97. 潰瘍性大腸炎 Ulcerative colitis Clinical trials / Disease details

臨床試験数 : 2,527 / 薬物数 : 1,465 - (DrugBank : 259) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

93 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2018-002378-30-HU (EUCTR)	01/03/2022	15/12/2021	OPEN LABEL, MAINTENANCE STUDY OF ORAL TOFACITINIBIN CHILDREN WITH MODERATE TO SEVERE ULCERATIVE COLI ...	OPEN-LABEL INDUCTION AND MAINTENANCE STUDY OF ORAL CP-690,550 (TOFACITINIB) IN CHILDREN WITH MODERAT ...	MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS MedDRA version: 20.1;Level: LLT;Classification code ...	Trade Name: XELJANZ Product Name: Tofacitinib citrate Product Code: CP -690,550-10 INN or Proposed INN: t ...	Pfizer Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	120	Phase 3	United States;Slovakia;Finland;Spain;Israel;United Kingdom;Italy;France;Hungary;Canada;Belgium;Polan ...
2	NCT05186623 (ClinicalTrials.gov)	February 5, 2022	22/12/2021	Prediction Model for Response to Biologics and Small Molecular Agent for UC	Establishment of Prediction Model of Biologics and Small Molecular Agent for Patients With Ulcerativ ...	Ulcerative Colitis	Drug: Vedolizumab , Ustekinumab, or Tofacitinib	Asan Medical Center	NULL	Recruiting	18 Years	79 Years	All	300		Korea, Republic of
3	NCT05112263 (ClinicalTrials.gov)	December 1, 2021	26/10/2021	Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative Colitis	TofacitinibVersus Cyclosporine for Steroid Refractory Acute Severe Ulcerative Colitis: An Open Label ...	Ulcerative Colitis	Drug: Tofacitinib;Drug: Cyclosporine	Postgraduate Institute of Medical Education and Research	All India Institute of Medical Sciences, New Delhi	Not yet recruiting	18 Years	65 Years	All	96	N/A	NULL
4	EUCTR2021-002211-65-ES (EUCTR)	13/08/2021	11/06/2021	EFFECT OF TOFACITINIB ON COAGULATION	EFFECT OF TOFACITINIB ON COAGULATION AND PLATELET FUNCTION, AND ITS ROLE IN THROMBOEMBOLIC EVENTS	ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative col ...	Trade Name: Adalimumab INN or Proposed INN: ADALIMUMAB Trade Name: Infliximab INN or Proposed INN: INFL ...	Fundación Española de Gastroenterología	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	Spain
5	JPRN-jRCT2071210075	12/08/2021	07/10/2021	Evaluation of Oral Tofacitinibin Children Aged 2 to 17 Years Old Suffering From Moderate to Severe U ...	OPEN-LABEL INDUCTION AND MAINTENANCE STUDY OF ORAL CP-690,550 (TOFACITINIB) IN CHILDREN WITH MODERAT ...	Ulcerative Colitis	Drug: tofacitinib Open label tofacitinib5 mg BID weight based adult equivalent with the option for i ...	Kawai Norisuke	NULL	Recruiting	>= 2age old	<= 17age old	Both	120	Phase 3	Australia;Canada;United States;Japan
6	NCT04624230 (ClinicalTrials.gov)	August 12, 2021	26/10/2020	Evaluation of Oral Tofacitinibin Children Aged 2 to 17 Years Old Suffering From Moderate to Severe U ...	OPEN-LABEL INDUCTION AND MAINTENANCE STUDY OF ORAL CP-690,550 (TOFACITINIB) IN CHILDREN WITH MODERAT ...	Ulcerative Colitis	Drug: tofacitinib	Pfizer	NULL	Recruiting	2 Years	17 Years	All	120	Phase 3	United States;Australia;Canada;Israel;Japan;Poland;Spain
7	NCT04925973 (ClinicalTrials.gov)	June 1, 2021	8/6/2021	Tofacitinib for Hospitalized Acute Severe Ulcerative Colitis Management	Tofacitinib for Hospitalized Acute Severe Ulcerative Colitis Management (the TRIUMPH Study)	Ulcerative Colitis Acute	Drug: Tofacitinib 10 MG [Xeljanz]	McMaster University	University of Manitoba;University of British Columbia;McGill University;University of Alberta	Recruiting	18 Years	N/A	All	26	Phase 2	Canada
8	NCT04424303 (ClinicalTrials.gov)	December 7, 2020	8/6/2020	Tofacitinib in Adult Patients With Moderate to Severe Ulcerative Colitis	Evaluation of the Clinical Benefit of ToFAcitinibTreatment in Patients With Moderate to Severe Ulcer ...	Ulcerative Colitis	Drug: Tofacitinib	Pfizer	NULL	Recruiting	18 Years	N/A	All	280		France
9	NCT04505410 (ClinicalTrials.gov)	November 18, 2020	5/8/2020	Xeljanz and Healthy Diet	A Randomized Control Study to Examine the Influence of a Healthy Diet on Moderate to Severe Ulcerati ...	Ulcerative Colitis	Drug: Tofacitinib;Other: Fast Mimicking Diet	University of Miami	Pfizer	Recruiting	18 Years	N/A	All	76	Phase 3	United States
10	EUCTR2020-004391-18-FR (EUCTR)	28/10/2020	14/09/2020	IMPACT OF ANTI-TNF, VEDOLIZUMAB AND TOFACITINIBON AORTIC STIFFNESS, CAROTID INTIMA-MEDIA THICKNESS A ...	IMPACT OF ANTI-TNF, VEDOLIZUMAB AND TOFACITINIBON AORTIC STIFFNESS, CAROTID INTIMA-MEDIA THICKNESS A ...	ulcerative colitis;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: Inflectra 100 mg Product Name: Inflectra 100 mg Trade Name: AMGEVITA Product Name: AMGEVITA Tr ...	CHU Amiens-Picardie	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 4	France

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