93. 原発性胆汁性胆管炎 Primary biliary cholangitis Clinical trials / Disease details


臨床試験数 : 282 薬物数 : 245 - (DrugBank : 56) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 113

  
3 trials found
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1NCT02376335
(ClinicalTrials.gov)
October 201224/2/2015B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary CirrhosisB-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary CirrhosisFatigue;Primary Biliary CirrhosisBiological: Rituximab;Other: PlaceboNewcastle-upon-Tyne Hospitals NHS TrustNational Institute for Health Research, United Kingdom;Department of Health, United Kingdom;Newcastle UniversityCompleted18 YearsN/AAll71Phase 2United Kingdom
2EUCTR2012-000145-12-GB
(EUCTR)
15/08/201204/07/2012Pilot study of Rituximab for the treatment of fatigue in PBCRituximab for the Treatment of Fatigue in Primary Biliary Cirrhosis (PBC) - RITPBC Study Severe fatigue in Primary Biliary Cirrhosis
MedDRA version: 18.0;Level: PT;Classification code 10004661;Term: Biliary cirrhosis primary;System Organ Class: 10019805 - Hepatobiliary disorders ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: MabThera®
Product Name: MabThera®
INN or Proposed INN: Rituximab
Other descriptive name: N/A
The Newcastle upon Tyne Hospitals NHS Foundation TrustNULLNot Recruiting Female: yes
Male: yes
58 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): noUnited Kingdom
3NCT00364819
(ClinicalTrials.gov)
January 200715/8/2006Initial Study of Rituximab to Treat Primary Biliary CirrhosisEffects of Rituximab (Rituxan) on B Cell and AMA Response in Patients With Primary Biliary CirrhosisPrimary Biliary CirrhosisDrug: rituximabUniversity of California, DavisGenentech, Inc.Completed18 Years65 YearsFemale6Phase 1/Phase 2United States