Vorinostat ( DrugBank: Vorinostat )


3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
19ライソゾーム病1
75クッシング病1
96クローン病1

19. ライソゾーム病


臨床試験数 : 854 薬物数 : 716 - (DrugBank : 105) / 標的遺伝子数 : 70 - 標的パスウェイ数 : 191
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02124083
(ClinicalTrials.gov)
April 25, 201425/4/2014Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1Neimann-Pick DiseaseDrug: VorinostatEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Washington University School of Medicine;Weill Medical College of Cornell UniversityCompleted18 Years60 YearsAll12Phase 1/Phase 2United States

75. クッシング病


臨床試験数 : 203 薬物数 : 191 - (DrugBank : 51) / 標的遺伝子数 : 62 - 標的パスウェイ数 : 128
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04339751
(ClinicalTrials.gov)
March 24, 20228/4/2020Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s DiseaseThe Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing's DiseaseCushing's DiseaseDrug: VorinostatNational Institute of Neurological Disorders and Stroke (NINDS)NULLNot yet recruiting18 YearsN/AAll22Phase 2United States

96. クローン病


臨床試験数 : 2,400 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03167437
(ClinicalTrials.gov)
October 30, 201724/5/2017An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With UstekinumabAn Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn's Disease and Maintenance Therapy With UstekinumabCrohn's DiseaseDrug: Vorinostat;Drug: UstekinumabNational Institute of Allergy and Infectious Diseases (NIAID)NULLRecruiting18 Years65 YearsAll35Phase 1/Phase 2United States