96. クローン病 Crohn disease Clinical trials / Disease details
臨床試験数 : 2,400 / 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT01765439 (ClinicalTrials.gov) | February 2014 | 7/1/2013 | The Effect of VSL#3 Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel Disease | The Effect of VSL#3 (Original De Simone Formulation) Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel Disease | Crohn Disease;Ulcerative Colitis | Dietary Supplement: VSL#3 (Original De Simone formulation) | Charles University, Czech Republic | Iscare i.v.f., Czech Republic;CD Investments srl;University Of Perugia;University of Roma La Sapienza | Active, not recruiting | N/A | N/A | All | 79 | N/A | Czechia;Czech Republic |
2 | NCT01632462 (ClinicalTrials.gov) | September 2012 | 25/6/2012 | A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease | A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease | Crohn's Disease | Drug: VSL#3 | Federico II University | NULL | Recruiting | 5 Years | 17 Years | Both | 30 | Phase 4 | Italy |
3 | NCT01548014 (ClinicalTrials.gov) | January 2010 | 17/2/2012 | The Effect of a Probiotic Preparation (VSL#3) Plus Infliximab in Children With Crohn's Disease | Reduction in Frequency of Infliximab Administration From q 8 Weeks to q 12 Weeks in Children With Crohn's Disease Receiving Probiotic VSL#3 Supplementation: A Pilot Study | Crohn's Disease | Dietary Supplement: VSL#3 | Samsung Medical Center | NULL | Recruiting | 13 Years | 17 Years | Both | 1 | Phase 3 | Korea, Republic of |
4 | NCT00367705 (ClinicalTrials.gov) | August 2009 | 22/8/2006 | VSL#3 Treatment in Children With Crohn's Disease | Double-blind Placebo Controlled Trial of VSL#3 in Children With Crohn's Disease | Crohn's Disease | Dietary Supplement: VSL#3®;Dietary Supplement: Placebo | Hadassah Medical Organization | NULL | Not yet recruiting | 6 Years | 18 Years | Both | 300 | Phase 4 | Israel |
5 | NCT00944736 (ClinicalTrials.gov) | July 2009 | 22/7/2009 | Effect of VSL#3 on Intestinal Permeability in Pediatric Crohn's Disease | Effect of Probiotic VSL#3 on Intestinal Permeability of Pediatric Patients With Crohn's Disease in Remission | Crohn's Disease | Dietary Supplement: VSL#3;Dietary Supplement: Placebo | Children's Mercy Hospital Kansas City | VSL Pharmaceuticals | Completed | 11 Years | 17 Years | Both | 12 | Phase 3 | United States |
6 | NCT00114465 (ClinicalTrials.gov) | June 2005 | 14/6/2005 | VSL#3 Versus Placebo in Maintenance of Remission in Crohn's Disease | Randomized, Double-Blind, Placebo-Controlled Study of VSL#3 Versus Placebo in the Maintenance of Remission in Crohn's Disease | Crohn's Disease | Drug: VSL#3;Other: Placebo | Orphan Australia | NULL | Completed | 18 Years | 75 Years | Both | 38 | Phase 4 | Australia |
7 | NCT00175292 (ClinicalTrials.gov) | December 2003 | 13/9/2005 | A Randomized Controlled Trial of VSL#3 for the Prevention of Endoscopic Recurrence Following Surgery for Crohn's Disease. | A Randomized and Placebo-Controlled Double-Blind Multicentre Study to Determine the Efficacy and Safety of VSL#3 Probiotic Food Supplement Mixture in Prevention of Endoscopic Recurrence in Crohn's Disease Patients With Ileocolonic Surgical Resection and Small Intestine to Colon Anastomosis. | Crohn's Disease;Inflammatory Bowel Disease | Drug: Probiotic - VSL#3 | University of Alberta | Canadian Institutes of Health Research (CIHR) | Completed | 16 Years | N/A | Both | 120 | Phase 3 | Canada |