DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
93. 原発性胆汁性胆管炎
Primary biliary cholangitis
Clinical trials
/
Disease details
臨床試験数
:
282
/
薬物数
:
245
- (
DrugBank
:
56
) /
標的遺伝子数
:
35
-
標的パスウェイ数
:
113
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3 trials found
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No.
TrialID
Date_
enrollment
Date_
registration
Public_title
Scientific_title
Condition
Intervention
Primary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
Phase
Countries
1
NCT02376335
(
ClinicalTrials.gov
)
October 2012
24/2/2015
B-Cell Depleting Therapy (
Rituximab
) as a Treatment for Fatigue in Primary Biliary Cirrhosis
B-Cell Depleting Therapy (
Rituximab
) as a Treatment for Fatigue in Primary Biliary Cirrhosis
Fatigue;Primary Biliary Cirrhosis
Biological:
Rituximab
;Other: Placebo
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom;Department of Health, United Kingdom;Newcastle University
National Institute for Health Research, United Kingdom;Department of Health, United Kingdom;Newcastl ...
Completed
18 Years
N/A
All
71
Phase 2
United Kingdom
2
EUCTR2012-000145-12-GB
(
EUCTR
)
15/08/2012
04/07/2012
Pilot study of
Rituximab
for the treatment of fatigue in PBC
Rituximab
for the Treatment of Fatigue in Primary Biliary Cirrhosis (PBC) - RITPBC Study
Severe fatigue in Primary Biliary Cirrhosis
MedDRA version: 18.0;Level: PT;Classification code 10004661;Term: Biliary cirrhosis primary;System Organ Class: 10019805 - Hepatobiliary disorders ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Severe fatigue in Primary Biliary Cirrhosis
MedDRA version: 18.0;Level: PT;Classification code 10004 ...
Trade Name:
MabThera
®
Product Name:
MabThera
®
INN or Proposed INN:
Rituximab
Other descriptive name: N/A
Trade Name:
MabThera
®
Product Name:
MabThera
®
INN or Proposed INN:
Rituximab
Other descriptive name: N/ ...
The Newcastle upon Tyne Hospitals NHS Foundation Trust
NULL
Not Recruiting
Female: yes
Male: yes
58
Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): no
Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...
United Kingdom
3
NCT00364819
(
ClinicalTrials.gov
)
January 2007
15/8/2006
Initial Study of
Rituximab
to Treat Primary Biliary Cirrhosis
Effects of
Rituximab
(Rituxan) on B Cell and AMA Response in Patients With Primary Biliary Cirrhosis
Primary Biliary Cirrhosis
Drug:
rituximab
University of California, Davis
Genentech, Inc.
Completed
18 Years
65 Years
Female
6
Phase 1/Phase 2
United States