299. Cystic fibrosis Clinical trials / Disease details


Clinical trials : 1,696 Drugs : 1,644 - (DrugBank : 272) / Drug target genes : 96 - Drug target pathways : 170

  
4 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Status
Inclusion_
agemin
Inclusion_
agemax
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PhaseCountries
1EUCTR2016-001619-19-NL
(EUCTR)
27/03/201727/03/2017Genistein as an add-on treatment for CF?Genistein as an add-on treatment for CF? - Cystic Fibrosis
;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Product Name: Genistein
INN or Proposed INN: genistein
Other descriptive name: GENISTEIN
UMC UtrechtNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Phase 2Netherlands
2EUCTR2014-000817-30-NL
(EUCTR)
14/08/201422/05/2014Comparing the effect of curcumin and genistein to treatment with Ivacaftor in CF patients with a class III mutationComparing the effect of curcumin and genistein to treatment with Ivacaftor in CF patients with a class III mutation - TICTAC-study Cystic Fibrosis;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]Trade Name: Ivacaftor/Kalydeco
Product Name: Curcuma Longa Extract cpl formaat 00 23,2 x 8,5 mm 723 mg
INN or Proposed INN: curcumin
Other descriptive name: CURCUMIN
Product Name: Genisteine Plus 150 mg cpl formaat 1 18,7 x 6,4 mm 438 mg
INN or Proposed INN: genistein
Other descriptive name: GENISTEIN
University Medical Centre UtrechtNULLNot RecruitingFemale: yes
Male: yes
Phase 2Netherlands
3NCT00590538
(ClinicalTrials.gov)
February 200327/12/2007Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis)A Pilot Trial of Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygous Cystic Fibrosis PatientsCystic FibrosisDrug: Sodium 4-Phenylbutyrate;Drug: Genistein (Unconjugated Isoflavones 100);Drug: PlaceboChildren's Hospital of PhiladelphiaCystic Fibrosis Foundation TherapeuticsTerminated18 YearsN/AAll9Phase 1/Phase 2United States
4NCT00016744
(ClinicalTrials.gov)
September 200131/5/2001Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis)A Pilot Trial of Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous Cystic Fibrosis PatientsCystic FibrosisDrug: Sodium 4-Phenylbutyrate (4PBA);Drug: Unconjugated Isoflavones 100 (PTI G-4660, 87% Genistein);Drug: PlaceboChildren's Hospital of PhiladelphiaCystic Fibrosis Foundation Therapeutics;National Center for Research Resources (NCRR)Completed18 YearsN/ABoth12Phase 1/Phase 2United States