89. リンパ脈管筋腫症 Lymphangioleiomyomatosis Clinical trials / Disease details

臨床試験数 : 39 / 薬物数 : 46 - (DrugBank : 20) / 標的遺伝子数 : 27 - 標的パスウェイ数 : 137

12 trials found

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Showing 1 to 10 of 12 diseases

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02432560 (ClinicalTrials.gov)	March 2015	4/3/2015	Safety and Durability of Sirolimus for Treatment of LAM	Multicenter International Durability and Safety of Sirolimus in LAM Trial (MIDAS)	Lymphangioleiomyomatosis	Drug: Sirolimus;Drug: Everolimus	University of Cincinnati	Rare Diseases Clinical Research Network;National Institutes of Health (NIH);National Heart, Lung, an ...	Recruiting	18 Years	N/A	Female	600		United States
2	NCT02061397 (ClinicalTrials.gov)	March 2014	23/1/2014	Safety of Simvastatin in LAM and TSC	The Safety of Simvastatin (SOS) in Patients With Pulmonary Lymphangioleiomyomatosis (LAM) and With T ...	Lymphangioleiomyomatosis;Tuberous Sclerosis Complex	Drug: Simvastatin;Drug: Sirolimus Oral Product;Drug: Everolimus Oral Product	University of Pennsylvania	The LAM Foundation	Completed	18 Years	N/A	Female	10	Phase 1/Phase 2	United States
3	EUCTR2010-019825-32-IT (EUCTR)	28/07/2010	18/05/2010	An exploratory, open label, non-randomized, within-patient multiple dose-escalation safety, tolerabi ...	An exploratory, open label, non-randomized, within-patient multiple dose-escalation safety, tolerabi ...	Lymphangioleiomyomatosis MedDRA version: 12.1;Level: LLT;Classification code 10049459;Term: Lymphang ...	INN or Proposed INN: Everolimus INN or Proposed INN: Everolimus INN or Proposed INN: Everolimus	NOVARTIS FARMA	NULL	Not Recruiting			Female: yes Male: no	24		France;Italy
4	EUCTR2010-019825-32-FR (EUCTR)	29/06/2010	28/05/2010	An exploratory, open label, non-randomized, within-patient multiple dose-escalation safety, tolerabi ...	An exploratory, open label, non-randomized, within-patient multiple dose-escalation safety, tolerabi ...	Lymphangioleiomyomatosis MedDRA version: 12.1;Level: LLT;Classification code 10049459;Term: Lymphang ...	Product Code: RAD001 INN or Proposed INN: everolimus Trade Name: Afinitor Product Code: RAD001 INN or Pr ...	Novartis Pharma Service AG	NULL	Not Recruiting			Female: yes Male: no	24		France;Italy
5	EUCTR2008-002113-48-NL (EUCTR)	16/03/2010	02/04/2009	A randomized double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	A randomized double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	Angiomyolipoma in patients with either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomy ...	Product Name: RAD001 Product Code: RAD001 INN or Proposed INN: EVEROLIMUS	Novartis Pharma Services AG	NULL	Not Recruiting			Female: yes Male: yes	99		France;Spain;Germany;Netherlands;Italy;United Kingdom
6	NCT01059318 (ClinicalTrials.gov)	January 2010	28/1/2010	A Study to Determine the Safety and Effectiveness of RAD001 (Everolimus) in Patients With Lymphangio ...	An Exploratory, Open-label, Non-randomized, Within-patient Multiple Dose-escalation Safety, Tolerabi ...	Lymphangioleiomyomatosis	Drug: Everolimus	Novartis Pharmaceuticals	NULL	Completed	18 Years	N/A	Female	24	Phase 2	United States;France;Italy;Germany
7	EUCTR2008-002113-48-IT (EUCTR)	03/09/2009	07/09/2009	A randomized, double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	A randomized, double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	Angiomyolipoma in patients with either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomy ...	Product Name: RAD001 Product Code: RAD001 INN or Proposed INN: Everolimus	NOVARTIS FARMA	NULL	Not Recruiting			Female: yes Male: yes	99		France;Spain;Netherlands;Germany;United Kingdom;Italy
8	EUCTR2008-002113-48-GB (EUCTR)	06/08/2009	22/05/2009	Efficacy and Safety of RAD001 in patients aged 18 and over with Angiomyolipoma associated with eithe ...	A randomized double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	Angiomyolipoma in patients with either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomy ...	Trade Name: Afinitor 5mg Tablets Product Name: RAD001 Product Code: RAD001 INN or Proposed INN: Everolim ...	Novartis Pharma Services AG	NULL	Not Recruiting			Female: yes Male: yes	118	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	France;United States;Canada;Spain;Russian Federation;Netherlands;Germany;Italy;Japan;United Kingdom
9	NCT00790400 (ClinicalTrials.gov)	April 2009	10/11/2008	Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Eithe ...	A Randomized, Double-blind, Placebo-controlled Study of RAD0001 in the Treatment of Angiomyolipoma i ...	Tuberous Sclerosis Complex (TSC);Lymphangioleiomyomatosis (LAM)	Drug: Everolimus (RAD001);Drug: Everolimus Placebo	Novartis Pharmaceuticals	NULL	Completed	18 Years	N/A	All	118	Phase 3	United States;Canada;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United K ...
10	EUCTR2008-002113-48-FR (EUCTR)	18/03/2009	19/03/2009	A randomized double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	A randomized double-blind, placebo-controlled study of RAD001 in the treatment of Angiomyolipoma in ...	Angiomyolipoma in patients with either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomy ...	Product Name: RAD001 Product Code: RAD001 INN or Proposed INN: EVEROLIMUS	Novartis Pharma Services AG	NULL	Not Recruiting			Female: yes Male: yes	99	Phase 3	France;Spain;Netherlands;Germany;Italy;United Kingdom

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