86. 肺動脈性肺高血圧症 Pulmonary arterial hypertension Clinical trials / Disease details

臨床試験数 : 1,181 / 薬物数 : 701 - (DrugBank : 126) / 標的遺伝子数 : 105 - 標的パスウェイ数 : 192

134 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04039464 (ClinicalTrials.gov)	April 1, 2022	1/7/2019	Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension	Kids MoD PAH Trial: Mono- vs. Duo-Therapy for Pediatric Pulmonary Arterial Hypertension	Pediatric Pulmonary Hypertension	Drug: Mono-Therapy with Sildenafil;Drug: Duo-Therapy with Sildenafil + Bosentan	Johns Hopkins University	NULL	Not yet recruiting	4 Months	18 Years	All	100	Phase 3	United States
2	EUCTR2013-004362-34-LV (EUCTR)	03/10/2018	02/07/2018	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	Pulmonary Arterial Hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Product Name: Sildenafil Product Code: UK 092480 INN or Proposed INN: Sildenafil Other descriptive name ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	429	Phase 3;Phase 4	United States;Portugal;Serbia;Hong Kong;Greece;Spain;Thailand;Ukraine;Israel;Russian Federation;Mala ...
3	NCT04994860 (ClinicalTrials.gov)	March 22, 2018	29/7/2021	Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil	An Open-Label, Three Period, Fixed Sequence Study to Assess the Effect of a Single Dose of BIA 5-105 ...	Pulmonary Arterial Hypertension	Drug: BIA 5-1058;Drug: Sildenafil	Bial - Portela C S.A.	NULL	Completed	18 Years	45 Years	All	20	Phase 1	Germany
4	NCT03364244 (ClinicalTrials.gov)	November 30, 2017	30/11/2017	Revatio Special Investigation for Long-term Use in Pediatric Patients	REVATIO SPECIAL INVESTIGATION - INVESTIGATION FOR LONG-TERM USE OF REVATIO IN PEDIATRIC PATIENTS -	Pulmonary Arterial Hypertension	Drug: Sildenafil	Pfizer	NULL	Recruiting	N/A	14 Years	All	190		Japan
5	NCT03431649 (ClinicalTrials.gov)	April 1, 2017	29/7/2017	Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Children	Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Pulmonary Arterial Hypertension Chi ...	Pediatric Pulmonary Hypertension	Drug: Beraprost Sodium;Drug: Sildenafil Citrate	Dr. Soetomo General Hospital	NULL	Completed	1 Year	17 Years	All	40	Phase 4	Indonesia
6	NCT02891850 (ClinicalTrials.gov)	January 11, 2017	26/8/2016	Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy	A Prospective, Randomized, International, Multicenter, Double-arm, Controlled, Open-label Study of R ...	Pulmonary Arterial Hypertension	Drug: Adempas (Riociguat, BAY63-2521);Drug: Sildenafil;Drug: Tadalafil	Bayer	NULL	Completed	18 Years	75 Years	All	225	Phase 4	United States;Austria;Belgium;Brazil;Canada;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, ...
7	NCT03053739 (ClinicalTrials.gov)	December 2016	29/12/2016	To Compare the Efficacy of Combination Therapy vs Monotherapy for Pulmonary Arterial Hypertension in ...	Randomized Controlled Trial to Compare the Efficacy of Combination Therapy vs Monotherapy for Pulmon ...	Associated Pulmonary Arterial Hypertension	Drug: Sildenafil 20mg and Bosentan 62.5mg;Drug: Sildenafil 20mg and Placebo	Postgraduate Institute of Medical Education and Research	NULL	Recruiting	18 Years	N/A	All	50	Phase 4	India
8	EUCTR2013-004362-34-HR (EUCTR)	21/10/2015	26/05/2015	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	Pulmonary Arterial Hypertension MedDRA version: 18.1;Level: PT;Classification code 10064911;Term: Pu ...	Product Name: Sildenafil Product Code: UK 092480 INN or Proposed INN: Sildenafil Other descriptive name ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	429		United States;Portugal;Serbia;Taiwan;Hong Kong;Greece;Thailand;Spain;Ukraine;Israel;Russian Federati ...
9	EUCTR2013-004362-34-SE (EUCTR)	26/08/2015	13/03/2014	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	Pulmonary Arterial Hypertension MedDRA version: 20.0;Level: PT;Classification code 10064911;Term: Pu ...	Product Name: Sildenafil Product Code: UK 092480 INN or Proposed INN: Sildenafil Other descriptive name ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	429	Phase 3;Phase 4	United States;Portugal;Serbia;Taiwan;Hong Kong;Greece;Thailand;Spain;Ukraine;Israel;Russian Federati ...
10	EUCTR2013-004362-34-PT (EUCTR)	08/05/2015	18/02/2015	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	A MULTINATIONAL, MULTICENTER STUDY TO ASSESS THE EFFECTS OF ORAL SILDENAFILON MORTALITY IN ADULTS WI ...	Pulmonary Arterial Hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Product Name: Sildenafil Product Code: UK 092480 INN or Proposed INN: Sildenafil Other descriptive name ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	429	Phase 3;Phase 4	Serbia;Portugal;United States;Taiwan;Hong Kong;Greece;Spain;Thailand;Ukraine;Russian Federation;Isra ...

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