials.gov) | October 2005 | 17/10/2005 | Spironolactone Combined With Captopril and Carvedilol for the Treatment of Pulmonary Arterial Hypertension | Official Title: Spironolactone Combined With Captopril and Carvedilol for the Treatment of Patients With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease—Focus on Pulmonary Artery Remodeling | Hypertension, Pulmonary | Drug: spironolactone captopril carvedilol | Hebei Medical University | NULL | Completed | N/A | 80 Years | Both | Phase 1 | China |