96. クローン病 Crohn disease Clinical trials / Disease details


臨床試験数 : 2,400 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215

  
5 trials found
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PhaseCountries
1NCT05028946
(ClinicalTrials.gov)
October 28, 202124/8/2021A Study of Oral Foralumab in Participants With Moderate to Severely Active Crohn's DiseaseA Phase IB Multiple Ascending Dose Study of Safety and Tolerability of Orally Administered Foralumab, a Fully Human Anti-CD3 Monoclonal Antibody, in Subjects With Moderate to Severely Active Crohn's DiseaseCrohn's DiseaseDrug: ForalumabTiziana Life Sciences, PLCNULLNot yet recruiting18 Years70 YearsAll16Phase 1NULL
2NCT00630643
(ClinicalTrials.gov)
January 200628/2/2008NI-0401 in Active Crohn's DiseaseA Phase I/IIa, Double-Blind, Placebo-Controlled, Dose-Escalation Study of NI-0401 in Patients With Moderate to Severe Active Crohn´s DiseaseModerate to Severe Crohn's DiseaseBiological: NI-0401 (anti-CD3 mAB);Drug: PlaceboNovImmune SANULLCompleted18 Years70 YearsBoth40Phase 1/Phase 2NULL
3EUCTR2004-004387-72-AT
(EUCTR)
11/10/200509/06/2005A Phase IIa, Open-label Study of Visilizumab for Treatment of Perianal Fistulas in Patients with Crohn’s Disease. - N/AA Phase IIa, Open-label Study of Visilizumab for Treatment of Perianal Fistulas in Patients with Crohn’s Disease. - N/A Crohn’s disease (CD) in patients with at least one perianal fistula.
MedDRA version: 7.1;Level: LLT;Classification code 10011401
Product Name: Visilizumab
Product Code: HuM291
INN or Proposed INN: Visilizumab
Other descriptive name: Anti-CD3 Monoclonal antibody
Protein Design Labs, Inc.NULLNot RecruitingFemale: yes
Male: yes
18Phase 2Austria;Germany
4EUCTR2004-004387-72-DE
(EUCTR)
03/06/200507/01/2005A Phase IIa, Open-label Study of Visilizumab for Treatment of Perianal Fistulas in Patients with Crohn’s Disease. - N/AA Phase IIa, Open-label Study of Visilizumab for Treatment of Perianal Fistulas in Patients with Crohn’s Disease. - N/A Crohn’s disease (CD) in patients with at least one perianal fistula.
MedDRA version: 7.1;Level: LLT;Classification code 10011401
Product Name: Visilizumab
Product Code: HuM291
INN or Proposed INN: Visilizumab
Other descriptive name: Anti-CD3 Monoclonal antibody
PDL BioPharma, Inc.NULLNot RecruitingFemale: yes
Male: yes
18Phase 2Germany
5EUCTR2004-004388-31-DE
(EUCTR)
03/06/200507/01/2005A Phase IIa, Open-label Study of Visilizumab in Patients with Moderate-to-Severe Inflammatory, Nonstricturing, Nonpenetrating Forms of Crohn’s Disease - N/AA Phase IIa, Open-label Study of Visilizumab in Patients with Moderate-to-Severe Inflammatory, Nonstricturing, Nonpenetrating Forms of Crohn’s Disease - N/A Moderate-to-severe inflammatory, nonstricturing, nonpenetrating Crohn’s disease (CD).
MedDRA version: 7.1;Level: LLT;Classification code 10011401
Product Name: Visilizumab
Product Code: HuM291
INN or Proposed INN: Visilizumab
Other descriptive name: Anti-CD3 Monoclonal antibody
PDL BioPharma, IncNULLNot RecruitingFemale: yes
Male: yes
18Phase 2Germany